Catalog No.
YHF45401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Phe193
Predicted molecular weight
24.41 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P61601
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NCALD, Neurocalcin-delta
miR-182-5p facilitates colorectal cancer progression through manipulating neurocalcin delta mediated Wnt/β-catenin signalling., PMID:40312722
Gene expression regulation and polyadenylation in ulcerative colitis via long-chain RNA sequencing., PMID:39955510
Construction of AML prognostic model with CYP2E1 and GALNT12 biomarkers based on golgi- associated genes., PMID:39604595
Long non-coding RNA MIDEAS-AS1 inhibits growth and metastasis of triple-negative breast cancer via transcriptionally activating NCALD., PMID:37770991
A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores., PMID:37349795
A genome-wide association analysis of loss of ambulation in dystrophinopathy patients suggests multiple candidate modifiers of disease severity., PMID:36935420
Long-Term SMN- and Ncald-ASO Combinatorial Therapy in SMA Mice and NCALD-ASO Treatment in hiPSC-Derived Motor Neurons Show Protective Effects., PMID:36835624
NCALD as a potential predictive biomarker for the efficacy of platinum-based chemotherapy in ovarian cancer., PMID:36444691
Zinc Modulation of Neuronal Calcium Sensor Proteins: Three Modes of Interaction with Different Structural Outcomes., PMID:35883512
Genome-Wide Association Study of Egg-Laying Traits and Egg Quality in LingKun Chickens., PMID:35795788
N6‑methyladenosine upregulates miR‑181d‑5p in exosomes derived from cancer‑associated fibroblasts to inhibit 5‑FU sensitivity by targeting NCALD in colorectal cancer., PMID:35014676
Helicid Reverses the Effect of Overexpressing NCALD, Which Blocks the sGC/cGMP/PKG Signaling Pathway in the CUMS-Induced Rat Model., PMID:34931140
Identification of potential genes in upper tract urothelial carcinoma using next-generation sequencing with bioinformatics and in vitro analyses., PMID:33987019
Antidepressant-like effects of helicid on a chronic unpredictable mild stress-induced depression rat model: Inhibiting the IKK/IκBα/NF-κB pathway through NCALD to reduce inflammation., PMID:33578182
Calcium-Dependent Translocation of S100B Is Facilitated by Neurocalcin Delta., PMID:33466232
The role of circadian rhythm in the regulation of cellular protein profiles in the brain., PMID:33356029
Identification of key genes in lung adenocarcinoma based on a competing endogenous RNA network., PMID:33281971
A Novel Approach to Bacterial Expression and Purification of Myristoylated Forms of Neuronal Calcium Sensor Proteins., PMID:32664359
Low expression of NCALD is associated with chemotherapy resistance and poor prognosis in epithelial ovarian cancer., PMID:32228639
NCALD affects drug resistance and prognosis by acting as a ceRNA of CX3CL1 in ovarian cancer., PMID:32030795
NCALD Antisense Oligonucleotide Therapy in Addition to Nusinersen further Ameliorates Spinal Muscular Atrophy in Mice., PMID:31230718
Clinicopathological and prognostic significance of NCALD protein expression in lung adenocarcinoma., PMID:35116813
High NCALD expression predicts poor prognosis of cytogenetic normal acute myeloid leukemia., PMID:31109331
Neurocalcin Delta Knockout Impairs Adult Neurogenesis Whereas Half Reduction Is Not Pathological., PMID:30853885
Characterization of neurocalcin delta membrane binding by biophysical methods., PMID:30469050
Investigating the possible causal association of coffee consumption with osteoarthritis risk using a Mendelian randomization analysis., PMID:30076541
CHP1 reduction ameliorates spinal muscular atrophy pathology by restoring calcineurin activity and endocytosis., PMID:29961886
Neurocalcin-delta: a potential memory-related factor in hippocampus of obese rats induced by high-fat diet., PMID:29937895
Advances in understanding the role of disease-associated proteins in spinal muscular atrophy., PMID:28635376
Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis., PMID:28132687
Data on the calcium-induced mobility shift of myristoylated and non-myristoylated forms of neurocalcin delta., PMID:27054169
Upregulation of long intergenic noncoding RNA 00673 promotes tumor proliferation via LSD1 interaction and repression of NCALD in non-small-cell lung cancer., PMID:27027352
Characterizing the molecular features of ERG-positive tumors in primary and castration resistant prostate cancer., PMID:26990456
Proteome-wide Identification of Novel Ceramide-binding Proteins by Yeast Surface cDNA Display and Deep Sequencing., PMID:26729710
Interaction between Common Genetic Variants and Total Fat Intake on Low-Density Lipoprotein Peak Particle Diameter: A Genome-Wide Association Study., PMID:26112879
The EHEC-host interactome reveals novel targets for the translocated intimin receptor., PMID:25519916
Inactivation of the paraoxonase 1 gene affects the expression of mouse brain proteins involved in neurodegeneration., PMID:24844689
Refinement of the deletion in 8q22.2-q22.3: the minimum deletion size at 8q22.3 related to intellectual disability and epilepsy., PMID:24801133
Hyperhomocysteinemia and bleomycin hydrolase modulate the expression of mouse brain proteins involved in neurodegeneration., PMID:24496069
Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1., PMID:24387768
[Genetic study for diabetic microvascular complications--recent advances and future perspectives]., PMID:23156397
Integrative approach to pain genetics identifies pain sensitivity loci across diseases., PMID:22685391
Promoter regulation of the visinin-like subfamily of neuronal calcium sensor proteins by nuclear respiratory factor-1., PMID:19674972
Rod outer segment membrane guanylate cyclase type 1 (ROS-GC1) calcium-modulated transduction system in the sperm., PMID:19111294
Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy., PMID:17671797
Identification of Ca2+-dependent binding partners for the neuronal calcium sensor protein neurocalcin delta: interaction with actin, clathrin and tubulin., PMID:11964161
Molecular cloning, mapping and characterization of the human neurocalcin delta gene (NCALD)., PMID:11267673
Neurocalcin family: a novel calcium-binding protein abundant in bovine central nervous system., PMID:8387172
For research use only. Not for human or drug use.
