Catalog No.
YHK96501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg90-Pro231
Predicted molecular weight
19.09 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
A2A288
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Probable ribonuclease ZC3H12D, MCP-induced protein 4, Zinc finger CCCH domain-containing protein 12D, TFL, Transformed follicular lymphoma, p34, MCPIP4, ZC3H12D, C6orf95
ZC3H12D gene expression exhibits dual effects on the development and progression of lung adenocarcinoma., PMID:40383849
Synthetic short mRNA prevents metastasis via innate-adaptive immunity., PMID:40000682
ZC3H12D upregulation in head and neck squamous cell carcinoma: a potential prognostic biomarker associated with immune infiltration., PMID:39907408
Comprehensive analysis of the functions, prognostic and diagnostic values of RNA binding proteins in head and neck squamous cell carcinoma., PMID:38844022
The role of ZC3H12D-regulated TLR4-NF-κB pathway in LPS-induced pro-inflammatory microglial activation., PMID:38697601
Tfl deletion induces extraordinary Cxcl13 secretion and cachexia in VavP-Bcl2 transgenic mice., PMID:37304286
Suppression of CEBPδ recovers exhaustion in anti-metastatic immune cells., PMID:36890150
Integrating knowledge of protein sequence with protein function for the prediction and validation of new MALT1 substrates., PMID:36147669
Transcriptome Analysis Reveals the Mechanism of Natural Ovarian Ageing., PMID:35909541
Immune-Related RNA-Binding Protein-Based Signature With Predictive and Prognostic Implications in Patients With Lung Adenocarcinoma., PMID:35647031
Identification of lncRNA Signature of Tumor-Infiltrating T Lymphocytes With Potential Implications for Prognosis and Chemotherapy of Head and Neck Squamous Cell Carcinoma., PMID:35242027
Identification of a ZC3H12D-regulated competing endogenous RNA network for prognosis of lung adenocarcinoma at single-cell level., PMID:35090416
Identification and validation of seven RNA binding protein genes as a prognostic signature in oral cavity squamous cell carcinoma., PMID:34585646
Long non-coding RNA FOXP4-AS1 facilitates the biological functions of hepatocellular carcinoma cells via downregulating ZC3H12D by mediating H3K27me3 through recruitment of EZH2., PMID:34545456
A Novel Prognostic Model for Oral Squamous Cell Carcinoma: The Functions and Prognostic Values of RNA-Binding Proteins., PMID:34395233
Zc3h12d, a Novel of Hypomethylated and Immune-Related for Prognostic Marker of Lung Adenocarcinoma., PMID:34163207
Extracellular mRNA transported to the nucleus exerts translation-independent function., PMID:34135341
Development and validation of a prediction model for lung adenocarcinoma based on RNA-binding protein., PMID:33850871
Identification of Prognosis-related Hub RNA Binding Proteins Function through Regulating Metabolic Processes in Tongue Cancer., PMID:33758601
An optimized workflow for CRISPR-Cas9 deletion of surface and intracellular factors in primary human T lymphocytes., PMID:33600503
A molecular network regulating the proinflammatory phenotype of human memory T lymphocytes., PMID:32205878
ZC3H12B/MCPIP2, a new active member of the ZC3H12 family., PMID:30988100
Intact NYN/PIN-Like Domain is Crucial for the Degradation of Inflammation-Related Transcripts by ZC3H12D., PMID:27472830
[Mediated mechanism of NDRG2 in the regulation of neutrophil nuclear transcription factor-κB signaling pathway through the deubiquitylating enzyme of Zc3h12d]., PMID:26819418
Monocyte Chemotactic Protein-induced Protein 1 and 4 Form a Complex but Act Independently in Regulation of Interleukin-6 mRNA Degradation., PMID:26134560
ZC3H12D attenuated inflammation responses by reducing mRNA stability of proinflammatory genes., PMID:26059755
[Down-regulation of Zc3h12d expression in lung tissues of rats with acute lung injury induced by intestinal ischemia-reperfusion]., PMID:24721400
Posttranscriptional modulation of cytokine production in T cells for the regulation of excessive inflammation by TFL., PMID:24415781
The putative tumor suppressor Zc3h12d modulates toll-like receptor signaling in macrophages., PMID:22036805
p58TFL does not localize to messenger RNA processing bodies., PMID:20068064
Genome-wide survey and expression profiling of CCCH-zinc finger family reveals a functional module in macrophage activation., PMID:18682727
A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages., PMID:18178554
Deregulation of a possible tumour suppressor gene, ZC3H12D, by translocation of IGK@ in transformed follicular lymphoma with t(2;6)(p12;q25)., PMID:17854321
A 212-kb region on chromosome 6q25 containing the TAB2 gene is associated with susceptibility to type 1 diabetes., PMID:15220215
For research use only. Not for human or drug use.
