Catalog No.
YMN00301
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Met44-Cys287
Predicted molecular weight
30.57 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
A2AKW8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NTNG2, KIAA1857, Laminet-2, Netrin-G2, LMNT2
Compound heterozygous mutations of NTNG2 cause intellectual disability via inhibition of the CaMKII signaling., PMID:39151821
ISL1 and POU4F1 Directly Interact to Regulate the Differentiation and Survival of Inner Ear Sensory Neurons., PMID:38267260
Effects of cylindrospermopsin, chlorpyrifos and their combination in a SH-SY5Y cell model concerning developmental neurotoxicity., PMID:38091671
Single-Nucleus Transcriptional Profiling of GAD2-Positive Neurons From Mouse Lateral Habenula Reveals Distinct Expression of Neurotransmission- and Depression-Related Genes., PMID:37881543
Single-nucleus transcriptional profiling of GAD2-positive neurons from mouse lateral habenula reveals distinct expression of neurotransmission- and depression-related genes., PMID:36711842
Autistic-like behavior and cerebellar dysfunction in Bmal1 mutant mice ameliorated by mTORC1 inhibition., PMID:35301425
Prognostic and Immune-Infiltrate Significance of miR-222-3p and Its Target Genes in Thyroid Cancer., PMID:34737762
Objective detection of microtremors in netrin-G2 knockout mice., PMID:33450333
The pan-cancer landscape of netrin family reveals potential oncogenic biomarkers., PMID:32251318
Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies., PMID:32109663
Netrin-G2 dysfunction causes a Rett-like phenotype with areflexia., PMID:31692205
Homozygous Missense Variants in NTNG2, Encoding a Presynaptic Netrin-G2 Adhesion Protein, Lead to a Distinct Neurodevelopmental Disorder., PMID:31668703
Homozygous frameshift variant in NTNG2, encoding a synaptic cell adhesion molecule, in individuals with developmental delay, hypotonia, and autistic features., PMID:31372774
Locomotor Training Increases Synaptic Structure With High NGL-2 Expression After Spinal Cord Hemisection., PMID:30782076
Association between miRNAs expression and cognitive performances of Pediatric Multiple Sclerosis patients: A pilot study., PMID:30656857
Axon Terminal Arbors of Retinal Horizontal Cells Lose Control., PMID:30364242
Somatic mutations in specific and connected subpathways are associated with short neuroblastoma patients' survival and indicate proteins targetable at onset of disease., PMID:29992558
Functional expression of BMP7 receptors in oral epithelial cells. Interleukin-17F production in response to BMP7., PMID:28812969
Patient Mutations of the Intellectual Disability Gene KDM5C Downregulate Netrin G2 and Suppress Neurite Growth in Neuro2a Cells., PMID:27421841
Impacts of Salmonella enterica Serovar Typhimurium and Its speG Gene on the Transcriptomes of In Vitro M Cells and Caco-2 Cells., PMID:27064787
Diversification of behavior and postsynaptic properties by netrin-G presynaptic adhesion family proteins., PMID:26746425
Integrin-linked kinase regulates oligodendrocyte cytoskeleton, growth cone, and adhesion dynamics., PMID:26614167
NGL-2 Is a New Partner of PAR Complex in Axon Differentiation., PMID:25948265
Netrin-G/NGL complexes encode functional synaptic diversification., PMID:25411505
Identification of transcriptional regulatory elements for Ntng1 and Ntng2 genes in mice., PMID:24642214
Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality., PMID:24441682
NGL-2 regulates pathway-specific neurite growth and lamination, synapse formation, and signal transmission in the retina., PMID:23864682
Robust structural analysis of native biological macromolecules from multi-crystal anomalous diffraction data., PMID:23793158
Topography of Gng2- and NetrinG2-expression suggests an insular origin of the human claustrum., PMID:22957104
The AChE membrane-binding tail PRiMA is down-regulated in muscle and nerve of mice with muscular dystrophy by merosin deficiency., PMID:22906800
Structures from anomalous diffraction of native biological macromolecules., PMID:22628655
The clasp between NetrinG and NGL becomes crystal clear., PMID:22048335
Crystal structure of the ligand binding domain of netrin G2., PMID:22041449
Structural basis for cell surface patterning through NetrinG-NGL interactions., PMID:21946559
Netrin G-2 ligand mRNA is downregulated in spinal motoneurons after sciatic nerve lesion., PMID:20577133
Abnormal expression of netrin-G2 in temporal lobe epilepsy neurons in humans and a rat model., PMID:20382146
Markers of glutamate synaptic transmission and plasticity are increased in the anterior cingulate cortex in bipolar disorder., PMID:20079890
Gelsolin is required for macrophage recruitment during remyelination of the peripheral nervous system., PMID:20014276
Netrin-G2 and netrin-G2 ligand are both required for normal auditory responsiveness., PMID:17973922
Axonal netrin-Gs transneuronally determine lamina-specific subdendritic segments., PMID:17785411
Decreased mRNA expression of netrin-G1 and netrin-G2 in the temporal lobe in schizophrenia and bipolar disorder., PMID:17507910
Cytoplasmic gamma-actin expression in diverse animal models of muscular dystrophy., PMID:17475492
Human netrin-G1 isoforms show evidence of differential expression., PMID:15901489
A family-based association study and gene expression analyses of netrin-G1 and -G2 genes in schizophrenia., PMID:15705354
The congenital muscular dystrophies in 2004: a century of exciting progress., PMID:15351421
Laminets: laminin- and netrin-related genes expressed in distinct neuronal subsets., PMID:11906208
Complementary expression and neurite outgrowth activity of netrin-G subfamily members., PMID:11804778
For research use only. Not for human or drug use.
