Catalog No.
YMD29701
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Arg8-Gln159
Predicted molecular weight
19.63 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q542W1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Interleukin-1 receptor antagonist protein, IL1 inhibitor, IL1RN, IL-1ra, IL-1RN, Anakinra, IL1RA, IL1F3, IRAP, ICIL-1RA
Dissecting the shared molecular mechanisms underlying polycystic ovary syndrome and schizophrenia etiology: a translational integrative approach., PMID:40387450
Dynamic immune response to Avian Pathogenic Escherichia coli infection in broiler chickens: Insights into pro-inflammatory and anti-inflammatory cytokine regulation: CYTOKINE REGULATION IN APEC INFECTED BROILERS., PMID:40220487
Bioinformatics identification and validation of pyroptosis-related gene for ischemic stroke., PMID:40091022
Identification of two biological subgroups of complex regional pain syndrome type 1 by transcriptomic profiling of skin and blood in women., PMID:40075262
Identifying Circulating Protein Mediators in the Link Between Smoking and Abdominal Aortic Aneurysm: An Integrated Analysis of Human Proteomic and Genomic Data., PMID:40061319
Comprehensive transcriptomics analysis of peripheral blood mononuclear cells in exposure to mustard gas., PMID:39946765
Single-Cell Landscape of Bronchoalveolar Lavage Fluid Identifies Specific Neutrophils during Septic Immunosuppression., PMID:39887584
Association of Variants in IL-1RN (rs2234663) and IL-1β (rs1143627, rs16944) and Interleukin-1β Levels with Colorectal Cancer: Experimental Study and In Silico Analysis., PMID:39766795
Maternal characteristics are associated with human milk anti-inflammatory proteins in two populations., PMID:39730549
α7-Nicotinic Acetylcholine Receptor Activation Modulates BV2 Microglial Plasticity via miR-21/TNF-α/NFκB in Oxygen-Glucose Deprivation/Reoxygenation., PMID:39718716
Pulsed Red Photobiomodulation Boosts the Inhibition of Oxytocin-Induced Primary Dysmenorrhea in Mice by Suppressing Oxidative Stress and Inflammation., PMID:39676335
Bioinformatics analysis reveals potential crosstalk genes and molecular mechanisms between ulcerative colitis and psoriasis., PMID:39673621
Correlation of IL-10 and IL18 with the development of liver cirrhosis associated with hepatitis B virus infection: A systematic review., PMID:39671883
The synergistic effect of pulsed red light and leonurus inhibits primary dysmenorrhea induced by oxytocin in mice by modulating calcium signaling and inhibiting inflammatory responses., PMID:39662253
Development and Optimization of a Redox Enzyme-Based Fluorescence Biosensor for the Identification of MsrB1 Inhibitors., PMID:39594490
Unveiling the impact of C15orf48 on non-small cell lung cancer through NF-kappa B signaling., PMID:39576886
PCRX-201, a novel IL-1Ra gene therapy treatment approach for low back pain resulting from intervertebral disc degeneration., PMID:39572769
Gout-associated SNP at the IL1RN-IL1F10 region is associated with altered cytokine production in PBMCs of patients with gout and controls., PMID:39568029
Association of IL1RN VNTR and NKG2A polymorphisms with hepatitis E infection, a case study from western India., PMID:39560779
Single-cell transcriptomics unveils skin cell specific antifungal immune responses and IL-1Ra- IL-1R immune evasion strategies of emerging fungal pathogen Candida auris., PMID:39536069
Exosomes from polarized Microglia: Proteomic insights into potential mechanisms affecting intracerebral hemorrhage., PMID:39510328
Engineered self-regulating macrophages for targeted anti-inflammatory drug delivery., PMID:39501398
Single-Cell Transcriptomics Unveils Skin Cell Specific Antifungal Immune Responses and IL-1Ra- IL-1R Immune Evasion Strategies of Emerging Fungal Pathogen Candida auris., PMID:39463935
