Catalog No.
YHA43001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp40-Gln178
Predicted molecular weight
18.53 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O15145
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Arp2/3 complex 21 kDa subunit, p21-ARC, ARPC3, Actin-related protein 2/3 complex subunit 3, ARC21
Compound kushen injection inhibits breast cancer lung metastasis through regulating MTSS1/ARPC3/F-actin., PMID:40446975
Liangxue Qushi Zhiyang Decoction Inhibits Atopic Dermatitis in Mice via FcγR-Mediated Phagocytosis., PMID:40322063
Targeted Regulation of HSP70 by the ARP2/3 Complex in Mammary Epithelial Cells and Its Impact on Host Cell Apoptosis., PMID:40305275
Cytochalasin B Mitigates the Inflammatory Response in Lipopolysaccharide-Induced Mastitis by Suppressing Both the ARPC3/ARPC4-Dependent Cytoskeletal Changes and the Association Between HSP70 and the NLRP3 Inflammasome., PMID:40243637
Rare disease gene association discovery in the 100,000 Genomes Project., PMID:40011789
Activation of ARP2/3 and HSP70 Expression by Lipoteichoic Acid: Potential Bidirectional Regulation of Apoptosis in a Mastitis Inflammation Model., PMID:39199289
Design, Synthesis, Characterization, and Cytotoxicity of New Pyrazolylmethylene-2-thioxoimidazolidin-4-one Derivatives towards Androgen-Sensitive LNCaP Prostate Cancer Cells., PMID:39062524
RBCK1 overexpression is associated with immune cell infiltration and poor prognosis in hepatocellular carcinoma., PMID:38214606
Integrative analysis of genes reveals endoplasmic reticulum stress-related immune responses involved in dilated cardiomyopathy with fibrosis., PMID:37462883
Nuclear translocation of cGAS orchestrates VEGF-A-mediated angiogenesis., PMID:37027305
iTRAQ and PRM-Based Comparative Proteomic Profiling of the Hippocampus in Rat Models of Epilepsy., PMID:36722232
A new intracellular targeting motif in the cytoplasmic tail of the spike protein may act as a target to inhibit SARS-CoV-2 assembly., PMID:36572190
CRISPR-Cas9 Arabidopsis mutants of genes for ARPC1 and ARPC3 subunits of ARP2/3 complex reveal differential roles of complex subunits., PMID:36307477
Effects of lipoteichoic and arachidonic acids on the immune-regulatory mechanism of bovine mammary epithelial cells using multi-omics analysis., PMID:36090174
Application of iTRAQ Technology to Identify Differentially Expressed Proteins of Sauce Lamb Tripe with Different Secondary Pasteurization Treatments., PMID:35454754
Expression of actin- and oxidative phosphorylation-related transcripts across the cortical visuospatial working memory network in unaffected comparison and schizophrenia subjects., PMID:35034100
Biallelic truncating variants in ATP9A cause a novel neurodevelopmental disorder involving postnatal microcephaly and failure to thrive., PMID:34379057
Identification of Arp2/3 Complex Subunits as Prognostic Biomarkers for Hepatocellular Carcinoma., PMID:34307456
Identification of Key Genes for Hepatitis Delta Virus-Related Hepatocellular Carcinoma by Bioinformatics Analysis., PMID:33960941
Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction., PMID:33353942
Dysregulation of the Synaptic Cytoskeleton in the PFC Drives Neural Circuit Pathology, Leading to Social Dysfunction., PMID:32726629
Exosomes Derived from the Human Primary Colorectal Cancer Cell Line SW480 Orchestrate Fibroblast-Led Cancer Invasion., PMID:32438511
Mechanistic Target of Rapamycin Regulates the Oligodendrocyte Cytoskeleton during Myelination., PMID:32139584
mir-124-5p Regulates Phagocytosis of Human Macrophages by Targeting the Actin Cytoskeleton via the ARP2/3 Complex., PMID:31636629
The tomato Arp2/3 complex is required for resistance to the powdery mildew fungus Oidium neolycopersici., PMID:31038756
Transgene-associated human growth hormone expression in pancreatic β-cells impairs identification of sex-based gene expression differences., PMID:30532991
Conformational changes in Arp2/3 complex induced by ATP, WASp-VCA, and actin filaments., PMID:30150414
Glycerol monolaurate induces filopodia formation by disrupting the association between LAT and SLP-76 microclusters., PMID:29717064
Frazzled can act through distinct molecular pathways in epithelial cells to regulate motility, apical constriction, and localisation of E-Cadherin., PMID:29518139
TaARPC3, Contributes to Wheat Resistance against the Stripe Rust Fungus., PMID:28769954
The T cell IFT20 interactome reveals new players in immune synapse assembly., PMID:28154159
The role of viral protein Ac34 in nuclear relocation of subunits of the actin-related protein 2/3 complex., PMID:27900558
Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases., PMID:27748747
Identification of reliable reference genes for qRT-PCR studies of the developing mouse mammary gland., PMID:27752147
The Arp2/3 Complex Is Essential for Distinct Stages of Spine Synapse Maturation, Including Synapse Unsilencing., PMID:27629719
Protein Interaction Network of Human Protein Kinase D2 Revealed by Chemical Cross-Linking/Mass Spectrometry., PMID:27559607
Lecithin Prevents Cortical Cytoskeleton Reorganization in Rat Soleus Muscle Fibers under Short-Term Gravitational Disuse., PMID:27073851
A CpG-SNP Located within the ARPC3 Gene Promoter Is Associated with Hypertriglyceridemia in Severely Obese Patients., PMID:27055012
CONTENT OF CYTOSKELETON PROTEINS IN OOCYTES OF THIRD GENERATION DROSOPHILA MELANOGASTER FRUIT FLIES OBTAINED AFTER A 44.5-DAY SPACE FLIGHT., PMID:29873978
SCARN a Novel Class of SCAR Protein That Is Required for Root-Hair Infection during Legume Nodulation., PMID:26517270
Construction of a full-length cDNA library and preliminary analysis of expressed sequence tags from lymphocytes of half-pipe snowboarding athletes., PMID:26505445
Global Gene Expression Profiling in Omental Adipose Tissue of Morbidly Obese Diabetic African Americans., PMID:26504501
Effect of omega-3 polyunsaturated fatty acids on the cytoskeleton: an open-label intervention study., PMID:25971815
The Arp2/3 complex has essential roles in vesicle trafficking and transcytosis in the mammalian small intestine., PMID:25833710
A mechanism of leading-edge protrusion in the absence of Arp2/3 complex., PMID:25568333
Arp2/3 complex regulates adipogenesis by controlling cortical actin remodelling., PMID:25220164
Novel identification of Dermacentor variabilis Arp2/3 complex and its role in rickettsial infection of the arthropod vector., PMID:24733187
Actin-related protein2/3 complex regulates tight junctions and terminal differentiation to promote epidermal barrier formation., PMID:24043783
Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities., PMID:23554489
Nucleation promoting factors regulate the expression and localization of Arp2/3 complex during meiosis of mouse oocytes., PMID:23272233
For research use only. Not for human or drug use.
