Catalog No.
RHB03701
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
CRLR activity-modifying protein 2, RAMP2, Calcitonin-receptor-like receptor activity-modifying protein 2, Receptor activity-modifying protein 2
Concentration
1.07 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O60895
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1521
Receptor activity-modifying protein modulation of parathyroid hormone-1 receptor function and signaling., PMID:39376604
Balance of Gata3 and Ramp2 in hepatocytes regulates hepatic vascular reconstitution in postoperative liver regeneration., PMID:37918568
Adrenomedullin Secreted by Melanoma Cells Promotes Melanoma Tumor Growth through Angiogenesis and Lymphangiogenesis., PMID:36497391
Modulation of osteoclastogenesis through adrenomedullin receptors on osteoclast precursors: initiation of differentiation by asymmetric cell division., PMID:34611305
Expression of the CGRP Family of Neuropeptides and their Receptors in the Trigeminal Ganglion., PMID:32086679
Development of chimeric and bifunctional antagonists for CLR/RAMP receptors., PMID:31150417
Is the activity of CGRP and Adrenomedullin regulated by RAMP (-2) and (-3) in Trypanosomatidae? An in-silico approach., PMID:29626675
Stromal fibroblasts present in breast carcinomas promote tumor growth and angiogenesis through adrenomedullin secretion., PMID:28178651
Functional Analysis of the Adrenomedullin Pathway in Malignant Pleural Mesothelioma., PMID:26762744
[Adrenomedullin-Receptor Activity-modifying Protein 2 (RAMP2) System in Retinal Angiogenesis]., PMID:26685480
Adrenomedullin blockade suppresses growth of human hormone-independent prostate tumor xenograft in mice., PMID:24100627
Expression of adrenomedullin in human colorectal tumors and its role in cell growth and invasion in vitro and in xenograft growth in vivo., PMID:23634287
Adrenomedullin-RAMP2 system is crucially involved in retinal angiogenesis., PMID:23562442
An angiogenic role for adrenomedullin in choroidal neovascularization., PMID:23520487
Intermedin stabilized endothelial barrier function and attenuated ventilator-induced lung injury in mice., PMID:22563471
Targeting adrenomedullin receptors with systemic delivery of neutralizing antibodies inhibits tumor angiogenesis and suppresses growth of human tumor xenografts in mice., PMID:19546305
Intermedin 1-53 inhibits rat cardiac fibroblast activation induced by angiotensin II., PMID:19523990
Identification of N-terminal receptor activity-modifying protein residues important for calcitonin gene-related peptide, adrenomedullin, and amylin receptor function., PMID:18593822
Calcitonin receptor-like receptor and receptor activity modifying protein 1 in the rat dorsal horn: localization in glutamatergic presynaptic terminals containing opioids and adrenergic alpha2C receptors., PMID:17614212
Adrenomedullin increases the expression of calcitonin-like receptor and receptor activity modifying protein 2 mRNA in human microvascular endothelial cells., PMID:16899583
Localization of calcitonin receptor-like receptor and receptor activity modifying protein 1 in enteric neurons, dorsal root ganglia, and the spinal cord of the rat., PMID:16082677
[Role of adrenomedullin in glioblastomas growth]., PMID:15888388
Effects of adrenomedullin on endothelial cells in the multistep process of angiogenesis: involvement of CRLR/RAMP2 and CRLR/RAMP3 receptors., PMID:14712479
Over-expression of wild-type and mutant HFE in a human melanocytic cell line reveals an intracellular bridge between MHC class I pathway and transferrin iron uptake., PMID:12941522
Expression and distribution of the calcitonin receptor-like receptor in the developing rat heart., PMID:12937976
Adrenomedullin is an autocrine/paracrine growth factor for rat vascular smooth muscle cells., PMID:12667639
Comparison of the expression of calcitonin receptor-like receptor (CRLR) and receptor activity modifying proteins (RAMPs) with CGRP and adrenomedullin binding in cell lines., PMID:12086988
Neutralization of adrenomedullin inhibits the growth of human glioblastoma cell lines in vitro and suppresses tumor xenograft growth in vivo., PMID:11943713
Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling., PMID:10882736
For research use only. Not for human or drug use.
