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Recombinant Human RNASE3 Protein, N-His-SUMO

Catalog #:   YHC94602 Specific References (99) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P12724
Protein length: Pro30-Ile160
Overview

Catalog No.

YHC94602

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Pro30-Ile160

Predicted molecular weight

27.61 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P12724

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

RNase 3, ECP, Eosinophil cationic protein, RNS3, Ribonuclease 3, RNASE3

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Human RNASE3 protein
References

Viral RNase3 Co-Localizes and Interacts with the Antiviral Defense Protein SGS3 in Plant Cells. PMID: 27391019

Associations Between Inflammatory Endotypes and Clinical Presentations in Chronic Rhinosinusitis. PMID: 31128376

Genetic variants of RNASE3 (ECP) and susceptibility to severe malaria in Senegalese population. PMID: 29402293

Human RNase3 immune modulation by catalytic-dependent and independent modes in a macrophage-cell line infection model. PMID: 33226440

Positional scanning library applied to the human eosinophil cationic protein/RNase3 N-terminus reveals novel and potent anti-biofilm peptides. PMID: 29763807

Bioinformatics analysis and identification of hub genes and immune-related molecular mechanisms in chronic myeloid leukemia. PMID: 35111390

Polymorphisms in the RNASE3 gene are associated with susceptibility to cerebral malaria in Ghanaian children. PMID: 22216286

Identification of polymorphisms in the RNase3 gene and the association with allergic rhinitis. PMID: 19760211

Binding and processing of small dsRNA molecules by the class 1 RNase III protein encoded by sweet potato chlorotic stunt virus. PMID: 24187016

Genetic variability and evolutionary implications of RNA silencing suppressor genes in RNA1 of sweet potato chlorotic stunt virus isolates infecting sweetpotato and related wild species. PMID: 24278443

Eosinophil cationic protein--current concepts and controversies. PMID: 22135850

Eosinophil cationic protein (ECP) polymorphisms and association with asthma, s-ECP levels and related phenotypes. PMID: 17362255

Elimination of antiviral defense by viral RNase III. PMID: 19515815

Cellular and noncellular bloodborne biomarkers in asthma. PMID: 28583261

Identification of novel genes influencing eosinophil-specific protein levels in asthma families. PMID: 35671886

Viral class 1 RNase III involved in suppression of RNA silencing. PMID: 15890961

Sputum Proteomics in Nontuberculous Mycobacterial Lung Disease. PMID: 34838525

Eosinophil Cationic Protein, Carotid Plaque, and Incidence of Stroke. PMID: 28904229

In silico prediction and in vitro characterization of multifunctional human RNase3. PMID: 23484086

Clara cell protein 16 and eosinophil cationic protein production in chronically inflamed sinonasal mucosa. PMID: 26833624

Airway Surfactant Protein D Deficiency in Adults With Severe Asthma. PMID: 26836907

Eosinophil cationic protein mRNA expression in children with bronchial asthma. PMID: 26600485

Maternal circulating metabolic biomarkers and their prediction performance for gestational diabetes mellitus related macrosomia. PMID: 36788507

Integral Analysis of the RNA Binding Protein-associated Prognostic Model for Renal Cell Carcinoma. PMID: 33456353

Antimicrobial Role of RNASET2 Protein During Innate Immune Response in the Medicinal Leech Hirudo verbana. PMID: 32210967

Eosinophil cationic protein is a potential surrogate marker of allergic contact dermatitis: A single-center, retrospective study of 216 patients. PMID: 32442701

Eosinophil Cationic Protein in Patients with Differentiated Thyroid Cancer Treated with Radioactive Iodine 131. PMID: 29066479

[Cow's milk protein allergy through human milk]. PMID: 22226014

Utility of eosinophil cationic protein levels in the diagnosis of intrinsic atopic dermatitis. PMID: 24129707

Cell Penetrating Peptide Derived from Human Eosinophil Cationic Protein Decreases Airway Allergic Inflammation. PMID: 28955044

[Expression of LC3 and ECP in allergic rhinitis and their significance]. PMID: 30970402

Human Antimicrobial RNases Inhibit Intracellular Bacterial Growth and Induce Autophagy in Mycobacteria-Infected Macrophages. PMID: 31312205

