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Anti-Human LRG1 Antibody (SAA1550)

Catalog #:   RHC00701 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA
Accession: P02750
Overview

Catalog No.

RHC00701

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

LRG1, LRG, Leucine-rich alpha-2-glycoprotein

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P02750

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1550

Data Image
References

Development of a novel histidine-rich glycoprotein measurement system as a biomarker for sepsis., PMID:40324742

LRG1 Alters Pericyte Phenotype and Compromises Vascular Maturation., PMID:40277918

LRG1 inhibition promotes acute pancreatitis recovery by inducing cholecystokinin Type 1 receptor expression via Akt., PMID:40225588

Biological signatures in the Alzheimer's continuum discriminate between diagnosis-related and -unrelated associations to ATN categories., PMID:40046342

Selection of anti-cytokine biologics by pretreatment levels of serum leucine-rich alpha-2 glycoprotein in patients with inflammatory bowel disease., PMID:39613813

Diet-enhanced LRG1 expression promotes insulin hypersecretion and ER stress in pancreatic beta cells., PMID:39589509

Clinical Profiles of Leucine-Rich Alpha-2 Glycoprotein for Indicating Mucosal Healing in Ulcerative Colitis Patients under Administration of Molecular-Targeted Drug., PMID:39462503

Leucine-Rich Alpha-2-Glycoprotein 1 Promotes Metastatic Colorectal Cancer Growth Through Human Epidermal Growth Factor Receptor 3 Signaling., PMID:39393543

LRG1 promotes atherosclerosis by inducing macrophage M1-like polarization., PMID:39178231

Targeting Gsk3a reverses immune evasion to enhance immunotherapy in hepatocellular carcinoma., PMID:39174053

Activated platelet-derived exosomal LRG1 promotes multiple myeloma cell growth., PMID:38871685

The disruptive role of LRG1 on the vasculature and perivascular microenvironment., PMID:38745756

Leucine-rich alpha-2-glycoprotein 1 affects bone destruction via IL-6 in mouse periodontitis model., PMID:38656694

Integrated plasma proteomics identifies tuberculosis-specific diagnostic biomarkers., PMID:38512356

High serum levels of leucine-rich α-2 glycoprotein 1 (LRG-1) are associated with poor survival in patients with early breast cancer., PMID:38413424

Mechanisms of blood-retinal barrier disruption related to intraocular inflammation and malignancy., PMID:38242492

Biomarkers in the Pathogenesis, Diagnosis, and Treatment of Systemic Sclerosis., PMID:37868834

A new method for screening acute/chronic lymphocytic leukemia: dual-label time-resolved fluorescence immunoassay., PMID:36180909

An Immunological Axis Involving Interleukin 1β and Leucine-Rich-α2-Glycoprotein Reflects Therapeutic Response of Children with Kawasaki Disease: Implications from the KAWAKINRA Trial., PMID:35699824

Structural basis of human LRG1 recognition by Magacizumab, a humanized monoclonal antibody with therapeutic potential., PMID:35647920

LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency., PMID:35590198

Angiopathic activity of LRG1 is induced by the IL-6/STAT3 pathway., PMID:35318338

A novel strategy for identifying biomarker in serum of patient with COVID-19 using immune complex., PMID:35228518

LRG1: an emerging player in disease pathogenesis., PMID:35062948

LRG1 as a novel therapeutic target in eye disease., PMID:34987199

Detection of leucine-rich alpha-2-glycoprotein 1 containing immunocomplexes in the plasma of lung cancer patients with epitope-specific mAbs., PMID:34744074

Paradoxical Roles of Leucine-Rich α2-Glycoprotein-1 in Cell Death and Survival Modulated by Transforming Growth Factor-Beta 1 and Cytochrome c., PMID:34692699

Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis., PMID:34516824

Risk-Predictive and Diagnostic Biomarkers for Colorectal Cancer; a Systematic Review of Studies Using Pre-Diagnostic Blood Samples Collected in Prospective Cohorts and Screening Settings., PMID:34503217

Leucine-rich alpha-2-glycoprotein 1 and angiotensinogen as diagnostic biomarkers for Kawasaki disease., PMID:34499692

Leucine-rich alpha-2-glycoprotein 1 (LRG1) as a novel ADC target., PMID:34458833

Comprehensive analysis of protein-expression changes specific to immunoglobulin G4-related disease., PMID:34453919

LRG1 Expression Is Elevated in the Eyes of Patients with Neovascular Age-Related Macular Degeneration., PMID:34445590

Distinct Gene Expression Signatures Characterize Strong Clinical Responders Versus Nonresponders to Canakinumab in Children With Systemic Juvenile Idiopathic Arthritis., PMID:33452871

Intracellular leucine-rich alpha-2-glycoprotein-1 competes with Apaf-1 for binding cytochrome c in protecting MCF-7 breast cancer cells from apoptosis., PMID:33386492

Correlation of increased serum leucine-rich α2-glycoprotein levels with disease prognosis, progression, and activity of interstitial pneumonia in patients with dermatomyositis: A retrospective study., PMID:32479560

Protein Network Analysis Identifies Changes in the Level of Proteins Involved in Platelet Degranulation, Proteolysis and Cholesterol Metabolism Pathways in AECOPD Patients., PMID:31920121

Proteins in stool as biomarkers for non-invasive detection of colorectal adenomas with high risk of progression., PMID:31784980

Human induced pluripotent stem cell-derived mesenchymal stem cells promote healing via TNF-α-stimulated gene-6 in inflammatory bowel disease models., PMID:31558705

Serum proteomics analysis based on label-free revealed the protective effect of Chinese herbal formula Gu-Ben-Fang-Xiao., PMID:31520916

Leucine-Rich α-2-Glycoprotein-1 (LRG-1) Expression in Retinoblastoma., PMID:29392314

[Not Available]., PMID:29176291

Leucine-rich α2-glycoprotein as the acute-phase reactant to detect systemic juvenile idiopathic arthritis disease activity during anti-interleukin-6 blockade therapy: A case series., PMID:28094589

Sputum Leucine-Rich Alpha-2 Glycoprotein as a Marker of Airway Inflammation in Asthma., PMID:27611322

Myeloid cell-derived LRG attenuates adverse cardiac remodelling after myocardial infarction., PMID:26678356

Discovery and Validation of Predictive Biomarkers of Survival for Non-small Cell Lung Cancer Patients Undergoing Radical Radiotherapy: Two Proteins With Predictive Value., PMID:26425690

Identification of urine protein biomarkers with the potential for early detection of lung cancer., PMID:26133466

Leucine-rich α2 -glycoprotein as a potential biomarker for joint inflammation during anti-interleukin-6 biologic therapy in rheumatoid arthritis., PMID:25917892

LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling., PMID:23868260

Serum protein profile of Crohn's disease treated with infliximab., PMID:23562004

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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Anti-Human LRG1 Antibody (SAA1550) [RHC00701]
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