Catalog No.
YHB29401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met28-Lys221
Predicted molecular weight
24.29 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75715
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GSHPx-5, GPX5, Epididymal secretory glutathione peroxidase, EGLP, GPx-5, Glutathione peroxidase 5, Epididymis-specific glutathione peroxidase-like protein
Melatonin modulated GPX5 and PTGDS expression in Bactrian camel epididymis mainly via receptor MT1†., PMID:39951496
Isoglycyrrhizin supplementation of frozen goat semen-extender improves post-thaw sperm quality and in vitro fertilization rates., PMID:39693806
Identification and Validation of Oxidative Stress-Related Hub Genes in Parkinson's Disease., PMID:39556279
GPX5-Enriched Exosomes Improve Sperm Quality and Fertilization Ability., PMID:39408895
Development of a Normal Porcine Cell Line Growing in a Heme-Supplemented, Serum-Free Condition for Cultured Meat., PMID:38892012
Exploring novel function of Gpx5 antioxidant activity: Assisting epididymal cells secrete functional extracellular vesicles., PMID:38666419
Overexpression of Rhodiola crenulata glutathione peroxidase 5 increases cold tolerance and enhances the pharmaceutical value of the hairy roots., PMID:38615983
Alleviation of carbendazim toxicity effect by Moringa oleifera oil and Linum usitatissimum L. oil on testes of male rats: Physiological, histological and in silico study., PMID:38268782
Abundance of selected genes implicated in testicular functions in Camelus dromedarius with high and low epididymal semen quality., PMID:38145478
Proteomic analysis of boar sperm with differential ability of liquid preservation at 17 °C., PMID:38029685
Association of PCSK1 and PPARG1 Allelic Variants with Obesity and Metabolic Syndrome in Mexican Adults., PMID:37761915
Glutathione Peroxidase gpx1 to gpx8 Genes Expression in Experimental Brain Tumors Reveals Gender-Dependent Patterns., PMID:37761814
Differential expression and localisation of heat shock protein 70 (HSP70) and glutathione peroxidase 5 (GPX5) in the testis and epididymis of Sonid Bactrian camels., PMID:37290785
Alleviation of cadmium-induced photoinhibition and oxidative stress by melatonin in Chlamydomonas reinhardtii., PMID:37269507
Simvastatin ameliorates testosterone-induced prostatic hyperplasia in rats via modulating IGF-1/PI3K/AKT/FOXO signaling., PMID:37164119
Research progress of glutathione peroxidase family (GPX) in redoxidation., PMID:36937839
Translatomics and physiological analyses of the detoxification mechanism of green alga Chlamydomonas reinhardtii to cadmium toxicity., PMID:36860060
Aberrant gene expression of superoxide dismutases in Chlamydia trachomatis-infected recurrent spontaneous aborters., PMID:36038649
β-Cyclocitral Does Not Contribute to Singlet Oxygen-Signalling in Algae, but May Down-Regulate Chlorophyll Synthesis., PMID:36015457
miR-542-3p reduces antioxidant capacity in goat caput epididymal epithelial cells by targeting glutathione peroxidase 5 (GPx5)., PMID:35487118
Simvastatin as an emerging pollutant on non-target aquatic invertebrates: effects on antioxidant-related genes in Daphnia magna., PMID:35258724
Trehalose can effectively protect sheep epididymis epithelial cells from oxidative stress., PMID:34458560
Effect of Boar Sperm Proteins and Quality Changes on Field Fertility., PMID:34204554
Effects of cypermethrin on the hepatic transcriptome and proteome of the red claw crayfish Cherax quadricarinatus., PMID:33297066
Potential relationship between the selenoproteome and cancer., PMID:33133596
Impact of diabetic hyperglycaemia and insulin therapy on autophagy and impairment in rat epididymis., PMID:33125789
The glutathione peroxidase family of Theobroma cacao: Involvement in the oxidative stress during witches' broom disease., PMID:32882281
Glutathione peroxidase 5 deficiency induces lipid metabolism regulated by reactive oxygen species in Chlamydomonas reinhardtii., PMID:32599138
Transcriptomic and Physiological Responses to Oxidative Stress in a Chlamydomonas reinhardtii Glutathione Peroxidase Mutant., PMID:32344528
Knockout of glutathione peroxidase 5 down-regulates the piRNAs in the caput epididymidis of aged mice., PMID:32270769
Zinc deficient diet exacerbates the testicular and epididymal damage in type 2 diabetic rat: Studies on oxidative stress-related mechanisms., PMID:32245730
Comparative proteomics reveals protective effect of resveratrol on a high-fat diet-induced damage to mice testis., PMID:31955635
Proteome of cat semen obtained after urethral catheterization., PMID:31518731
Testosterone promotes GPX5 expression of goat epididymal epithelial cells cultured in vitro., PMID:31429037
Proteomic markers of low and high fertility bovine spermatozoa separated by Percoll gradient., PMID:31134708
Antioxidant enzyme expression of mRNA and protein in the epididymis of finasteride-treated male rat offspring during postnatal development., PMID:31110548
In silico analysis of caprine superoxide dismutase 1 (SOD1) gene., PMID:30684533
The role of vitamin C in the gene expression of oxidative stress markers in fibroblasts from burn patients., PMID:30208132
Expression of selenium-independent glutathione peroxidase 5 (GPx5) in the epididymis of Small Tail Han sheep., PMID:29642666
Extender Supplementation with Antioxidants Selected after the Evaluation of Sperm Susceptibility to Oxidative Challenges in Goats., PMID:29382256
Proteomic Markers of Functional Sperm Population in Bovines: Comparison of Low- and High-Density Spermatozoa Following Cryopreservation., PMID:29148792
Chlamydomonas reinhardtii responding to high light: a role for 2-propenal (acrolein)., PMID:28326554
Methotrexate-induced germ cell toxicity and the important role of zinc and SOD1: Investigation of molecular mechanisms., PMID:28011267
Glutathione Peroxidase 5 Is Expressed by the Entire Pig Male Genital Tract and Once in the Seminal Plasma Contributes to Sperm Survival and In Vivo Fertility., PMID:27627110
Role of Zinc Supplementation in Testicular and Epididymal Damages in Diabetic Rat: Involvement of Nrf2, SOD1, and GPX5., PMID:27025721
Copper-Induced Spermatozoa Head Malformation Is Related to Oxidative Damage to Testes in CD-1 Mice., PMID:27025717
A novel antioxidant formulation designed to treat male infertility associated with oxidative stress: promising preclinical evidence from animal models., PMID:26732620
Triosephosphate isomerase (TPI) and epididymal secretory glutathione peroxidase (GPX5) are markers for boar sperm quality., PMID:26711247
Comparative analysis of boar seminal plasma proteome from different freezability ejaculates and identification of Fibronectin 1 as sperm freezability marker., PMID:25678437
Mitochondrial dysfunction in primary human fibroblasts triggers an adaptive cell survival program that requires AMPK-α., PMID:25536029