Catalog No.
YHK95701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys44-Gln224
Predicted molecular weight
22.57 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q969V5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Mitochondrial-anchored protein ligase, E3 ubiquitin-protein ligase MUL1, Protein Hades, C1orf166, RNF218, Mitochondrial ubiquitin ligase activator of NFKB 1, Growth inhibition and death E3 ligase, MUL1, RING finger protein 218, MAPL, RING-type E3 ubiquitin transferase NFKB 1, Putative NF-kappa-B-activating protein 266, GIDE, MULAN, E3 SUMO-protein ligase MUL1
A DNA tetrahedron-inspired magnetic hybrid with regular distribution of trypsin for ultra-fast digestion of proteins and glycoproteomics analysis., PMID:40476687
Deficiency in the conserved ECHS1 gene causes Leigh syndrome by impairing mitochondrial respiration efficiency and suppressing ADRB2-PKA signaling., PMID:40446940
Effect of haloacetic acid water disinfection byproducts on intestinal barrier function in nematode Caenorhabditis elegans., PMID:40378183
One-Step RAA and CRISPR-Cas13a Method for Detecting Influenza B Virus., PMID:40231967
Electrochemical immunoplatform for the quantification of epithelial extracellular vesicles applied to prostate cancer diagnosis., PMID:40222093
High-efficiency detection of APE1 using a defective PAM-driven CRISPR-Cas12a self-catalytic biosensor., PMID:40157150
TBK1 is a signaling hub in coordinating stress-adaptive mechanisms in head and neck cancer progression., PMID:40114316
Hydrophilic Sulfonate Covalent Organic Frameworks for Serum Glycopeptide Profiling., PMID:40076579
17-beta estradiol prevents cardiac myocyte hypertrophy by regulating mitochondrial E3 ubiquitin ligase 1., PMID:39971924
High-performance affinity peptide sensor for prostate specific antigen detection., PMID:39965325
Construction of a Multiple Cyclic Ligation-Promoted Exponential Recombinase Polymerase Amplification Platform for Sensitive and Simultaneous Monitoring of Cancer Biomarkers Fpg and FEN1., PMID:39880659
Molecular Symphony of Mitophagy: Ubiquitin-Specific Protease-30 as a Maestro for Precision Management of Neurodegenerative Diseases., PMID:39840724
Development of Citric-Acid-Modified Cellulose Monolith for Enriching Glycopeptides., PMID:39772436
Nanoparticle-mediated light-driven LAMP combined with test strips for sensitive and rapid visual detection of antibiotic resistance genes., PMID:39752829
Gold nanocube-enhanced SERS biosensor based on heated electrode coupled with exonuclease III-assisted cycle amplification for sensitive detection of flap endonuclease 1 activity., PMID:39746291
Preparation of a titanium-functionalized polymeric material rich in hydrophilic groups for phosphoproteome and glycoproteome analyses in serum., PMID:39704554
Single and dual RPA-CRISPR/Cas assays for point-of-need detection of Stewart's wilt pathogen (Pantoea stewartii subsp. stewartii) of corn and Maize dwarf mosaic virus., PMID:39663809
Targeting acetylated high mobility group box 1 protein (HMGB1) and toll-like receptor (TLR4) interaction to alleviate hypertension and neuroinflammation in fructose-fed rats., PMID:39627019
A multivariate study on the effect of 3D printing parameters on the printability of gluten-free composite dough., PMID:39610220
[Design and functional validation of a chimeric E3 ubiquitin ligase targeting the spike protein S1 subunit of SARS-CoV-2]., PMID:39584334
Collateral nuclease activity of TnpB triggered by high temperature enables fast and sensitive nucleic acid detection., PMID:39567725
Recombinase polymerase amplification in combination with electrochemical readout for sensitive and specific detection of PIK3CA point mutations., PMID:39492216
Construction of a hydrophilic porphyrin-based MOF@COF hybrid via post-synthetic modification for N-glycopeptides analysis in human serum., PMID:39484847
A gold nanoparticle-enhanced dCas9-mediated fluorescence resonance energy transfer for nucleic acid detection., PMID:39366243
One-Pot Assay for Rapid Detection of Stenotrophomonas maltophilia by RPA-CRISPR/Cas12a., PMID:39358950
Branched hybridization chain reaction and tetrahedral DNA-based trivalent aptamer powered SERS sensor for ultra-highly sensitive detection of cancer-derived exosomes., PMID:39243449
MUL1 identified as mitochondria-linked biomarker promoting cisplatin resistance in OC cells., PMID:39134101
SUMO E3 ligase MUL1 inhibits lymph node metastasis of bladder cancer by mediating mitochondrial HSPA9 translocation., PMID:39113711
Mutation-Selected Amplification droplet digital PCR: A new single nucleotide variant detection assay for TP53R249S mutant in tumor and plasma samples., PMID:39067934
RPA-CRISPR/Cas12a-Mediated Isothermal Amplification for Rapid Detection of Phytopythium helicoides., PMID:39051993
RNA interference-based strategies to control Botrytis cinerea infection in cultivated strawberry., PMID:39048858
Nanoconfined Silver Nanoclusters Combined with X-Shaped DNA Recognizer-Triggered Cascade Amplification for Electrochemiluminescence Detection of APE1., PMID:38946419
HIF-2α expression and metabolic signaling require ACSS2 in clear cell renal cell carcinoma., PMID:38941296
Aptamer based hybrid monolithic pipette tips supported by melamine sponge for enrichment of proteins., PMID:38834272
Electrically Oriented Antibodies on Transistor for Monitoring Several Copies of Methylated DNA., PMID:38747393
Inactivation of mitochondrial MUL1 E3 ubiquitin ligase deregulates mitophagy and prevents diet-induced obesity in mice., PMID:38725872
Increased ROS levels in mitochondrial outer membrane protein Mul1-deficient oocytes result in abnormal preimplantation embryogenesis., PMID:38639871
Effect of humic acid on visible light photocatalytic inactivation of bacteriophage f2 with electrospinning Cu-TiO2 nanofibers: insight into the mechanisms., PMID:38602633
A triggered DNA nanomachine with enzyme-free for the rapid detection of telomerase activity in a one-step method., PMID:38499416
High-Fidelity Sensitive Tracing Circulating Tumor Cell Telomerase Activity., PMID:38483815
NME3 is a gatekeeper for DRP1-dependent mitophagy in hypoxia., PMID:38480688
Fast and sensitive CRISPR detection by minimized interference of target amplification., PMID:38332130
Resistance to both aphids and nematodes in tobacco plants expressing a Bacillus thuringiensis crystal protein., PMID:38319036
Enhancing spinal cord stimulation-induced pain inhibition by augmenting endogenous adenosine signalling after nerve injury in rats., PMID:38310069
Dupilumab sustains lung function improvements in patients with moderate-to-severe asthma., PMID:38272376
Facile preparation of nitrogen/titanium-rich porous organic polymers for specific enrichment of N-glycopeptides and phosphopeptides., PMID:38214200
Multiply-mesoporous hydrophilic titanium dioxide nanohybrid for the highly-performed enrichment of N-glycopeptides from human serum., PMID:38182336
Mitophagy Decreases in the Peripheral Vestibular System of Aged C57BL/6J Mice., PMID:38148055
Amide and Multihydroxyl Complementary Tailored Metal-Organic Framework with Enhanced Glycan Affinity for Efficient Glycoproteomic Analysis., PMID:38145926
Role of the Mitochondrial E3 Ubiquitin Ligases as Possible Therapeutic Targets in Cancer Therapy., PMID:38139010
For research use only. Not for human or drug use.
