Catalog No.
RHD27801
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
12LO, 12S-LOX, Arachidonate (12S)-lipoxygenase, Platelet-type lipoxygenase 12, LOG12, Arachidonate (15S)-lipoxygenase, Lipoxin synthase 12-LO, Linoleate (13S)-lipoxygenase, 12S-lipoxygenase, ALOX12, Polyunsaturated fatty acid lipoxygenase ALOX12
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P18054
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1590
CX-5461 ameliorates disease in lupus-prone mice by triggering B-cell ferroptosis via p53-SLC7A11-ALOX12 pathway., PMID:39111584
ALOX12: A Novel Insight in Bevacizumab Response, Immunotherapy Effect, and Prognosis of Colorectal Cancer., PMID:35833141
ω3 fatty acid metabolite, 12-hydroxyeicosapentaenoic acid, alleviates contact hypersensitivity by downregulation of CXCL1 and CXCL2 gene expression in keratinocytes via retinoid X receptor α., PMID:33749892
The peripheral blood transcriptome reflects variations in immunity traits in swine: towards the identification of biomarkers., PMID:24341289
Systematic analysis of rat 12/15-lipoxygenase enzymes reveals critical role for spinal eLOX3 hepoxilin synthase activity in inflammatory hyperalgesia., PMID:23382512
Expression profile of proinflammatory genes in neutrophil-enriched granulocytes stimulated with native anti-PR3 autoantibodies., PMID:22791638