Catalog No.
YHF11801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn58-Asp260
Predicted molecular weight
24.87 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P55285
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
K-cadherin, CDH6, Cadherin-6, Kidney cadherin
TRIM29 upregulation contributes to chemoresistance in triple negative breast cancer via modulating S100P-β-catenin axis., PMID:40420099
N6-methyladenosine-modified circ_0000517 promotes non-small cell lung cancer metastasis via miR-1233-3p/CDH6 axis., PMID:40278968
Novel serum biomarker associations with 7 Tesla MRI-defined cortical lesions, leptomeningeal enhancement, and deep gray matter volume in early multiple sclerosis., PMID:40200016
Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility., PMID:40193178
Oncology Clinical Trials Targeting Members of the Cadherin Superfamily: A Review., PMID:39811419
Antibody-drug conjugates as targeted therapy for treating gynecologic cancers: update 2025., PMID:39480912
Mesothelin promotes the migration of endometrioid carcinoma and is associated with the MELF pattern., PMID:39182448
PAX8 expression in cancerous and non-neoplastic tissue: a tissue microarray study on more than 17,000 tumors from 149 different tumor entities., PMID:39105782
Targeting alternative splicing of fibronectin in human renal proximal tubule epithelial cells with antisense oligonucleotides to reduce EDA+ fibronectin production and block an autocrine loop that drives renal fibrosis., PMID:39098465
Comparative Transcriptome Analysis of the Hypothalamic-Pituitary-Gonadal Axis of Jinhu Grouper (Epinephelus fuscoguttatus ♀ × Epinephelus tukula ♂) and Tiger Grouper (Epinephelus fuscoguttatus)., PMID:39062708
Cadherin-6 is a novel mediator for the migration of mesenchymal stem cells to glioblastoma cells in response to stromal cell-derived factor-1., PMID:38719785
POU6F2, a risk factor for glaucoma, myopia and dyslexia, labels specific populations of retinal ganglion cells., PMID:38698014
Neurotensin modulates ovarian vascular permeability via adherens junctions., PMID:38581236
The Impact of Transcriptional Profiling Cadherin Family and Therapeutic Approaches of Gastric Cancer: A Translational Outlook on Multi-omics Data Analysis., PMID:38530538
SOX9 switch links regeneration to fibrosis at the single-cell level in mammalian kidneys., PMID:38386758
The knockdown of stathmin with si-RNA inhibits invasion of mesothelioma., PMID:38244401
Raludotatug Deruxtecan, a CDH6-Targeting Antibody-Drug Conjugate with a DNA Topoisomerase I Inhibitor DXd, Is Efficacious in Human Ovarian and Kidney Cancer Models., PMID:38205802
Screening tumor stage-specific candidate neoantigens in thyroid adenocarcinoma using integrated exome and transcriptome sequencing., PMID:37854594
Glycyl-tRNA Synthetase Induces Psoriasis-Like Skin by Facilitating Skin Inflammation and Vascular Endothelial Cell Angiogenesis., PMID:37827278
The GLI2/CDH6 axis enhances migration, invasion and mitochondrial fission of stomach adenocarcinoma cells., PMID:37523816
Effects of indented zona pellucida on oocyte growth and development explored from changes of gene expression in cumulus cells., PMID:37400728
Association of muscular strength and targeted proteomics involved in brain health in children with overweight/obesity., PMID:37190796
Longitudinal transcriptomic analysis of mouse sciatic nerve reveals pathways associated with age-related muscle pathology., PMID:36905126
Molecular characterization of early breast cancer onset to understand disease phenotypes in African patients., PMID:36352274
CDH6 as a prognostic indicator and marker for chemotherapy in gliomas., PMID:35938030
Two distinct receptor-binding domains of human glycyl-tRNA synthetase 1 displayed on extracellular vesicles activate M1 polarization and phagocytic bridging of macrophages to cancer cells., PMID:35523311
Construction and Characterization of Cadherin 6 (CDH6)-Targeting Chimeric Antigen Receptor (CAR) Modified T Cells., PMID:35378004
Molecular Characterization of Differentiated-Resistance MSC Subclones by Single-Cell Transcriptomes., PMID:35356283
Dietary mulberry-leaf flavonoids improve the eggshell quality of aged breeder hens., PMID:34883395
Identification and verification of the molecular mechanisms and prognostic values of the cadherin gene family in gastric cancer., PMID:34880371
Non-Pigmented Ciliary Epithelium-Derived Extracellular Vesicles Loaded with SMAD7 siRNA Attenuate Wnt Signaling in Trabecular Meshwork Cells In Vitro., PMID:34577558
MicroRNA Dysregulation in the Hippocampus of Rats with Noise-Induced Hearing Loss., PMID:34527169
A Phase 1 Study of a CDH6-Targeting Antibody-Drug Conjugate in Patients with Advanced Solid Tumors with Evaluation of Inflammatory and Neurological Adverse Events., PMID:34515215
Extracellular vesicle-derived AEBP1 mRNA as a novel candidate biomarker for diabetic kidney disease., PMID:34332599
CDH6-activated αIIbβ3 crosstalks with α2β1 to trigger cellular adhesion and invasion in metastatic ovarian and renal cancers., PMID:33715292
ESMO20 YO for YO: highlights on adjuvant CDK4/6 inhibitors in early hormone receptor-positive/HER2-negative breast cancer., PMID:33399079
Total Platelet Transcriptomics and Its Network Analysis by RNA-Seq and miRNA-Seq and PCA Application in Essential Thrombocythaemia., PMID:33227791
Somatic mutational landscapes of adherens junctions and their functional consequences in cutaneous melanoma development., PMID:33204327
Redundant type II cadherins define neuroepithelial cell states for cytoarchitectonic robustness., PMID:33060832
Protein signatures from blood plasma and urine suggest changes in vascular function and IL-12 signaling in elderly with a history of chronic diseases compared with an age-matched healthy cohort., PMID:32974878
Mitophagy in degenerative joint diseases., PMID:32967533
Hnf4a Is Required for the Development of Cdh6-Expressing Progenitors into Proximal Tubules in the Mouse Kidney., PMID:32764140
Characterization of the role for cadherin 6 in the regulation of human endometrial receptivity., PMID:32600462
Tryptophanyl-tRNA Synthetase, a Novel Damage-Induced Cytokine, Significantly Increases the Therapeutic Effects of Endometrial Stem Cells., PMID:32592690
Linc00941 Is a Novel Transforming Growth Factor β Target That Primes Papillary Thyroid Cancer Metastatic Behavior by Regulating the Expression of Cadherin 6., PMID:32495722
CDH6 and HAGH protein levels in plasma associate with Alzheimer's disease in APOE ε4 carriers., PMID:32427856
IFN-κ suppresses the replication of influenza A viruses through the IFNAR-MAPK-Fos-CHD6 axis., PMID:32265337
Multi-platform Affinity Proteomics Identify Proteins Linked to Metastasis and Immune Suppression in Ovarian Cancer Plasma., PMID:31737572
The Interaction of Platelets with Colorectal Cancer Cells Inhibits Tumor Growth but Promotes Metastasis., PMID:31727628
Transcriptional profiling of the murine intervertebral disc and age-associated changes in the nucleus pulposus., PMID:31597481
For research use only. Not for human or drug use.
