Catalog No.
YMK99101
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Thr32-Ile237
Predicted molecular weight
25.96 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
A4QPC6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Butyrophilin subfamily 2 member A2, Btn2a2
An antibody targeting an immune checkpoint molecule BTN2A2 enhances anti-tumor immunity., PMID:40262436
A Ménage à trois: NLRC5, immunity, and metabolism., PMID:39035010
BTN2A2, a new biomarker and therapeutic target for glioma., PMID:37851374
Frameshift mutations of immunomodulatory BTN2A1, BTN2A2, and BTNL3 genes in colon cancers., PMID:37634314
BTN2A2-Ig protein inhibits the differentiation of pathogenic Th17 cells and attenuates EAE in mice., PMID:37369312
Butyrophilin 2a2 (Btn2a2) expression on thymic epithelial cells promotes central T cell tolerance and prevents autoimmune disease., PMID:37356345
Btn2a2 Regulates ILC2-T Cell Cross Talk in Type 2 Immune Responses., PMID:35145516
BTN2A2 protein negatively regulates T cells to ameliorate collagen-induced arthritis in mice., PMID:34588505
RANKL-Induced Btn2a2 - A T Cell Immunomodulatory Molecule - During Osteoclast Differentiation Fine-Tunes Bone Resorption., PMID:34421818
Prognostic value of immune checkpoint molecules in breast cancer., PMID:32602545
Hypoxia leads to significant changes in alternative splicing and elevated expression of CLK splice factor kinases in PC3 prostate cancer cells., PMID:29606096
Altered expression of Butyrophilin (BTN) and BTN-like (BTNL) genes in intestinal inflammation and colon cancer., PMID:27957327
Gene-Based Genome-Wide Association Analysis in European and Asian Populations Identified Novel Genes for Rheumatoid Arthritis., PMID:27898717
Btn2a2, a T cell immunomodulatory molecule coregulated with MHC class II genes., PMID:26809444
Butyrophilin Btn2a2 inhibits TCR activation and phosphatidylinositol 3-kinase/Akt pathway signaling and induces Foxp3 expression in T lymphocytes., PMID:23589618
BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation., PMID:20208008
A proteomic approach to evaluate the butyrophilin gene family expression in human milk fat globule membrane., PMID:12124930
For research use only. Not for human or drug use.
