Catalog No.
RHJ28501
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
IREM1, Immunoglobulin superfamily member 13, NK inhibitory receptor, CD300 antigen-like family member F, CD300F, CD300LF, CLM-1, IGSF13, NKIR, IREM-1, Immune receptor expressed on myeloid cells 1, CMRF35-like molecule 1, CD300f, IgSF13, CLM1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q8TDQ1
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1608
Intranasal administration of ceramide liposome suppresses allergic rhinitis by targeting CD300f in murine models., PMID:38600251
Targeting CD300f to enhance hematopoietic stem cell transplantation in acute myeloid leukemia., PMID:32215656
CD300f is a potential therapeutic target for the treatment of food allergy., PMID:31471969
CD300f epitopes are specific targets for acute myeloid leukemia with monocytic differentiation., PMID:31338922
Disrupting ceramide-CD300f interaction prevents septic peritonitis by stimulating neutrophil recruitment., PMID:28655892
Ceramide-CD300f Binding Inhibits Lipopolysaccharide-induced Skin Inflammation., PMID:28073916
Enhanced efferocytosis by dendritic cells underlies memory T-cell expansion and susceptibility to autoimmune disease in CD300f-deficient mice., PMID:26768664
CD300f immunoreceptor contributes to peripheral nerve regeneration by the modulation of macrophage inflammatory phenotype., PMID:26259611
CD300f associates with IL-4 receptor α and amplifies IL-4-induced immune cell responses., PMID:26124135
Ceramide-CD300f binding suppresses experimental colitis by inhibiting ATP-mediated mast cell activation., PMID:25673319
The receptor LMIR3 negatively regulates mast cell activation and allergic responses by binding to extracellular ceramide., PMID:23123064
CD300a and CD300f differentially regulate the MyD88 and TRIF-mediated TLR signalling pathways through activation of SHP-1 and/or SHP-2 in human monocytic cell lines., PMID:22043923
CD300F blocks both MyD88 and TRIF-mediated TLR signaling through activation of Src homology region 2 domain-containing phosphatase 1., PMID:21536801
For research use only. Not for human or drug use.
