Catalog No.
YHK94301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Arg179
Predicted molecular weight
22.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96KC2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ADP-ribosylation factor-like protein 5B, ADP-ribosylation factor-like protein 8, ARL5B, ARL8
Synaptic Vesicle Glycoprotein 2A Slows down Amyloidogenic Processing of Amyloid Precursor Protein via Regulating Its Intracellular Trafficking., PMID:40506382
Construction of AML prognostic model with CYP2E1 and GALNT12 biomarkers based on golgi- associated genes., PMID:39604595
Human rhinovirus 16 induces an ICAM-1-PKR-ATF2 axis to modulate macrophage functions., PMID:39324790
[HRV16 inhibits bacterial clearance in a ARL5b-dependent manner]., PMID:38986089
Circ-N4BP2L2 enhances mitochondrial function in non-small cell lung cancer cells through regulating the miR-135a-5p/ARL5B axis., PMID:36637163
Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB., PMID:35844135
Interacting partners of Golgi-localized small G protein Arl5b identified by a combination of in vivo proximity labelling and GFP-Trap pull down., PMID:35789482
Knockdown of ARL5B Induces Mitochondrial-mediated Apoptosis and Inhibits Glycolysis in Breast Cancer Cells by Activating MDA5 Signaling., PMID:35546774
Binding with heat shock cognate protein HSC70 fine-tunes the Golgi association of the small GTPase ARL5B., PMID:34798070
miR-145 inhibits mitochondrial function of ovarian cancer by targeting ARL5B., PMID:33419459
ARL8 Relieves SKIP Autoinhibition to Enable Coupling of Lysosomes to Kinesin-1., PMID:33232665
A Multiancestry Sex-Stratified Genome-Wide Association Study of Spontaneous Clearance of Hepatitis C Virus., PMID:33119750
The FTO/miR-181b-3p/ARL5B signaling pathway regulates cell migration and invasion in breast cancer., PMID:32805088
Advanced glycation end products reduce macrophage-mediated killing of Staphylococcus aureus by ARL8 upregulation and inhibition of autolysosome formation., PMID:32250445
Neuronal Soma-Derived Degradative Lysosomes Are Continuously Delivered to Distal Axons to Maintain Local Degradation Capacity., PMID:31269450
The trans-Golgi network is a major site for α-secretase processing of amyloid precursor protein in primary neurons., PMID:30545942
Profiling the MAPK/ERK dependent and independent activity regulated transcriptional programs in the murine hippocampus in vivo., PMID:28349920
Amyloid precursor protein traffics from the Golgi directly to early endosomes in an Arl5b- and AP4-dependent pathway., PMID:28000370
Human Cytotoxic T Lymphocytes Form Dysfunctional Immune Synapses with B Cells Characterized by Non-Polarized Lytic Granule Release., PMID:27052167
BORC, a multisubunit complex that regulates lysosome positioning., PMID:25898167
The small G protein Arl5 contributes to endosome-to-Golgi traffic by aiding the recruitment of the GARP complex to the Golgi., PMID:25795912
Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B., PMID:25451939
Integrated pathway-based approach identifies association between genomic regions at CTCF and CACNB2 and schizophrenia., PMID:24901509
Arl5b is a Golgi-localised small G protein involved in the regulation of retrograde transport., PMID:22245584
Arl8 and SKIP act together to link lysosomes to kinesin-1., PMID:22172677
Interconversion of two GDP-bound conformations and their selection in an Arf-family small G protein., PMID:21742265
Genome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study., PMID:20932310
An Arf-like small G protein, ARL-8, promotes the axonal transport of presynaptic cargoes by suppressing vesicle aggregation., PMID:20547129
The epithelial membrane protein 1 is a novel tight junction protein of the blood-brain barrier., PMID:18382472
The involvement of arl-5b in the repair of hair cells in sea anemones., PMID:17332968
Isolation of a new member of the ADP-ribosylation like factor gene family, ARL8, from a cartilage cDNA library., PMID:12853149
For research use only. Not for human or drug use.
