Catalog No.
YHD97302
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly10-Asp196
Predicted molecular weight
23.57 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P31943
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HNRPH1, hnRNP H, HNRNPH1, HNRPH, Heterogeneous nuclear ribonucleoprotein H
hnRNPH1: A Multifaceted Regulator in RNA Processing and Disease Pathogenesis., PMID:40507967
The striatal heterogeneous nuclear ribonucleoprotein H mRNA targetome associated with methamphetamine administration and behavior., PMID:40502192
HNRNPH1 promotes autophagy to inhibit the development of lung adenocarcinoma via the HSP90AB1/MAP1LC3B axis., PMID:40468317
The AhR regulates IFN-induced immune checkpoints in lung cancer cells through HNRNPH1, an RNA-binding protein, and INCR1, a novel long non-coding RNA., PMID:40449595
The adult HNRNPH1::ERG positive acute myeloid leukemia with clear lower remission and worse prognosis: A case report and review of the literature., PMID:40193682
[The splicing factor HNRNPH1 regulates Circ-MYOCD back-splicing to modulate the course of cardiac hypertrophy]., PMID:40159973
PTK6 drives HNRNPH1 phase separation to activate autophagy and suppress apoptosis in colorectal cancer., PMID:40103198
Eukaryotic RNA binding protein hnRNPH1 suppresses influenza A virus replication through interaction with virus NS1 protein., PMID:40052960
hnRNPH1 Inhibits Influenza Virus Replication by Binding Viral RNA., PMID:39858792
Japanese encephalitis virus NS3 captures the protein translation element by interacting with HNRNPH1 to promote viral replication., PMID:39694377
Alternative Splicing: A Potential Therapeutic Target in Hematological Malignancies., PMID:39584923
HNRNPH1 stabilizes FLOT2 mRNA in a non-canonical m6A-dependent manner to promote malignant progression in nasopharyngeal carcinoma., PMID:39570559
BCAS2 and hnRNPH1 orchestrate alternative splicing for DNA double-strand break repair and synapsis in meiotic prophase I., PMID:39520542
On the interface of aging, cancer, and neurodegeneration with SIRT6 and L1 retrotransposon protein interaction network., PMID:39251041
MACC1 enhances an oncogenic RNA splicing of IRAK1 through interacting with HNRNPH1 in lung adenocarcinoma., PMID:39221900
Viral hijacking of hnRNPH1 unveils a G-quadruplex-driven mechanism of stress control., PMID:39094585
Identification of hub genes and potential molecular mechanisms in MSS/MSI classifier primary colorectal cancer based on multiple datasets., PMID:39023715
hnRNPH1 maintains mitochondrial homeostasis by establishing NRF1/DRP1 retrograde signaling under mitochondrial stress., PMID:38898233
SARS-CoV-2 Selectively Induces the Expression of Unproductive Splicing Isoforms of Interferon, Class I MHC, and Splicing Machinery Genes., PMID:38891862
Biological relevance of alternative splicing in hematologic malignancies., PMID:38760666
METTL3-Mediated LINC00475 Alternative Splicing Promotes Glioma Progression by Inducing Mitochondrial Fission., PMID:38405130
Phosphoproteome analysis of the crosstalk between sumoylation and phosphorylation in mouse spermatocytes., PMID:37783117
Novel Anti-Melanoma Compounds Are Efficacious in A375 Cell Line Xenograft Melanoma Model in Nude Mice., PMID:37759675
TFRC-RNA interactions show the regulation of gene expression and alternative splicing associated with IgAN in human renal tubule mesangial cells., PMID:37547464
A murine model of hnRNPH2-related neurodevelopmental disorder reveals a mechanism for genetic compensation by Hnrnph1., PMID:37463454
Acute Undifferentiated Leukemia With a Balanced t(5;10)(q35;p12) Resulting in Fusion of HNRNPH1 With MLLT10., PMID:37400142
A new Karyopherin-β2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders., PMID:37279758
HNRNPH1 regulates the neuroprotective cold-shock protein RBM3 expression through poison exon exclusion., PMID:37248947
Transcriptomic and immunophenotypic characterization of two cases of adamantinoma-like Ewing sarcoma of the thyroid gland., PMID:37195579
Identification of bicalutamide resistance-related genes and prognosis prediction in patients with prostate cancer., PMID:37143720
MicroRNA-Based Markers of Oral Tongue Squamous Cell Carcinoma and Buccal Squamous Cell Carcinoma: A Systems Biology Approach., PMID:37143570
The HNRNPF/H RNA binding proteins and disease., PMID:37042074
In Vivo Acute Toxicity Studies of Novel Anti-Melanoma Compounds Downregulators of hnRNPH1/H2., PMID:36830718
hnRNPH1 establishes Sertoli-germ cell crosstalk through cooperation with PTBP1 and AR, and is essential for male fertility in mice., PMID:36718792
A new Karyopherin-β2 binding PY-NLS epitope of HNRNPH2 is linked to neurodevelopmental disorders., PMID:36711837
The E3 Ligase TRIM25 Impairs Apoptotic Cell Death in Colon Carcinoma Cells via Destabilization of Caspase-7 mRNA: A Possible Role of hnRNPH1., PMID:36611995
Mutation-associated transcripts reconstruct the prognostic features of oral tongue squamous cell carcinoma., PMID:36593250
The identification and verification of hub genes associated with pulmonary arterial hypertension using weighted gene co-expression network analysis., PMID:36514015
SRSF3 and HNRNPH1 Regulate Radiation-Induced Alternative Splicing of Protein Arginine Methyltransferase 5 in Hepatocellular Carcinoma., PMID:36499164
Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis., PMID:36450980
In silico approaches uncovering the systematic function of N-phosphorylated proteins in human cells., PMID:36375414
hnRNPH1 recruits PTBP2 and SRSF3 to modulate alternative splicing in germ cells., PMID:35739118
HNRNPH1 destabilizes the G-quadruplex structures formed by G-rich RNA sequences that regulate the alternative splicing of an oncogenic fusion transcript., PMID:35639772
A novel HNRNPH1::ERG rearrangement in aggressive acute myeloid leukemia., PMID:35503261
Childhood acute myeloid leukemia with 5q deletion and HNRNPH1-MLLT10 fusion: the first case report., PMID:35139176
USP36 promotes tumor growth of non-small cell lung cancer via increasing KHK-A expression by regulating c-MYC-hnRNPH1/H2 axis., PMID:35133629
Etodolac improves collagen induced rheumatoid arthritis in rats by inhibiting synovial inflammation, fibrosis and hyperplasia., PMID:35006449
Distinct roles of hnRNPH1 low-complexity domains in splicing and transcription., PMID:34873036
Interconnected Gene Networks Underpin the Clinical Overlap of HNRNPH1-Related and Rubinstein-Taybi Intellectual Disability Syndromes., PMID:34759793
Proteomic Characterization of Colorectal Cancer Tissue from Patients Identifies Novel Putative Protein Biomarkers., PMID:34563043
For research use only. Not for human or drug use.
