Catalog No.
YHK92401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly221-Arg351
Predicted molecular weight
17.71 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q99856
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Bright, DRIL3, E2F-binding protein 1, ARID domain-containing protein 3A, ARID3A, DRX, E2FBP1, DRIL1, AT-rich interactive domain-containing protein 3A, B-cell regulator of IgH transcription, Dead ringer-like protein 1
ARID3A inhibits colorectal cancer cell stemness and drug-resistance by targeting a multitude of stemness-associated genes., PMID:40250751
Phosphorylation enhanced OTUD3 deubiquitination ARID3A promotes the progress of cholangiocarcinoma., PMID:40181152
Unveiling the prognostic value of ARID3A in breast cancer through bioinformatic analysis., PMID:40028521
LIN28B enhances the chemosensitivity of colon cancer cells via inducing genomic instability by upsetting the balance between the production and removal of reactive oxygen species., PMID:39986369
Disruption of the eEF1A1/ARID3A/PKC-δ Complex by Neferine Inhibits Macrophage Glycolytic Reprogramming in Atherosclerosis., PMID:39973763
Machine learning-driven identification of critical gene programs and key transcription factors in migraine., PMID:39833696
Aflatoxin B1 downregulates ARID3 genes to overcome senescence for inducing hepatocellular carcinoma., PMID:39366524
Exosomal let-7b-5p deriving from parietal epithelial cells attenuate renal fibrosis through suppression of TGFβR1 and ARID3a in obstructive kidney disease., PMID:39352691
ADAM interact with large protein complexes to regulate Histone modification, gene expression and splicing., PMID:39229132
Loss of ARID3A perturbs intestinal epithelial proliferation-differentiation ratio and regeneration., PMID:39150450
ARID3A enhances chemoresistance of pancreatic cancer via inhibiting PTEN-induced ferroptosis., PMID:38781729
Combining bulk and scRNA-seq to explore the molecular mechanisms governing the distinct efferocytosis activities of a macrophage subpopulation in PDAC., PMID:38501838
Uncovering co-regulatory modules and gene regulatory networks in the heart through machine learning-based analysis of large-scale epigenomic data., PMID:38354497
Reply to: "ARID3A variant and the risk of primary biliary cholangitis in a Central European cohort"., PMID:38301828
ARID3A variant and the risk of primary biliary cholangitis in a Central European cohort., PMID:38036008
ARID3A and ARID3B exert direct regulatory control over the long non-coding RNAs (lncRNAs) MALAT1 and NORAD within the context of non-small cell lung cancer (NSCLC)., PMID:37977034
Macrophages make a difference in cholestatic liver diseases - but how?, PMID:37821021
Exploration of common genomic signatures of systemic juvenile rheumatoid arthritis and type 1 diabetes., PMID:37704687
A+T rich interaction domain protein 3a (Arid3a) impairs Mertk-mediated efferocytosis in cholestasis., PMID:37659731
ARID3a from the ARID family: structure, role in autoimmune diseases and drug discovery., PMID:37488425
Integrated Analysis of miRNA and mRNA Regulation Network in Hypertension., PMID:37165183
A regulatory variant at 19p13.3 is associated with primary biliary cholangitis risk and ARID3A expression., PMID:36977669
DNA methylation patterns at birth predict health outcomes in young adults born very low birthweight., PMID:36959629
ARID3A plays a key regulatory role in palmitic acid-stimulated milk fat synthesis in mouse mammary epithelial cells., PMID:36786478
H3K36 methyltransferase NSD1 is essential for normal B1 and B2 cell development and germinal center formation., PMID:36532012
Several genetic variants associated with systemic sclerosis in a Chinese Han population., PMID:36301368
An integrative approach toward identification and analysis of therapeutic targets involved in HPV pathogenesis with a focus on carcinomas., PMID:36245368
miRNA let-7 family regulated by NEAT1 and ARID3A/NF-κB inhibits PRRSV-2 replication in vitro and in vivo., PMID:36215225
Hepatic ARID3A facilitates liver cancer malignancy by cooperating with CEP131 to regulate an embryonic stem cell-like gene signature., PMID:36008383
Discovery and Functional Characterization of Two Regulatory Variants Underlying Lupus Susceptibility at 2p13.1., PMID:35741778
A genome-wide CRISPR-Cas9 knockout screen identifies essential and growth-restricting genes in human trophoblast stem cells., PMID:35538076
Comprehensive analysis identified a reduction in ATP1A2 mediated by ARID3A in abdominal aortic aneurysm., PMID:35441443
Comprehensive Landscape of ARID Family Members and Their Association with Prognosis and Tumor Microenvironment in Hepatocellular Carcinoma., PMID:35402625
Copy Number Variation Analysis of Euploid Pregnancy Loss., PMID:35401693
Establishment and Comprehensive Analysis of Underlying microRNA-mRNA Interactive Networks in Ovarian Cancer., PMID:35310909
ARID3A promotes the chemosensitivity of colon cancer by inhibiting AKR1C3., PMID:35257428
MiR-361-3p promotes tumorigenesis of osteosarcoma cells via targeting ARID3A., PMID:35219069
Exosomal lncRNA HMMR-AS1 mediates macrophage polarization through miR-147a/ARID3A axis under hypoxia and affects the progression of hepatocellular carcinoma., PMID:35179300
Posttranscriptional Arid3a deregulation in AMKL., PMID:35113150
Somatic Mutations Enriched in Cis-Regulatory Elements Affect Genes Involved in Embryonic Development and Immune System Response in Neuroblastoma., PMID:35101866
ARID3A regulates autophagy related gene BECN1 expression and inhibits proliferation of osteosarcoma cells., PMID:34801937
Deficiencies in the DNA Binding Protein ARID3a Alter Chromatin Structures Important for Early Human Erythropoiesis., PMID:34663594
The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis., PMID:34570885
Identification and Validation of the Prognostic Stemness Biomarkers in Bladder Cancer Bone Metastasis., PMID:33816287
Lipid Rafts Interaction of the ARID3A Transcription Factor with EZRIN and G-Actin Regulates B-Cell Receptor Signaling., PMID:33804610
Distinct and overlapping roles of ARID3A and ARID3B in regulating E2F‑dependent transcription via direct binding to E2F target genes., PMID:33649863
ARID3A promotes the development of colorectal cancer by upregulating AURKA., PMID:33165575
TLR engagement induces ARID3a in human blood hematopoietic progenitors and modulates IFNα production., PMID:32979763
ARID3a expression in human hematopoietic stem cells is associated with distinct gene patterns in aged individuals., PMID:32905435
Long noncoding RNA ERICD interacts with ARID3A via E2F1 and regulates migration and proliferation of osteosarcoma cells., PMID:32749762
For research use only. Not for human or drug use.
