Catalog No.
RHC13301
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
S100 calcium-binding protein A8, Urinary stone protein band A, MRP8, Cystic fibrosis antigen, Calprotectin L1L subunit, MRP-8, p8, Calgranulin-A, Migration inhibitory factor-related protein 8, Leukocyte L1 complex light chain, S100A8, Protein S100-A8, CAGA, CFAG
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P05109
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1556
B7-H3 Exacerbates Laser-induced Choroidal Neovascularization by Promoting Macrophage Recruitment and Polarization via S100A8/A9., PMID:40456216
Synergistic inhibition of CitH3 and S100A8/A9: A novel therapeutic strategy for mitigating sepsis-induced inflammation and lung injury., PMID:40390290
Enhanced Immunity and Infection Resistance in Mice Through Co-Expression of Porcine IL-3, IL-7, and IL-15 Fusion Molecules in Yarrowia lipolytica., PMID:40282231
Reading of human acute immune dynamics in omicron SARS-CoV-2 breakthrough infection., PMID:40231451
Transcriptomic signatures in peripheral CD4+T-lymphocytes may reflect melanoma staging and immunotherapy responsiveness prior to ICI initiation., PMID:40226614
Development of novel neutralizing single-chain fragment variable antibodies against S100A8., PMID:40221535
Extracellular vesicle-bound S100A8/A9 is differentially expressed in septic shock and prompts acute lung injury., PMID:40102943
Highlights from the breakout session: vasculitis in paediatric rheumatology., PMID:40071400
Neutrophil-derived exosomal S100A8 aggravates lung injury in sepsis by inducing pyroptosis., PMID:40056630
Targeting S100A8/A9-NCF1 axis in tumor microenvironment to prevent tumor metastasis by self-assembled peptide nanofibers., PMID:40040282
CD47-blocking antibody interferes with neutrophil extracellular traps formation after spinal cord injury to reduce spinal cord edema., PMID:39951937
An S100A8/A9 Neutralizing Antibody Potently Ameliorates Contact Hypersensitivity and Atopic Dermatitis Symptoms., PMID:39848567
RNF128 deficiency in macrophages promotes colonic inflammation by suppressing the autophagic degradation of S100A8., PMID:39809743
A pan-immune panorama of bacterial pneumonia revealed by a large-scale single-cell transcriptome atlas., PMID:39757231
Novel approaches in myelofibrosis., PMID:39670187
Intraperitoneal Administration of S100A8 Ameliorates Experimental Acute Colitis in Rats., PMID:39596871
Convenient production of a novel recombinant antibody against periodontitis biomarker S100A8., PMID:39564736
Proteomic Analysis of Human Chylomicron Remnants Isolated by Apolipoprotein B-48 Immunoprecipitation., PMID:39085140
Spesolimab Reduces Inflammation in Generalized Pustular Psoriasis: Molecular Characterization of Flare Treatment in EFFISAYIL 1., PMID:39004117
Neutrophil-secreted S100A8/A9 participates in fatty liver injury and fibrosis by promoting myofibroblast migration., PMID:38995368
Intense impact of IL-1β expressing inflammatory macrophages in acute aortic dissection., PMID:38937528
VNN2-expressing circulating monocytes exhibit unique functional characteristics and are decreased in patients with primary Sjögren's syndrome., PMID:38936146
S100 proteins as potential predictive biomarkers of abatacept response in polyarticular juvenile idiopathic arthritis., PMID:38918871
S100a8/9 (S100 Calcium Binding Protein a8/9) Promotes Cardiac Hypertrophy Via Upregulation of FGF23 (Fibroblast Growth Factor 23) in Mice., PMID:38726894
Targeting IL-13 with tralokinumab normalizes type 2 inflammation in atopic dermatitis both early and at 2 years., PMID:38563683
Integrating AI-Powered Digital Pathology and Imaging Mass Cytometry Identifies Key Classifiers of Tumor Cells, Stroma, and Immune Cells in Non-Small Cell Lung Cancer., PMID:38315789
Longitudinal plasma proteome profiling reveals the diversity of biomarkers for diagnosis and cetuximab therapy response of colorectal cancer., PMID:38302471
Generation and Application of Monoclonal Antibodies against Porcine S100A8, S100A9, and S100A12 Proteins Using Hybridoma Technology., PMID:38256103
Calprotectin Impairs Platelet Survival in Patients With Primary Antiphospholipid Syndrome., PMID:38225923
Inhibiting anti-angiogenic VEGF165b activates a miR-17-20a-Calcipressin-3 pathway that revascularizes ischemic muscle in peripheral artery disease., PMID:38182796
Tim-3 deficiency aggravates cadmium nephrotoxicity via regulation of NF-κB signaling and mitochondrial damage., PMID:38176346
AIM/CD5L ameliorates autoimmune arthritis by promoting removal of inflammatory DAMPs at the lesions., PMID:38006711
A pro-inflammatory gut mucosal cytokine response is associated with mild COVID-19 disease and superior induction of serum antibodies., PMID:37995912
Viral nanoparticle vaccines against S100A9 reduce lung tumor seeding and metastasis., PMID:37844250
The Qi Yin San Liang San decoction enhances anti-CD19 CAR-T cell function in the treatment of B-cell lymphomas., PMID:37657771
Inhibiting Anti-angiogenic VEGF165b Activates a Novel miR-17-20a-Calcipressin-3 Pathway that Revascularizes Ischemic Muscle in Peripheral Artery Disease., PMID:37645966
BTK inhibition potentiates anti-PD-L1 treatment in murine melanoma: potential role for MDSC modulation in immunotherapy., PMID:37528320
Single-cell multi-omics sequencing reveals the immunological disturbance underlying STAT3-V637M Hyper-IgE syndrome., PMID:37480751
Role of innate immunological/inflammatory pathways in myelodysplastic syndromes and AML: a narrative review., PMID:37422676
Circulating neutrophils activated by cancer cells and M2 macrophages promote gastric cancer progression during PD-1 antibody-based immunotherapy., PMID:37333017
Molecular Signatures in Swine Innate and Adaptive Immune Responses to African Swine Fever Virus Antigens p30/p54/CD2v Expressed Using a Highly Efficient Semliki Forest Virus Replicon System., PMID:37298266
Socs3 expression in myeloid cells modulates the pathogenesis of dextran sulfate sodium (DSS)-induced colitis., PMID:37283760
Unraveling CD69 signaling pathways, ligands and laterally associated molecules., PMID:37223078
Discovery and systematic assessment of early biomarkers that predict progression to severe COVID-19 disease., PMID:37041310
Targeted Transcriptional Analysis of IgA Vasculitis, IgA Nephropathy, and IgA-Dominant Infection-Related Glomerulonephritis Reveals Both Distinct and Overlapping Immune Signatures., PMID:37036681
Topical emollient prevents the development of atopic dermatitis and atopic march in mice., PMID:37029953
Desmoglein-Specific B-Cell-Targeted Single-Cell Analysis Revealing Unique Gene Regulation in Patients with Pemphigus., PMID:36997112
Generation of a novel monoclonal antibody against inflammatory biomarker S100A8 using hybridoma technology., PMID:36971774
Novel multivalent S100A8 inhibitory peptides attenuate tumor progression and metastasis by inhibiting the TLR4-dependent pathway., PMID:36932197
Intensive cholesterol-lowering treatment reduces synovial inflammation during early collagenase-induced osteoarthritis, but not pathology at end-stage disease in female dyslipidemic E3L.CETP mice., PMID:36898656
For research use only. Not for human or drug use.
