Catalog No.
YHJ98802
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln870-Ala1016
Predicted molecular weight
27.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y6C2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Elastin microfibril interface-located protein 1, EMI, Elastin microfibril interfacer 1, EMILIN-1, EMILIN1
Generation of a genome-edited EMILIN1 (c.1606C>T) hiPSC line to investigate aortic aneurysm formation in vitro., PMID:40222083
Embryonic reprogramming of the tumor vasculature reveals targets for cancer therapy., PMID:40096611
Novel De Novo BRCA2 Variant in an Early-Onset Ovarian Cancer Reveals a Unique Tumor Evolution Pathway., PMID:40076915
EMILIN-1 Suppresses Cell Proliferation through Altered Cell Cycle Regulation in Head and Neck Squamous Cell Carcinoma., PMID:39892781
Sexual dimorphism in the downregulation of extracellular matrix genes contributes to aortic stiffness in female mice., PMID:39873616
Zonulopathies as Genetic Disorders of the Extracellular Matrix., PMID:39766898
Extravillous trophoblasts reverse the decidualization induced increase in matrix production by secreting TGFβ antagonists Emilin-1 and Gremlin-1., PMID:39756583
New insights into the structural role of EMILINs within the human skin microenvironment., PMID:39639116
Fe3O4 nanoparticles containing gambogic acid inhibit metastasis in colorectal cancer via the RORB/EMILIN1 axis., PMID:39533963
α9β1 integrin & its ligands as new potential biomarkers in FMF., PMID:39382510
EMILIN1 gene variant associated with polyneuropathy, language impairment, and motor dysfunction., PMID:38963291
The extracellular matrix protein EMILIN-1 impacts on the microenvironment by hampering gastric cancer development and progression., PMID:38941035
Generation of Tailored Extracellular Matrix Hydrogels for the Study of In Vitro Folliculogenesis in Response to Matrisome-Dependent Biochemical Cues., PMID:38927779
Emilin2 marks the target region for mesenchymal cell accumulation in bone regeneration., PMID:38831448
Downregulation of MYBL1 in endothelial cells contributes to atherosclerosis by repressing PLEKHM1-inducing autophagy., PMID:38797732
Cancer-associated fibroblast spatial heterogeneity and EMILIN1 expression in the tumor microenvironment modulate TGF-β activity and CD8+ T-cell infiltration in breast cancer., PMID:38505604
Integrated machine learning-driven disulfidptosis profiling: CYFIP1 and EMILIN1 as therapeutic nodes in neuroblastoma., PMID:38427078
Elastin microfibril interface-located protein 1 in fibroblasts is regulated by amphiregulin and interleukin-1α produced by keratinocytes., PMID:38356201
Effects of laparoscopic sleeve gastrectomy on nonalcoholic fatty liver disease and TGF-β signaling pathway., PMID:38171883
Assessment of α9β1 ıntegrın as a new dıagnostıc and therapeutıc target ın Behcet's dısease., PMID:37728818
The Genetic Association with Athlete Status, Physical Performance, and Injury Risk in Soccer., PMID:37253386
The role of EMILIN-1 in the osteo/odontogenic differentiation of dental pulp stem cells., PMID:37024847
Prediction of transcript structure and concentration using RNA-Seq data., PMID:36682028
Computer-Aided Imaging Analysis of Probe-Based Confocal Laser Endomicroscopy With Molecular Labeling and Gene Expression Identifies Markers of Response to Biological Therapy in IBD Patients: The Endo-Omics Study., PMID:36378498
EMILIN1 deficiency causes arterial tortuosity with osteopenia and connects impaired elastogenesis with defective collagen fibrillogenesis., PMID:36351433
FOXD1 is required for 3D patterning of the kidney interstitial matrix., PMID:36335435
EMILIN-1 deficiency promotes chronic inflammatory disease through TGFβ signaling alteration and impairment of the gC1q/α4β1 integrin interaction., PMID:35764213
miR-491-5p inhibits Emilin 1 to promote fibroblasts proliferation and fibrosis in gluteal muscle contracture via TGF-Beta1/Smad2 pathway., PMID:35275699
Human amniotic epithelial cell transplantation improves scar remodeling in a rabbit model of acute vocal fold injury: a pilot study., PMID:35073957
ANTXR1 as a potential prognostic biomarker for hepatitis B virus-related hepatocellular carcinoma identified by a weighted gene correlation network analysis., PMID:35070431
Elastin microfibril interface-located protein 1 and its catabolic enzyme, cathepsin K, regulate the age-related structure of elastic fibers in the skin., PMID:35064622
Phenotyping Zebrafish Mutant Models to Assess Candidate Genes Associated with Aortic Aneurysm., PMID:35052463
Increased Desmosine in the lens capsules is associated with augmented elastin turnover in Pseudoexfoliation syndrome., PMID:34929161
Elastin MIcrofibriL INterfacer1 (EMILIN-1) is an alternative prosurvival VLA-4 ligand in chronic lymphocytic leukemia., PMID:34783040
The genetic association with injury risk in male academy soccer players depends on maturity status., PMID:34633711
Inactivation of EMILIN-1 by Proteolysis and Secretion in Small Extracellular Vesicles Favors Melanoma Progression and Metastasis., PMID:34299025
Proteomic Changes during the Dermal Toxicity Induced by Nemopilema nomurai Jellyfish Venom in HaCaT Human Keratinocyte., PMID:33925349
Complexity of matrix phenotypes., PMID:33543032
EMILIN proteins are novel extracellular constituents of the dentin-pulp complex., PMID:32948785
Spatiotemporal changes in mechanical matrisome components of the human ovary from prepuberty to menopause., PMID:32539154
Extracellular Matrix Analysis of Human Renal Arteries in Both Quiescent and Active Vascular State., PMID:32486169
A homozygous missense variant in CACNB4 encoding the auxiliary calcium channel beta4 subunit causes a severe neurodevelopmental disorder and impairs channel and non-channel functions., PMID:32176688
Distal motor neuropathy associated with novel EMILIN1 mutation., PMID:31978608
The plasma peptides of breast versus ovarian cancer., PMID:31889940
Molecular recognition of aortic valve stenosis and regurgitation., PMID:31858570
Prechondrogenic ATDC5 Cell Attachment and Differentiation on Graphene Foam; Modulation by Surface Functionalization with Fibronectin., PMID:31639302
Gene Expression Profiling of the Extracellular Matrix Signature in Macrophages of Different Activation Status: Relevance for Skin Wound Healing., PMID:31615030
Abrogation of EMILIN1-β1 integrin interaction promotes experimental colitis and colon carcinogenesis., PMID:31479698
A proteome comparison between human fetal and mature renal extracellular matrix identifies EMILIN1 as a regulator of renal epithelial cell adhesion., PMID:33543009
Molecular prognosticators in clinically and pathologically distinct cohorts of head and neck squamous cell carcinoma-A meta-analysis approach., PMID:31310629