Catalog No.
YHG54101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro1691-Ala1916
Predicted molecular weight
27.75 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13459
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MYO9B, Unconventional myosin-IXb, MYR5, Unconventional myosin-9b
RhoA GAP Myo9b regulates β2-integrin activity and neutrophil recruitment during murine acute kidney injury., PMID:40504998
First Iranian Family with a Novel Missense Variant in MYO9B Gene Causing Charcot-Marie-Tooth Disease., PMID:40382695
Exploring the spatio-temporal dynamics in activator-inhibitor systems through a dual approach of analysis and computation., PMID:40316164
Myosin IXB protects immune cells from virus infection., PMID:40167026
Identification of mitophagy-related key genes and their correlation with immune cell infiltration in acute myocardial infarction via bioinformatics analysis., PMID:39872885
MIRO2 promotes cancer invasion and metastasis via MYO9B suppression of RhoA activity., PMID:39723893
Proteogenomic characterization of difficult-to-treat breast cancer with tumor cells enriched through laser microdissection., PMID:38745208
A liquid biomarker signature of inflammatory proteins accurately predicts early pancreatic cancer progression during FOLFIRINOX chemotherapy., PMID:38335839
Myo9b mutations are associated with altered dendritic cell functions and increased susceptibility to autoimmune diabetes onset., PMID:37749140
Mutations in MYO9B are associated with Charcot-Marie-Tooth disease type 2 neuropathies and isolated optic atrophy., PMID:36260368
The RhoGAP-myosin Myo9b regulates ocular lens pit morphogenesis., PMID:36008362
Effect of Monoacylglycerol Lipase Inhibition on Intestinal Permeability of Rats With Severe Acute Pancreatitis., PMID:35496266
Donor genetic and nongenetic factors affecting red blood cell transfusion effectiveness., PMID:34793330
A proteomic analysis of the effect of ocean acidification on the haemocyte proteome of the South African abalone Haliotis midae., PMID:34411749
Dietary Grape Seed Meal Bioactive Compounds Alleviate Epithelial Dysfunctions and Attenuates Inflammation in Colon of DSS-Treated Piglets., PMID:33806347
Transcriptome profiles discriminate between Gram-positive and Gram-negative sepsis in preterm neonates., PMID:33767373
Local Myo9b RhoGAP activity regulates cell motility., PMID:33268376
TSAd Plays a Major Role in Myo9b-Mediated Suppression of Malignant Pleural Effusion by Regulating TH1/TH17 Cell Response., PMID:33046503
The RhoA regulators Myo9b and GEF-H1 are targets of cyclic nucleotide-dependent kinases in platelets., PMID:32692911
Class IX Myosins: Motorized RhoGAP Signaling Molecules., PMID:32451867
Spatial proteomics revealed a CX3CL1-dependent crosstalk between the urothelium and relocated macrophages through IL-6 during an acute bacterial infection in the urinary bladder., PMID:32112048
The RhoGAP HUM-7/Myo9 integrates signals to modulate RHO-1/RhoA during embryonic morphogenesis in Caenorhabditiselegans., PMID:30389847
The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8+ T cells., PMID:29875261
Relationships of bone characteristics in MYO9B deficient femurs., PMID:29754047
An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns., PMID:29055010
Analysis of PTPN22, ZFAT and MYO9B polymorphisms in Turner Syndrome and risk of autoimmune disease., PMID:28627089
The RhoGAP Myo9b Promotes Bone Growth by Mediating Osteoblastic Responsiveness to IGF-1., PMID:28585695
Inhibition of KLF5-Myo9b-RhoA Pathway-Mediated Podosome Formation in Macrophages Ameliorates Abdominal Aortic Aneurysm., PMID:28115390
MYO9B gene polymorphisms are associated with the risk of inflammatory bowel diseases., PMID:27556856
The broad spectrum of celiac disease and gluten sensitive enteropathy., PMID:27547052
A meta-analysis of the relationship between MYO9B gene polymorphisms and susceptibility to Crohn's disease and ulcerative colitis., PMID:27435931
Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism., PMID:27363609
Lack of Association between MYO9B Gene Polymorphisms and Susceptibility to Coeliac Disease in Caucasians: Evidence from a Meta-Analysis., PMID:27219348
Mice lacking myosin IXb, an inflammatory bowel disease susceptibility gene, have impaired intestinal barrier function and superficial ulceration in the ileum., PMID:26972322
Specific Myosins Control Actin Organization, Cell Morphology, and Migration in Prostate Cancer Cells., PMID:26670045
Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression., PMID:26529257
The motorized RhoGAP myosin IXb (Myo9b) in leukocytes regulates experimental autoimmune encephalomyelitis induction and recovery., PMID:25903725
Lack of genetic association between the MYO9B locus and schizophrenia in a Chinese population., PMID:25710847
The JNK1/JNK3 interactome--contributions by the JNK3 unique N-terminus and JNK common docking site residues., PMID:25301550
Mouse macrophages completely lacking Rho subfamily GTPases (RhoA, RhoB, and RhoC) have severe lamellipodial retraction defects, but robust chemotactic navigation and altered motility., PMID:25213860
Myosin IXb variants and their pivotal role in maintaining the intestinal barrier: a study in Crohn's disease., PMID:25098938
Association of MYO9B gene polymorphisms with inflammatory bowel disease in Chinese Han population., PMID:24966617
Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians., PMID:24647736
Dendritic cell motility and T cell activation requires regulation of Rho-cofilin signaling by the Rho-GTPase activating protein myosin IXb., PMID:24646736
The RhoGAP activity of myosin IXB is critical for osteoclast podosome patterning, motility, and resorptive capacity., PMID:24466350
Association analysis of genetic variants in the myosin IXB gene in acute pancreatitis., PMID:24386489
Frequency of MYO9B polymorphisms in celiac patients and controls., PMID:23368647
Myosins in cell junctions., PMID:22954512
Myo9B is associated with an increased risk of Barrett's esophagus and esophageal adenocarcinoma., PMID:22954106
A role for myosin IXb, a motor-RhoGAP chimera, in epithelial wound healing and tight junction regulation., PMID:22573889
For research use only. Not for human or drug use.
