Catalog No.
YHH01301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala1325-Gly1411
Predicted molecular weight
23.27 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15075
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EEA1, Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2, ZFYVE2, Early endosome antigen 1
CD44-targeted RIP3 gene delivery strategy for enhanced cancer therapy via necroptosis and immune modulation., PMID:40436345
Synthesis, Molecular Docking, and Biological Activity of New EGFR-Targeted Photosensitizers Based on Cationic Porphyrins Encapsulated into Pluronic F127 Micelles., PMID:40340474
RNF13 variants L311S and L312P associated with developmental epileptic encephalopathy alter dendritic organization in hippocampal neurons., PMID:40276023
CD36-mediated endocytosis of proteolysis-targeting chimeras., PMID:40250420
Dual roles of CXCR4 (C-X-C motif chemokine receptor 4) in promoting entry of ebolavirus and targeting excessive glycoprotein for reticulophagic degradation to facilitate viral fitness., PMID:40223186
Eeukaryotic-like Sppsk1 from Vibrio splendidus AJ01 mediates phagosome escape via inhibiting phagosome acidification and maturation., PMID:39985586
PI3KC2β depletion rescues endosomal trafficking defects in Mtm1 knockout skeletal muscle cells., PMID:39952567
Icariin improves learning and memory function by enhancing HRD1-mediated ubiquitination of amyloid precursor protein in APP/PS1 mice., PMID:39814545
Magnetic control of membrane damage in early endosomes using internalized magnetic nanoparticles., PMID:39756866
Motor Function of the Two-Component EEA1-Rab5 Revealed by dcFCCS., PMID:39704939
Interleukin-4 promotes the clearance of amyloid-β by monocyte through enhancing the recognition and intracellular processing of amyloid-β., PMID:39660534
Endo-IP and lyso-IP toolkit for endolysosomal profiling of human-induced neurons., PMID:39636867
Prolactin-specific induction of the nuclear translocation of porcine prolactin receptor in porcine mammary epithelial cells., PMID:39561513
Human Coronavirus 229E Uses Clathrin-Mediated Endocytosis as a Route of Entry in Huh-7 Cells., PMID:39456165
Endo-IP and Lyso-IP Toolkit for Endolysosomal Profiling of Human Induced Neurons., PMID:39386502
Impaired endocytosis and accumulation in early endosomal compartments defines herpes simplex virus-mediated disruption of the nonclassical MHC class I-related molecule MR1., PMID:39260697
Serotonin Influences Insulin Secretion in Rat Insulinoma INS-1E Cells., PMID:38999937
Xiaowugui decoction alleviates experimental rheumatoid arthritis by suppressing Rab5a-mediated TLR4 internalization in macrophages., PMID:38964156
Comprehensive knockout analysis of the RAB family small GTPases reveals an overlapping role of RAB2 and RAB14 in autophagosome maturation., PMID:38953305
3D Computational Modeling of Defective Early Endosome Distribution in Human iPSC-Based Cardiomyopathy Models., PMID:38891055
The different roles of V-ATPase a subunits in phagocytosis/endocytosis and autophagy., PMID:38873931
Circadian Regulation of Leishmania Parasite Internalisation in Macrophages and Downstream Cellular Events., PMID:38817112
Pathogenic and Apathogenic Strains of Lymphocytic Choriomeningitis Virus Have Distinct Entry and Innate Immune Activation Pathways., PMID:38675975
Septin-coated microtubules promote maturation of multivesicular bodies by inhibiting their motility., PMID:38668767
Spatiotemporal proteomic profiling of cellular responses to NLRP3 agonists., PMID:38659763
Flotillins affect LPS-induced TLR4 signaling by modulating the trafficking and abundance of CD14., PMID:38652315
The colonization factor CS6 of enterotoxigenic Escherichia coli contributes to host cell invasion., PMID:38556103
Intraluminal vesicle trafficking is involved in the secretion of base excision repair protein APE1., PMID:38401056
Human Adenovirus Entry and Early Events during Infection of Primary Murine Neurons: Immunofluorescence Studies In Vitro., PMID:38392896
Endosomal protein expression of γ1-adaptin is associated with tumor growth activity and relapse-free survival in breast cancer., PMID:38265632
Loss of the HOPS complex disrupts early-to-late endosome transition, impairs endosomal recycling and induces accumulation of amphisomes., PMID:38198575
Roles of epidermal growth factor receptor, claudin-1 and occludin in multi-step entry of hepatitis C virus into polarized hepatoma spheroids., PMID:38157366
Basal interaction of the orphan receptor GPR101 with arrestins leads to constitutive internalization., PMID:38151077
A genome-wide CRISPR/Cas9 screen identifies a role for Rab5A and early endosomes in hepatitis E virus replication., PMID:38109552
Protocol for determination of phosphatidylinositol 3-phosphate levels and localization in Candida glabrata by confocal microscopy., PMID:38088931
Galectin-3 Mediates Endotoxin Internalization and Caspase-4/11 Activation in Tubular Epithelials and Macrophages During Sepsis and Sepsis-Associated Acute Kidney Injury., PMID:37979076
NDP52 SUMOylation contributes to low-dose X-rays-induced cardiac hypertrophy through PINK1/Parkin-mediated mitophagy via MUL1/SUMO2 signalling., PMID:37942585
Removal of hypersignaling endosomes by simaphagy., PMID:37840274
Hepatitis B virus promotes its own replication by enhancing RAB5A-mediated dual activation of endosomal and autophagic vesicle pathways., PMID:37725090
Phosphorylation-state dependent intraneuronal sorting of Aβ differentially impairs autophagy and the endo-lysosomal system., PMID:37642583
Deterministic early endosomal maturations emerge from a stochastic trigger-and-convert mechanism., PMID:37532690
Budding uninhibited by benzimidazoles-1 (BUB1) regulates EGFR signaling by reducing EGFR internalization., PMID:37399454
Adenosine A2A Receptor Activation Regulates Niemann-Pick C1 Expression and Localization in Macrophages., PMID:37367064
Phafins Are More Than Phosphoinositide-Binding Proteins., PMID:37175801
Contribution of vesicle trafficking dysregulation to the pathomechanism of mucopolysaccharidosis., PMID:37149983
SORL1 stabilizes ABCB1 to promote cisplatin resistance in ovarian cancer., PMID:37145301
The phosphatidylinositol 3-phosphate effector FYVE3 regulates FYVE2-dependent autophagy in Arabidopsis thaliana., PMID:37008475
Intestinal Barrier in Post-Campylobacter jejuni Irritable Bowel Syndrome., PMID:36979384
Porcine Enteric Alphacoronavirus Entry through Multiple Pathways (Caveolae, Clathrin, and Macropinocytosis) Requires Rab GTPases for Endosomal Transport., PMID:36975780
Exploring the common pathogenesis of Alzheimer's disease and type 2 diabetes mellitus via microarray data analysis., PMID:36923118
For research use only. Not for human or drug use.
