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Anti-Human TMEFF2 Antibody (SAA1493)

Catalog #:   RHJ77701 Specific References (12) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA
Accession: Q9UIK5
Overview

Catalog No.

RHJ77701

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

Transmembrane protein with EGF-like and two follistatin-like domains, TENB2, Hyperplastic polyposis protein 1, TR-2, HPP1, TMEFF2, TPEF, Tomoregulin-2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9UIK5

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1493

Data Image
References

A first-in-human study of JNJ-70218902, a bispecific T-cell-redirecting antibody against TMEFF2 in metastatic castration-resistant prostate cancer., PMID:39832129

Methylated free-circulating HPP1 DNA is an early response marker in patients with metastatic colorectal cancer., PMID:28124380

ImmunoPET helps predicting the efficacy of antibody-drug conjugates targeting TENB2 and STEAP1., PMID:27029064

Tomoregulin (TMEFF2) Binds Alzheimer's Disease Amyloid-β (Aβ) Oligomer and AβPP and Protects Neurons from Aβ-Induced Toxicity., PMID:26402097

The TMEFF2 tumor suppressor modulates integrin expression, RhoA activation and migration of prostate cancer cells., PMID:24632071

Anti-tumor efficacy of chitosan-g-poly(ethylene glycol) nanocapsules containing docetaxel: anti-TMEFF-2 functionalized nanocapsules vs. non-functionalized nanocapsules., PMID:23262164

An integrated approach to identify normal tissue expression of targets for antibody-drug conjugates: case study of TENB2., PMID:22889168

Differential effects of predosing on tumor and tissue uptake of an 111In-labeled anti-TENB2 antibody-drug conjugate., PMID:22872740

Obligate multivalent recognition of cell surface tomoregulin following selection from a multivalent phage antibody library., PMID:17092910

Induction of apoptosis in hematopoietic cells with an antibody against tomoregulin-1., PMID:16475715

Targeting tomoregulin for radioimmunotherapy of prostate cancer., PMID:15805286

Preclinical validation of anti-TMEFF2-auristatin E-conjugated antibodies in the treatment of prostate cancer., PMID:15299075

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human TMEFF2 Antibody (SAA1493) [RHJ77701]
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