Catalog No.
YMJ05201
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Glu25-Asn116
Predicted molecular weight
23.15 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Z1N6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
sFRP-4, FRP-4, Secreted frizzled-related sequence protein 4, Sfrp4
The prognostic and immune significance of fibronectin type III domain-containing 1 gene in pan-cancer and its relationship with proliferation and migration of stomach adenocarcinoma., PMID:40530118
Epigenetics and Expression of the Wnt Signaling Pathway in Ulcerative Colitis., PMID:40521787
Premature cell senescence promotes vascular smooth muscle cell phenotypic modulation and resistance to re-differentiation., PMID:40493738
Evolutionary and Structural Assessment of the Human Secreted Frizzled-Related Protein (SFRP) Family., PMID:40372458
Autophagy-mediated regulation of psoriasis biomarkers by Dead Sea and magnetized saline waters: An in vitro study., PMID:40319456
Effect of resveratrol and quercetin on SFRP4 as a biomarker of diabesity: In silico and in vivo studies., PMID:40194339
Unveiling mechanisms underlying kidney function changes during sex hormone therapy., PMID:40193283
Comprehensive bioinformatics analysis of hub genes in ischemic heart failure and atrial fibrillation., PMID:40066352
SFRP4 Knockdown Attenuates Dsg2-Deficient Arrhythmogenic Cardiomyopathy by Down-Regulating TGF-β and Smad3., PMID:40019607
Analysis of thyroid carcinoma composition and spatial architecture in the progression of dedifferentiation, lymphatic metastasis, and gastric metastasis., PMID:39984992
A novel function of the Wnt antagonist secreted frizzled-related protein 4 as a transcriptional regulator of Dickkopf-1, another Wnt antagonist, in glioblastoma cell line U87MG., PMID:39938692
Non-canonical Wnt signaling pathway activated NFATC3 promotes GDF15 expression in MASH: prospective analyses of UK biobank proteomic data., PMID:39836348
Expression, prognosis, immunological infiltration, and DNA methylation of members of the SFRP gene family in colorectal cancer: a comparative bioinformatic and experimental analysis., PMID:39729237
Disturbed Spatial WNT Activation-A Potential Driver of the Reticularized Skin Phenotype in Systemic Sclerosis., PMID:39722197
Roles of osteoclasts in pathological conditions., PMID:39704061
Spatial transcriptomics reveals strong association between SFRP4 and extracellular matrix remodeling in prostate cancer., PMID:39511287
Exploring the predictive values of SERP4 and FRZB in dilated cardiomyopathy based on an integrated analysis., PMID:39425025
Multi-omic analyses identified SFRP4 as a novel biomarker in abnormal uterine bleeding with ovulatory dysfunction., PMID:39286067
SFRP4 contributes to insulin resistance-induced polycystic ovary syndrome by triggering ovarian granulosa cell hyperandrogenism and apoptosis through the nuclear β-catenin/IL-6 signaling axis., PMID:39159685
SFRP4 promotes autophagy and blunts FSH responsiveness through inhibition of AKT signaling in ovarian granulosa cells., PMID:39138534
Proliferative arrest induces neuronal differentiation and innate immune responses in normal and Creutzfeldt-Jakob Disease agent (CJ) infected rat septal neurons., PMID:39131355
Exome-wide association study identifies KDELR3 mutations in extreme myopia., PMID:39112444
Screening of Secretory Proteins Linking Major Depressive Disorder with Heart Failure Based on Comprehensive Bioinformatics Analysis and Machine Learning., PMID:39062507
Dynamic Transcriptome Analysis of SFRP Family in Guided Bone Regeneration With Occlusive Periosteum in Swine Model., PMID:39042069
[Mechanism of Huangqin Qingre Chubi Capsules in improving rheumatoid arthritis based on METTL3-SFRP4/Wnt/β-catenin pathway]., PMID:39041168
Normoglycemia and type 2 diabetes: exploring secreted frizzled-4, insulin resistance, and waist-height ratio., PMID:39028066
SFRP4 protein expression is reduced in high grade astrocytomas which is not caused by the methylation of its promoter., PMID:38993819
Comprehensive transcriptome profiling between balding and non-balding scalp of female pattern hair loss in Asian., PMID:38850442
Role of secreted frizzled-related protein 4 in prediabetes and type 2 diabetes: a cross sectional study., PMID:38834984
Role of secreted frizzled-related protein 5 in granulosa cells of hu sheep ovaries., PMID:38805996
Cord Blood Proteomic Profiles, Birth Weight, and Early Life Growth Trajectories., PMID:38743419
New treatment strategies for uterine sarcoma using secreted frizzled‑related proteins., PMID:38628655
17 variants interaction of Wnt/β-catenin pathway associated with development of osteonecrosis of femoral head in Chinese Han population., PMID:38538713
Soluble Frizzled-related proteins promote exosome-mediated Wnt re-secretion., PMID:38429359
JMJD2A mediates transcriptional activation of SFRP4 and regulates oxidative stress and mitochondrial dysfunction in heart failure., PMID:38411359
Identifying OGN as a Biomarker Covering Multiple Pathogenic Pathways for Diagnosing Heart Failure: From Machine Learning to Mechanism Interpretation., PMID:38397416
Identification of Fibroinflammatory and Fibrotic Transcriptomic Subsets of Human Cutaneous Sclerotic Chronic Graft-Versus-Host Disease., PMID:38357212
Proteomic detection of COX-2 pathway-related factors in patients with adenomyosis., PMID:38239300
Expression of secreted frizzled-related proteins in acute aortic dissection patients and the effects on prognosis., PMID:38188253
Characterization of Wnt signaling pathway under treatment of Lactobacillus acidophilus postbiotic in colorectal cancer using an integrated in silico and in vitro analysis., PMID:38151510
RUNX2-related metaphyseal dysplasia with maxillary hypoplasia: A rare skeletal disorder resembling SFRP4-related Pyle disease., PMID:38108099
Secreted Frizzled-Related Protein 4 Induces Gastric Cancer Progression and Resistance to Cisplatin and Oxaliplatin via β-Catenin Dysregulation., PMID:38071975
Danggui Buxue Decoction exerts its therapeutic effect on rheumatoid arthritis through the inhibition of Wnt/β-catenin signaling pathway., PMID:38066567
Circadian gene Per3 promotes astroblastoma progression through the P53/BCL2/BAX signalling pathway., PMID:37951372
In Silico identification of novel phytochemicals that target SFRP4: An early biomarker of diabesity., PMID:37943820
Sfrp4 is required to maintain Ctsk-lineage periosteal stem cell niche function., PMID:37931101
Alterations in SAMD9, AHSG, FRG2C, and FGFR4 Genes in a Case of Late-Onset Massive Tumoral Calcinosis., PMID:37736313
iPSC-Derived Glioblastoma Cells Have Enhanced Stemness Wnt/β-Catenin Activity Which Is Negatively Regulated by Wnt Antagonist sFRP4., PMID:37509281
Ghrelin promotes cardiomyocyte differentiation of adipose tissue‑derived mesenchymal stem cells by DDX17‑mediated regulation of the SFRP4/Wnt/β‑catenin axis., PMID:37449526
Identifying immune cell infiltration and diagnostic biomarkers in heart failure and osteoarthritis by bioinformatics analysis., PMID:37390254
For research use only. Not for human or drug use.
