Catalog No.
YHA74801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-His151
Predicted molecular weight
20.25 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43683
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BUB1L, hBUB1, BUB1A, Mitotic checkpoint serine/threonine-protein kinase BUB1, BUB1
Identification of potential biomarkers associated with immune cell infiltration patterns in Kawasaki disease via bioinformatics., PMID:40455761
Interplay of kinetochores and catalysts drives rapid assembly of the mitotic checkpoint complex., PMID:40410156
Pan-cancer oncogenic properties and therapeutic potential of SF3B4., PMID:40394232
Identification of key biomarker genes in liver hepatocellular carcinoma and kidney renal clear cell carcinoma progression: A shared high-throughput screening and molecular docking method with potentials for targeted therapeutic interventions., PMID:40390492
FTO Promotes Hepatocellular Carcinoma Progression by Mediating m6A Modification of BUB1 and Targeting TGF-βR1 to Activate the TGF-β Signaling Pathway., PMID:40385944
A bioinformatics exploration of lung adenocarcinoma identifies hub genes with prognostic significance: from data to discovery., PMID:40320470
TMC5 as a Marker of Tumor-Associated Telocytes in Hepatocellular Carcinoma., PMID:40302342
Transcriptomic signatures of prostate cancer progression: a comprehensive RNA-seq study., PMID:40260408
Single-molecule tracking reveals the dynamic turnover of Ipl1 at the kinetochores in Saccharomyces cerevisiae., PMID:40250989
BUB1, miR-495-3p, and E2F1/E2F8 axis is associated with poor prognosis of breast cancer patients and infiltration of Th2 cells in the tumor microenvironment., PMID:40183319
Genome-wide CRISPR screen identifies BUB1 kinase as a druggable vulnerability in malignant pleural mesothelioma., PMID:40180891
PBK as a novel biomarker performed excellent diagnostic and prognostic value in HCC associated with immune infiltration and methylation., PMID:40178670
Discovering potential therapeutic targets in glioblastoma multiforme using a multi-omics approach., PMID:40168776
Identifcation of the FGF family as therapeutic targets and prognostic biomarkers in the microenvironment of head and neck squamous cell carcinoma., PMID:40086631
BUB1-deficiency suppresses kidney renal clear cell carcinoma progression via the PI3K/Akt pathway: A bioinformatics-oriented validating study., PMID:40081509
Developing a gene expression classifier for breast cancer diagnosis., PMID:40080330
A Comprehensive Analysis Revealing BUB1B as a Potential Prognostic and Immunological Biomarker in Lung Adenocarcinoma., PMID:40076684
Bulk transcriptome and single-nucleus RNA sequencing analyses highlight the role of recombination activating 1 in non-alcoholic fatty liver disease., PMID:40074128
BUB1 serves as a biomarker for poor prognosis in liver hepatocellular carcinoma., PMID:40069598
Pathogenic variants of BUB1 and BUBR1 genes are not prioritized in screening tests of couples with aborted aneuploid fetuses., PMID:40028477
Targeting the AURKB-MAD2L2 Axis Disrupts the DNA Damage Response and Glycolysis to Inhibit Colorectal Cancer Progression., PMID:40018943
Correction for Deng et al., The Arabidopsis BUB1/MAD3 family protein BMF3 requires BUB3.3 to recruit CDC20 to kinetochores in spindle assembly checkpoint signaling., PMID:40014562
Identification of Novel lncRNAs Related to Colorectal Cancer Through Bioinformatics Analysis., PMID:39949372
PICH impacts the spindle assembly checkpoint via its DNA translocase and SUMO-interaction activities., PMID:39919802
Integrative Bioinformatics Analysis for Targeting Hub Genes in Hepatocellular Carcinoma Treatment., PMID:39911278
Aneuploidy of specific chromosomes is beneficial to cells lacking spindle checkpoint protein Bub3., PMID:39903784
Exploring the mechanism and drug candidates of alveolar echinococcosis affecting liver fibrosis through analysis of existing microarray data., PMID:39863141
The dependence of shugoshin on Bub1-kinase activity is dispensable for the maintenance of spindle assembly checkpoint response in Cryptococcus neoformans., PMID:39804939
CENP-E haploinsufficiency causes chromosome misalignment and spindle assembly checkpoint activation in the spermatogonia., PMID:39737806
Identification and validation of KIF20A for predicting prognosis and treatment outcomes in patients with breast cancer., PMID:39733078
[Effect of overexpression of aldehyde dehydrogenase family member A2 on hypertrophic growth and proliferation of cardiomyocytes]., PMID:39722524
Identification of key signaling pathways and novel computational drug target for oral cancer, metabolic disorders and periodontal disease., PMID:39674633
Effect of COL11A1 on oral squamous cell carcinoma., PMID:39631528
Fibrous corona is reduced in cancer cell lines that attenuate microtubule nucleation from kinetochores., PMID:39604214
Exploring the Target Genes of Fucosylated Chondroitin Sulfate in Treating Lung Adenocarcinoma Based on the Integration of Bioinformatics Analysis, Molecular Docking, and Experimental Verification., PMID:39583738
A tale of two serines: the effects of histone H2A mutations S122A and S129A on chromosome nondisjunction in Saccharomyces cerevisiae., PMID:39558477
Self-priming of Plk1 binding to BubR1 ensures accurate mitotic progression., PMID:39516273
Establishment of prognosis model of hepatocellular carcinoma based on prognosis related gene analysis and study on gene regulation mechanism of model., PMID:39512465
BubR1 and SIRT2: Insights into aneuploidy, aging, and cancer., PMID:39490401
Generation and characterization of two isogenic induced pluripotent stem cell lines from a young female with microcephaly carrying a compound heterozygous mutation in BUB1 gene., PMID:39490209
DTL promotes the growth and migration of melanoma cells through the ERK/E2F1/BUB1 axis., PMID:39487277
Evaluation of BUBR1, MCM2, and GMNN as oral cancer biomarkers., PMID:39480819
Unveiling novel prognostic biomarkers and therapeutic targets for HBV-associated hepatocellular carcinoma through integrated bioinformatic analysis., PMID:39470543
Key genes and pathways in the molecular landscape of pancreatic ductal adenocarcinoma: A bioinformatics and machine learning study., PMID:39467488
Transcriptome Analysis Reveals the Early Development in Subcutaneous Adipose Tissue of Laiwu Piglets., PMID:39457885
BUB1 as a novel marker for predicting the immunotherapy efficacy and prognosis of breast cancer., PMID:39430818
Novel insights into the circadian modulation of lipid metabolism in chicken livers revealed by RNA sequencing and weighted gene co-expression network analysis., PMID:39361997
Cyclin A/Cdk1 promotes chromosome alignment and timely mitotic progression., PMID:39356777
CENP-C-targeted PLK-1 regulates kinetochore function in C. elegans embryos., PMID:39355896
Centromeres in cancer: Unraveling the link between chromosomal instability and tumorigenesis., PMID:39352464
For research use only. Not for human or drug use.
