Catalog No.
YHC45601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser19-Val128
Predicted molecular weight
14.16 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P0C0S5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Histone H2A.Z, H2AZ1, H2AZ, H2A/z, H2AFZ
Coupling deep phenotypic quantification with next-generation phenotyping for 192 individuals with germline histonopathies., PMID:40241305
Srcap loss alters H2A.Z-dependent and neuronal differentiation-related gene expression in N2A cells., PMID:40068207
The INO80 Chromatin Remodeling Complex Regulates Histone H2A.Z Mobility and the G1-S Transition in Oligodendrocyte Precursors., PMID:40017313
Investigating the Impact of Circulating MicroRNAs on Knee and Hip Osteoarthritis: Causal Links, Biological Mechanisms, and Drug Interactions., PMID:39796139
Histone variant H2AZ1 drives lung cancer progression through the RELA-HIF1A-EGFR signaling pathway., PMID:39327549
CRISPR-based screening pinpoints H2AZ1 as a driver of senescence in human mesenchymal stem cells., PMID:38894586
Role of the histone variant H2A.Z.1 in memory, transcription, and alternative splicing is mediated by lysine modification., PMID:38366138
Identification and validation of an H2AZ1-based index model: a novel prognostic tool for hepatocellular carcinoma., PMID:38305811
H2A.Z is involved in premature aging and DSB repair initiation in muscle fibers., PMID:38281187
Behavioral and transcriptional effects of repeated electroconvulsive seizures in the neonatal MK-801-treated rat model of schizophrenia., PMID:38081977
Comprehensive bioinformatic analysis reveals oncogenic role of H2A.Z isoforms in cervical cancer progression., PMID:35317119
Structural basis of chromatin regulation by histone variant H2A.Z., PMID:34643712
Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survival., PMID:34525369
INO80 promotes H2A.Z occupancy to regulate cell fate transition in pluripotent stem cells., PMID:34139016
A dual role for H2A.Z.1 in modulating the dynamics of RNA polymerase II initiation and elongation., PMID:33972784
Genome-wide chromatin accessibility is restricted by ANP32E., PMID:33033242
CpG Islands Shape the Epigenome Landscape., PMID:33010306
Histone H2A.Z is required for androgen receptor-mediated effects on fear memory., PMID:32916283
Sex-specific effects of the histone variant H2A.Z on fear memory, stress-enhanced fear learning and hypersensitivity to pain., PMID:32868857
Histone variant H2A.Z regulates nucleosome unwrapping and CTCF binding in mouse ES cells., PMID:32392318
H2A.Z is dispensable for both basal and activated transcription in post-mitotic mouse muscles., PMID:32266374
Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain., PMID:31712428
The base pair-scale diffusion of nucleosomes modulates binding of transcription factors., PMID:31147470
Znhit1 controls intestinal stem cell maintenance by regulating H2A.Z incorporation., PMID:30842416
Histone variants H2A.Z and H3.3 coordinately regulate PRC2-dependent H3K27me3 deposition and gene expression regulation in mES cells., PMID:30249243
H2A.Z.1 crosstalk with H3K56-acetylation controls gliogenesis through the transcription of folate receptor., PMID:29982651
Transcriptional regulation mediated by H2A.Z via ANP32e-dependent inhibition of protein phosphatase 2A., PMID:29524612
Learning and Age-Related Changes in Genome-wide H2A.Z Binding in the Mouse Hippocampus., PMID:29386101
Brain-specific deletion of histone variant H2A.z results in cortical neurogenesis defects and neurodevelopmental disorder., PMID:29294103
Conventional and pioneer modes of glucocorticoid receptor interaction with enhancer chromatin in vivo., PMID:29126175
SMYD3-Mediated H2A.Z.1 Methylation Promotes Cell Cycle and Cancer Proliferation., PMID:27569210
H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs., PMID:26804911
For research use only. Not for human or drug use.