A biologically inspired lung-on-a-chip device for the study of protein-induced lung inflammation. PMID: 25486073

Protein post-translational modification in host defense: the antimicrobial mechanism of action of human eosinophil cationic protein native forms. PMID: 25271100

Eosinophil protein in airway macrophages: a novel biomarker of eosinophilic inflammation in patients with asthma. PMID: 20639010

Asparagine-linked glycans determine the cytotoxic capacity of eosinophil cationic protein (ECP). PMID: 23597768

Development and validation of a RNA binding protein-associated prognostic model for head and neck squamous cell carcinoma. PMID: 33758106

C-reactive protein levels in the serum of asthmatic patients. PMID: 17650829

The Correlation of Serum Myeloid-Related Protein-8/14 and Eosinophil Cationic Protein in Patients with Coronary Artery Disease. PMID: 27022611

Serum eosinophil cationic protein and 27 cytokines/chemokines in acute exacerbation of childhood asthma. PMID: 20523065

Exploring new biological functions of amyloids: bacteria cell agglutination mediated by host protein aggregation. PMID: 23133388

Neutrophils as a novel source of eosinophil cationic protein in IgE-mediated processes. PMID: 17675527

Identification and validation of seven RNA binding protein genes as a prognostic signature in oral cavity squamous cell carcinoma. PMID: 34585646

Cytokine expression in human dermal fibroblasts stimulated with eosinophil cationic protein measured by protein array. PMID: 24383969

The role of eosinophil cationic protein in patients with Mycoplasma pneumoniae infection. PMID: 18218558

Eosinophil cationic protein stimulates TGF-beta1 release by human lung fibroblasts in vitro. PMID: 17587163

Saliva and serum eosinophil cationic protein in asthmatic children and adolescents with and without allergic sensitization. PMID: 20100023

Pre-intervention eosinophil cationic protein serum levels predict clinical outcomes following implantation of drug-eluting stents. PMID: 19383735

Eosinophil cationic protein damages protoscoleces in vitro and is present in the hydatid cyst. PMID: 16879306

Serum eosinophil cationic protein and CD23 in acute RSV bronchiolitis. PMID: 16192901

Membrane-bound carboxypeptidase E facilitates the entry of eosinophil cationic protein into neuroendocrine cells. PMID: 15233624

Two human host defense ribonucleases against mycobacteria, the eosinophil cationic protein (RNase 3) and RNase 7. PMID: 23716047

Clinical Features of Ocular Toxocariasis in Adult Korean Patients. PMID: 25564736

Unique peptide identification of RNase A superfamily sequences based on reinforced merging algorithms. PMID: 16568543

Signal peptide of eosinophil cationic protein upregulates transforming growth factor-alpha expression in human cells. PMID: 17063486

Faecal and serum levels of eosinophil cationic protein in a healthy paediatric population. PMID: 17852809

RNase 3 (ECP) is an extraordinarily stable protein among human pancreatic-type RNases. PMID: 12417023

Fecal assays detect hypersensitivity to cow's milk protein and gluten in adults with irritable bowel syndrome. PMID: 21839707

Correlation between miR-223 and IL-35 and their regulatory effect in children with allergic rhinitis. PMID: 32169441

Synergistic interactions of begomoviruses with Sweet potato chlorotic stunt virus (genus Crinivirus) in sweet potato (Ipomoea batatas L.). PMID: 25187172

The cytotoxicity of eosinophil cationic protein/ribonuclease 3 on eukaryotic cell lines takes place through its aggregation on the cell membrane. PMID: 18087674

Adenoid hypetrophy: definition of some risk factors. PMID: 22691244

Association Between Pollen Exposure and Nasal Cytokines in Grass Pollen-Allergic Children. PMID: 28731413

Association of periostin expression with eosinophilic inflammation in nasal polyps. PMID: 26521039

Rationally Modified Antimicrobial Peptides from the N-Terminal Domain of Human RNase 3 Show Exceptional Serum Stability. PMID: 34342438

The 434(G>C) polymorphism in the eosinophil cationic protein gene and its association with tissue eosinophilia in oral squamous cell carcinomas. PMID: 19566743

