Catalog No.
RHC92401
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Collagen alpha-3(VI) chain, COL6A3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P12111
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1530
The UCMD-Causing COL6A1 (c.930 + 189C > T) Intron Mutation Leads to the Secretion and Aggregation of Single Mutated Collagen VI α1 Chains., PMID:40225172
High levels of intracellular endotrophin in adipocytes mediate COPII vesicle supplies to autophagosome to impair autophagic flux and contribute to systemic insulin resistance in obesity., PMID:37302692
Plasma Proteomics Unveil Novel Immune Signatures and Biomarkers upon SARS-CoV-2 Infection., PMID:37047248
LMCD1 antisense RNA 1 is a newly identified long noncoding RNA., PMID:34232945
Circular RNA hsa_circ_0006401 promotes proliferation and metastasis in colorectal carcinoma., PMID:33947841
A Fragment of Collagen Type VI alpha-3 chain is Elevated in Serum from Patients with Gastrointestinal Disorders., PMID:32245981
Complexity in unclassified auto-inflammatory disease: a case report illustrating the potential for disease arising from the allelic burden of multiple variants., PMID:31660995
Human endotrophin as a driver of malignant tumor growth., PMID:30896449
COL6A3-derived endotrophin links reciprocal interactions among hepatic cells in the pathology of chronic liver disease., PMID:30246318
Authentication of collagen VI antibodies., PMID:28755659
Inhibition of endotrophin, a cleavage product of collagen VI, confers cisplatin sensitivity to tumours., PMID:23629957
Expression of collagen VI α5 and α6 chains in human muscle and in Duchenne muscular dystrophy-related muscle fibrosis., PMID:22226732
Expression of the collagen VI α5 and α6 chains in normal human skin and in skin of patients with collagen VI-related myopathies., PMID:20882040
Immunohistochemical and biogenetic features of diffuse-type tenosynovial giant cell tumors: the potential roles of cyclin A, P53, and deletion of 15q in sarcomatous transformation., PMID:18829481
A refined diagnostic algorithm for Bethlem myopathy., PMID:18378883
The congenital muscular dystrophies: recent advances and molecular insights., PMID:17163796
Remodeling of the extracellular matrix through overexpression of collagen VI contributes to cisplatin resistance in ovarian cancer cells., PMID:12726863
Mutations in COL6A3 cause severe and mild phenotypes of Ullrich congenital muscular dystrophy., PMID:11992252
The C5 domain of Col6A3 is cleaved off from the Col6 fibrils immediately after secretion., PMID:11785962
Morphological classification of nuchal skin in human fetuses with trisomy 21, 18, and 13 at 12-18 weeks and in a trisomy 16 mouse., PMID:9497154