Catalog No.
YHA25303
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser413-Ser511
Predicted molecular weight
23.67 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O14640
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DVL1, DSH homolog 1, Dishevelled-1, Segment polarity protein dishevelled homolog DVL-1
Sp2 Transcription Factor Alleviates Chondrocyte Loss in Osteoarthritis by Repressing the DVL1-Dependent Wnt/β-Catenin Signaling Pathway., PMID:40420355
WNT Signaling Factors as Potential Synovial Inflammation Moderators in Patients with Hip Osteoarthritis., PMID:40299569
Human neuron chimeric mice reveal impairment of DVL-1-mediated neuronal migration by sevoflurane and potential treatment by rTMS., PMID:40164685
PAR2 Serves an Indispensable Role in Controlling PAR4 Oncogenicity: The β-Catenin-p53 Axis., PMID:40141421
Complex G-protein signaling of the adhesion GPCR, ADGRA3., PMID:40127866
Dact1 induces Dishevelled oligomerization to facilitate binding partner switch and signalosome formation during convergent extension., PMID:40069199
Increased activation of the WNT pathway in brain tissue from patients with cortical dysplasia type IIb., PMID:40055364
Spatiotemporal distribution of Wnt signaling pathway markers in human congenital anomalies of kidney and urinary tract., PMID:39908631
Evaluation of LRP6, SFRP3, and DVL1 Protein Concentrations in Serum of Patients with Gastroenteropancreatic or Bronchopulmonary Neuroendocrine Tumors., PMID:39796676
Expression of Wnt signaling proteins LEF1, β-catenin, GSK3β, DVL1, and N-myc varies across retinoblastoma subtypes and pRb phosphorylation status., PMID:39738380
Exploration and identification of diabetes targets in nursing: CDH1 and DVL1., PMID:39495995
Exploring DIX-DIX Homo- and Hetero-Oligomers in Wnt Signaling with AlphaFold2., PMID:39404409
The LncRNA6524/miR-92a-2-5p/Dvl1/Wnt/β-catenin axis promotes renal fibrosis in the UUO mouse model., PMID:39389150
Analyzing the role of TM4SF1 expression in pancreatic adenocarcinoma: understanding prognostic implications and therapeutic opportunities., PMID:39279979
Copy number variation and clinical response to chemotherapy and bevacizumab in the Czech metastatic colorectal cancer patients., PMID:39174331
The Role of NOTCH Pathway Genes in the Inherited Susceptibility to Aortic Stenosis., PMID:39057646
Fetal phenotype and diagnosis of autosomal dominant Robinow syndrome due to novel DVL1 variant., PMID:38982229
Human Genetics of Ventricular Septal Defect., PMID:38884729
A vertebrate Vangl2 translational variant required for planar cell polarity., PMID:38403249
Transient suppression of Wnt signaling in poor-quality buffalo oocytes improves their developmental competence., PMID:38274663
HECW1 restrains cervical cancer cell growth by promoting DVL1 ubiquitination and downregulating the activation of Wnt/β-catenin signaling., PMID:38266865
Stem-cell-expressed DEVIL-like small peptides maintain root growth under abiotic stress via abscisic acid signaling., PMID:38096479
RNA helicase DDX5 modulates sorafenib sensitivity in hepatocellular carcinoma via the Wnt/β-catenin-ferroptosis axis., PMID:38036507
HIV gp120/Tat protein-induced epithelial-mesenchymal transition promotes the progression of cervical lesions., PMID:37981694
Shade-induced RTFL/DVL peptides negatively regulate the shade response by directly interacting with BSKs in Arabidopsis., PMID:37898648
Disheveled-1 Interacts with Claudin-5 and Contributes to Norrin-Induced Endothelial Barrier Restoration., PMID:37830616
Proanthocyanidins inhibited colorectal cancer stem cell characteristics through Wnt/β-catenin signaling., PMID:37551626
A Van Gogh/Vangl tyrosine phosphorylation switch regulates its interaction with core Planar Cell Polarity factors Prickle and Dishevelled., PMID:37463168
Dishevelled segment polarity protein 2 promotes gastric cancer progression through Wnt/β-catenin pathway., PMID:37257286
Disturbances in Switching between Canonical and Non-Canonical Wnt Signaling Characterize Developing and Postnatal Kidneys of Dab1-/- (yotari) Mice., PMID:37238991
Effect of DNA aptamer through blocking of negative regulation of Wnt/β-catenin signaling in human hair follicle dermal papilla cells., PMID:37231925
The Wnt pathway protein Dvl1 targets somatostatin receptor 2 for lysosome-dependent degradation., PMID:36965619
circMMD reduction following tumor treating fields inhibits glioblastoma progression through FUBP1/FIR/DVL1 and miR-15b-5p/FZD6 signaling., PMID:36932454
Mechanistic studies in Drosophila and chicken give new insights into functions of DVL1 in dominant Robinow syndrome., PMID:36916233
SPATA2 suppresses epithelial-mesenchymal transition to inhibit metastasis and radiotherapy sensitivity in non-small cell lung cancer via impairing DVL1/β-catenin signaling., PMID:36814090
Dishevelled 2 regulates cancer cell proliferation and T cell mediated immunity in HER2-positive breast cancer., PMID:36809986
Hyperoxia exposure upregulates Dvl-1 and activates Wnt/β-catenin signaling pathway in newborn rat lung., PMID:36726071
The non-invasive diagnosis of colorectal cancer via a SOX9-based gene panel., PMID:36637582
Dvl proteins regulate SMAD1, AHR, mTOR, BRD7 protein expression while differentially regulating canonical and non-canonical Wnt signaling pathways in CML cell lines., PMID:36509295
Human Placenta-Derived Mesenchymal Stem Cells Ameliorate Diabetic Neuropathy via Wnt Signaling Pathway., PMID:36440182
Transcriptome Sequencing Analysis of circRNA in Skeletal Muscle between Fast- and Slow-Growing Chickens at Embryonic Stages., PMID:36428392
PLAGL2 increases adriamycin resistance and EMT in breast cancer cells by activating the Wnt pathway., PMID:36399309
[Inhibition of the Wnt signaling pathway contributes to the cardiac protection of exercise training in spontaneously hypertensive rats]., PMID:36319100
Effect of triadimefon on rat placental morphology, function, and gene expression., PMID:36179991
Identification and Validation of Prognostic Markers for Lung Squamous Cell Carcinoma Associated with Chronic Obstructive Pulmonary Disease., PMID:36035311
Loureirin B downregulates osteoclast differentiation of bone marrow macrophages by targeting the MAPK signaling pathway., PMID:35999378
DKK3 ameliorates neuropathic pain via inhibiting ASK-1/JNK/p-38-mediated microglia polarization and neuroinflammation., PMID:35658977
DVL1 and DVL3 require nuclear localisation to regulate proliferation in human myoblasts., PMID:35589804
Anticonvulsive and Neuroprotective Effects of Eupafolin in Rats Are Associated with the Inhibition of Glutamate Overexcitation and Upregulation of the Wnt/β-Catenin Signaling Pathway., PMID:35500294
PITX2 regulates steroidogenesis in granulosa cells of dairy goat by the WNT/β-catenin pathway., PMID:35300988
For research use only. Not for human or drug use.
