Immune complexes-mediated activation of neutrophils in systemic lupus erythematosus is dependent on RNA recognition by toll-like receptor 8., PMID:39776899
Small molecule inhibitors of IL-1R1/IL-1β interaction identified via transfer machine learning QSAR modelling., PMID:39515709
Effects of Aeromonas infection on the immune system, physical barriers and microflora structure in the intestine of juvenile grass carp (Ctenopharyngodon idella)., PMID:39059563
IRAK4 is an immunological checkpoint in neuropsychiatric systemic lupus erythematosus., PMID:39014006
Preparation, characterization and immune response of chitosan‑gold loaded Myricaria germanica polysaccharide., PMID:38070794
IL-33 Suppresses the Progression of Atherosclerosis via the ERK1/2-IRF1-VCAM-1 Pathway., PMID:37957490
Diagnosis of IRAK-4-deficiency by flow cytometric measurement of IκB-α degradation., PMID:37929815
Hepatocyte CYR61 polarizes profibrotic macrophages to orchestrate NASH fibrosis., PMID:37756381
Novel agents in relapsed/refractory diffuse large B-cell lymphoma., PMID:37294966
Paradoxical activation of chronic lymphocytic leukemia cells by ruxolitinib in vitro and in vivo., PMID:37114129
Modulation of expression of proinflammatory genes and humoral immune response following immunization or infection with Aeromonas hydrophila in silver catfish (Rhamdia quelen)., PMID:36419599
Macrophage- and BCR-derived but not TLR-derived signals support the growth of CLL and Richter syndrome murine models in vivo., PMID:36084319
Prevention and partial reversion of the lupus phenotype in ABIN1[D485N] mice by an IRAK4 inhibitor., PMID:34836923
The Interleukin-1 Receptor-Associated Kinase 4 Inhibitor PF-06650833 Blocks Inflammation in Preclinical Models of Rheumatic Disease and in Humans Enrolled in a Randomized Clinical Trial., PMID:34423919
Interleukin-1- Receptor Kinase 4 Inhibition: Achieving Immunomodulatory Synergy to Mitigate the Impact of COVID-19., PMID:34248990
Listeria Monocytogenes Meningoencephalitis Due to IRAK4 Deficiency., PMID:34232442
IgG4-related disease of the orbit in an infant., PMID:34166820
EHA 2021 Virtual Congress., PMID:34153268
Pneumococcal Serotype-specific Opsonophagocytic Activity in Interleukin-1 Receptor-associated Kinase 4-deficient Patients., PMID:33470775
Interleukin-1 Receptor-Associated Kinase 4 Deficiency in a Greek Teenager., PMID:33101742
Interplay and roles of oxidative stress, toll-like receptor 4 and Nrf2 in trichloroethene-mediated autoimmunity., PMID:33007382
B Lymphocytes as Targets of the Immunomodulatory Properties of Human Amniotic Mesenchymal Stromal Cells., PMID:32582218
The regulation and pharmacological modulation of immune complex induced type III IFN production by plasmacytoid dendritic cells., PMID:32503683
Interleukin-1/-33 Signaling Pathways as Therapeutic Targets for Endometriosis., PMID:31507610
TLR7 Protein Expression in Mild and Severe Lupus-Prone Models Is Regulated in a Leukocyte, Genetic, and IRAK4 Dependent Manner., PMID:31354711
Cytokine production by activated plasmacytoid dendritic cells and natural killer cells is suppressed by an IRAK4 inhibitor., PMID:30355354
Antinuclear Antibody-Positive Juvenile Idiopathic Arthritis Despite IRAK-4 Deficiency., PMID:29707745
Clonally expanded γδ T cells protect against Staphylococcus aureus skin reinfection., PMID:29400698
Targeting interferons and their pathways in systemic lupus erythematosus., PMID:29108825
Flow cytometry-based diagnosis of primary immunodeficiency diseases., PMID:28684198
Mmm-derived lipid-associated membrane proteins activate IL-1β production through the NF-κB pathway via TLR2, MyD88, and IRAK4., PMID:28659605
Self-reactive VH4-34-expressing IgG B cells recognize commensal bacteria., PMID:28500047
Deficiency in IRAK4 activity attenuates manifestations of murine Lupus., PMID:28295231
Biophysical Attributes of CpG Presentation Control TLR9 Signaling to Differentially Polarize Systemic Immune Responses., PMID:28099848
Lactobacillus paracasei modulates LPS-induced inflammatory cytokine release by monocyte-macrophages via the up-regulation of negative regulators of NF-kappaB signaling in a TLR2-dependent manner., PMID:28088611
Polydatin ameliorates Staphylococcus aureus-induced mastitis in mice via inhibiting TLR2-mediated activation of the p38 MAPK/NF-κB pathway., PMID:27890916
Dual Inhibition of Rip2 and IRAK1/4 Regulates IL-1β and IL-6 in Sarcoidosis Alveolar Macrophages and Peripheral Blood Mononuclear Cells., PMID:27402699
Selective interleukin-1 receptor-associated kinase 4 inhibitors for the treatment of autoimmune disorders and lymphoid malignancy., PMID:26621451
A benzenediamine derivative fc-99 attenuates lupus-like syndrome in MRL/lpr mice related to suppression of pDC activation., PMID:26545567
PID in Disguise: Molecular Diagnosis of IRAK-4 Deficiency in an Adult Previously Misdiagnosed With Autosomal Dominant Hyper IgE Syndrome., PMID:26472314
The Expression Changes of Inflammasomes in the Aging Rat Kidneys., PMID:26219846
Role of innate immune system in systemic sclerosis., PMID:26159672
Potent and Selective Amidopyrazole Inhibitors of IRAK4 That Are Efficacious in a Rodent Model of Inflammation., PMID:26101573
Immunodeficiency among children with recurrent invasive pneumococcal disease., PMID:25831419
Involvement of DNA-PKcs in the type I IFN response to CpG-ODNs in conventional dendritic cells in TLR9-dependent or -independent manners., PMID:25812014
IRAK-4 and MyD88 deficiencies impair IgM responses against T-independent bacterial antigens., PMID:25320238
The role of interleukin-1 receptor-associated kinases in Vogt-Koyanagi-Harada disease., PMID:24690905
Expression of genes related to anti-inflammatory pathways are modified among farmers' children., PMID:24603716
Fatal pneumococcal meningitis in a 7-year-old girl with interleukin-1 receptor activated kinase deficiency (IRAK-4) despite prophylactic antibiotic and IgG responses to Streptococcus pneumoniae vaccines., PMID:24596024
Interleukin 1/Toll-like receptor-induced autophosphorylation activates interleukin 1 receptor-associated kinase 4 and controls cytokine induction in a cell type-specific manner., PMID:24567333
For research use only. Not for human or drug use.