Urine leukotriene E and eosinophil cationic protein in nasopharyngeal aspiration from young wheezy children. PMID: 16101934

The (1)H, (13)C, (15)N resonance assignment, solution structure, and residue level stability of eosinophil cationic protein/RNase 3 determined by NMR spectroscopy. PMID: 19189375

The negative regulation of piscine CD44c in viral and bacterial infection. PMID: 30885554

Evidence for eosinophil degranulation in acute appendicitis. PMID: 18603674

Transcriptional regulation of human eosinophil RNase2 by the liver-enriched hepatocyte nuclear factor 4. PMID: 19115260

Differential extraction of eosinophil granule proteins. PMID: 16257006

Leptin and Atopic Dermatitis in Korean Elementary School Children. PMID: 27090367

Insights into the Antimicrobial Mechanism of Action of Human RNase6: Structural Determinants for Bacterial Cell Agglutination and Membrane Permeation. PMID: 27089320

IP-10 Is Elevated in Virus-Induced Acute Exacerbations in Childhood Asthma. PMID: 27988920

A SELDI-TOF MS study of the genetic and post-translational molecular heterogeneity of eosinophil cationic protein. PMID: 17726151

Neutrophil biomarkers predict response to therapy with tumor necrosis factor inhibitors in rheumatoid arthritis. PMID: 27733572

T-lymphocyte activation and the levels of eosinophilic cationic protein and interleukin-5 in asthmatic children with acute exacerbation and effect of glucocorticoid treatment. PMID: 16948352

Percentage of eosinophils with surface CD44 and levels of eosinophil cationic protein in the peripheral blood in children with bronchial asthma and their changes after montelukast therapy. PMID: 16948353

Transcription factor CEBPB inhibits the proliferation of osteosarcoma by regulating downstream target gene CLEC5A. PMID: 31364785

Sputum eosinophilia in idiopathic pulmonary fibrosis. PMID: 15750711

Conformational transitions in eosinophil cationic protein: a molecular dynamics study in aqueous environment. PMID: 15317478

Comparison of viral load in individuals with and without asthma during infections with rhinovirus. PMID: 24471509

The production of the eosinophil proteins ECP and EPX/EDN are regulated in a reciprocal manner. PMID: 24738159

Bactericidal and membrane disruption activities of the eosinophil cationic protein are largely retained in an N-terminal fragment. PMID: 19450231

Association between eosinophilic airway inflammation and persistent airflow limitation. PMID: 23414249

[Expression of T-bet and its relation with IgE and eosinophil cationic protein in patients with allergic rhinitis]. PMID: 16874959

A Heparan Sulfate-Binding Cell Penetrating Peptide for Tumor Targeting and Migration Inhibition. PMID: 26064887

Association of atopic dermatitis with obesity via a multi-omics approach: A protocol for a case-control study. PMID: 31335732

CEACAM3 decreases asthma exacerbations and modulates respiratory syncytial virus latent infection in children. PMID: 32606071

Whole-exome sequencing uncovers frequent GNAS mutations in intraductal papillary mucinous neoplasms of the pancreas. PMID: 22355676

Three-dimensional crystal structure of human eosinophil cationic protein (RNase 3) at 1.75 A resolution. PMID: 10903870

Exhaled nitric oxide predicts eosinophilic airway inflammation in COPD. PMID: 24816967

Co-existence of chronic urticaria and metabolic syndrome: clinical implications. PMID: 22948845

Characterization of the angiogenic activity of zebrafish ribonucleases. PMID: 19549190

Vascular endothelial growth factor in allergen-induced nasal inflammation. PMID: 19236408

Cloning and expression of P67 protein of Mycoplasma leachii. PMID: 29062201

Enhanced hydrolysis of lignocellulosic biomass with doping of a highly thermostable recombinant laccase. PMID: 31260768

Production of an Antibody Fragment (scFv) Targeting PcrV Protein of Pseudomonas aeruginosa in Fed-Batch Cultivation Mode. PMID: 34641643

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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Recombinant Human RNASE3 Protein, N-His-SUMO [YHC94602]
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