Catalog No.
YHK92601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser2-Gly89
Predicted molecular weight
22.56 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96FJ2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Dynein light chain LC8-type 2, DLC2, 8 kDa dynein light chain b, DLC8b, Dynein light chain 2, cytoplasmic, DYNLL2
Higher expression of TSR2 aggravating hypertension via the PPAR signaling pathway., PMID:38814181
Aggrephagy-related gene signature correlates with survival and tumor-associated macrophages in glioma: Insights from single-cell and bulk RNA sequencing., PMID:38454689
Actl7b deficiency leads to mislocalization of LC8 type dynein light chains and disruption of murine spermatogenesis., PMID:37800308
Anoikis-Related Gene Signature for Prognostication of Pancreatic Adenocarcinoma: A Multi-Omics Exploration and Verification Study., PMID:37370756
Machine learning and integrative analysis identify the common pathogenesis of azoospermia complicated with COVID-19., PMID:37283758
Loss of MBNL1-mediated retrograde BDNF signaling in the myotonic dystrophy brain., PMID:36922901
Weighted gene co-expression network indicates that the DYNLL2 is an important regulator of chicken breast muscle development and is regulated by miR-148a-3p., PMID:35379193
Integrative bioinformatics approaches for identifying potential biomarkers and pathways involved in non-obstructive azoospermia., PMID:33532314
Integrative Analysis of Transcriptome-Wide Association Study and mRNA Expression Profiles Identifies Candidate Genes Associated With Idiopathic Pulmonary Fibrosis., PMID:33362862
Isolation and Culture of Primary Neurons and Glia from Adult Rat Urinary Bladder., PMID:32510511
Bioinformatics analysis revealed hub genes and pathways involved in sorafenib resistance in hepatocellular carcinoma., PMID:31698564
PI31 Is an Adaptor Protein for Proteasome Transport in Axons and Required for Synaptic Development., PMID:31327739
Dynein light chain binding determines complex formation and posttranslational stability of the Bcl-2 family members Bmf and Bim., PMID:31189926
Interactions of the dynein-2 intermediate chain WDR34 with the light chains are required for ciliary retrograde protein trafficking., PMID:30649997
Neospora caninum cytoplasmic dynein LC8 light chain 2 (NcDYNLL2) is differentially produced by pathogenically distinct isolates and regulates the host immune response., PMID:30561290
Interaction of WDR60 intermediate chain with TCTEX1D2 light chain of the dynein-2 complex is crucial for ciliary protein trafficking., PMID:29742051
The Drosophila LC8 homolog cut up specifies the axonal transport of proteasomes., PMID:28808087
Fasted/fed states regulate postsynaptic hub protein DYNLL2 and glutamatergic transmission in oxytocin neurons in the hypothalamic paraventricular nucleus., PMID:26344333
DYNLL2 dynein light chain binds to an extended linear motif of myosin 5a tail that has structural plasticity., PMID:25312846
ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis., PMID:25294941
Subunit composition of the human cytoplasmic dynein-2 complex., PMID:25205765
The stoichiometry of scaffold complexes in living neurons - DLC2 functions as a dimerization engine for GKAP., PMID:24938595
The novel zinc finger protein dASCIZ regulates mitosis in Drosophila via an essential role in dynein light-chain expression., PMID:24336747
A myosin-Va tail fragment sequesters dynein light chains leading to apoptosis in melanoma cells., PMID:23519116
GKAP-DLC2 interaction organizes the postsynaptic scaffold complex to enhance synaptic NMDA receptor activity., PMID:22328512
ERK2 phosphorylation of serine 77 regulates Bmf pro-apoptotic activity., PMID:22258404
SMRT analysis of MTOC and nuclear positioning reveals the role of EB1 and LIC1 in single-cell polarization., PMID:22193958
LC8 dynein light chain (DYNLL1) binds to the C-terminal domain of ATM-interacting protein (ATMIN/ASCIZ) and regulates its subcellular localization., PMID:21971545
DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond., PMID:21777386
The expression of dynein light chain DYNLL1 (LC8-1) is persistently downregulated in glaucomatous rat retinal ganglion cells., PMID:21145319
Affinity, avidity, and kinetics of target sequence binding to LC8 dynein light chain isoforms., PMID:20889982
Dynein light chain LC8 regulates syntaphilin-mediated mitochondrial docking in axons., PMID:19641106
CDK11p58 phosphorylation of PAK1 Ser174 promotes DLC2 binding and roles on cell cycle progression., PMID:19520772
An association analysis of murine anxiety genes in humans implicates novel candidate genes for anxiety disorders., PMID:18639233
The binding of DYNLL2 to myosin Va requires alternatively spliced exon B and stabilizes a portion of the myosin's coiled-coil domain., PMID:16981716
Identification of dynein light chain 2 as an interaction partner of p21-activated kinase 1., PMID:15845372
For research use only. Not for human or drug use.