Analysis of the role of IL-1 family and related genes in head and neck squamous cell carcinoma., PMID:39461030
Inflammation impacts androgen receptor signaling in basal prostate stem cells through interleukin 1 receptor antagonist., PMID:39455902
Mouse Corneal Immune Cell Heterogeneity Revealed by Single-Cell RNA Sequencing., PMID:39432400
Major depressive disorder, neuroticism, suicidal behaviors, and depression severity are associated with cytokine networks and their intricate interactions with metabolic syndrome., PMID:39413534
Transcriptome Profiling Associated with CARD11 Overexpression in Colorectal Cancer Implicates a Potential Role for Tumor Immune Microenvironment and Cancer Pathways Modulation via NF-κB., PMID:39408697
Fluctuation trend of inflammatory indexes related to gestational diabetes mellitus from second trimester to third trimester of pregnancy., PMID:39395929
Association of circulating cytokine levels and tissue-infiltrating myeloid cells with achalasia: results from Mendelian randomization and validation through clinical characteristics and single-cell RNA sequencing., PMID:39377966
PPARβ/δ Agonist GW0742 Modulates Microglial and Astroglial Gene Expression in a Rat Model of Temporal Lobe Epilepsy., PMID:39337503
Pentylenetetrazole-Induced Seizures Cause Short-Term Changes in the Phenotype of Microglial and Astroglial Cells in the Hippocampus and Temporal Cortex of Young Male Wistar Rats., PMID:39305083
In Situ Analyses of Placental Inflammatory Response to SARS-CoV-2 Infection in Cases of Mother-Fetus Vertical Transmission., PMID:39201511
Influence of IL-β, IL-1RN, and TNF-α variants on the risk of acetylsalicylic acid-induced upper gastrointestinal bleeding: a case-control study., PMID:39194098
Deficiency of interleukin-1 receptor antagonist in mice differentially affects bone properties under different genomic backgrounds., PMID:39191800
Integrated Bioinformatics-Based Identification and Validation of Neuroinflammation-Related Hub Genes in Primary Open-Angle Glaucoma., PMID:39125762
RNAseq of Gingival Fibroblasts Exposed to PRF Membrane Lysates and PRF Serum., PMID:39120336
Characterisation of LPS+ bacterial extracellular vesicles along the gut-hepatic portal vein-liver axis., PMID:39001704
Genetic Markers of Acute Childhood B-Lineage Lymphoblastic Leukemia in the Kazakh Population., PMID:38989811
Binding of interleukin-1 receptor antagonist to cholinergic receptor muscarinic 4 promotes immunosuppression and neuroendocrine differentiation in prostate cancer., PMID:38945201
Comparing machine learning screening approaches using clinical data and cytokine profiles for COVID-19 in resource-limited and resource-abundant settings., PMID:38937503
Exosome microRNA-125a-5p derived from epithelium promotes M1 macrophage polarization by targeting IL1RN in chronic obstructive pulmonary disease., PMID:38875998
Interleukin-1 Receptor Antagonist Gene (IL1RN) Variants Modulate the Cytokine Release Syndrome and Mortality of COVID-19., PMID:38871359
Transcriptional responses consistent with perturbation in dermo-epidermal homeostasis in septic sole ulceration., PMID:38825108
IL27 and IL1RN are causally associated with acute pancreatitis: a Mendelian randomization study., PMID:38742942
Rapid decrease in IL-1Ra and IP-10 plasma levels following tuberculosis treatment initiation., PMID:38740279
Novel anti-inflammatory effects of the IL-1 receptor in kidney myeloid cells following ischemic AKI., PMID:38693918
Case report: Novel compound heterozygous IL1RN mutations as the likely cause of a lethal form of deficiency of interleukin-1 receptor antagonist., PMID:38646532
New discoveries in the genetics and genomics of systemic juvenile idiopathic arthritis., PMID:38641907
Identification and Validation of Novel Metastasis-Related Immune Gene Signature in Breast Cancer., PMID:38634039
For research use only. Not for human or drug use.
