Catalog No.
YHD46201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys2-Gln116
Predicted molecular weight
41.19 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P21554
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CNR1, CB1, CANN6, CB-R, CNR, Cannabinoid receptor 1
PAX3-FOXO1 induces cannabinoid receptor 1 to enhance cell invasion and metastasis. PMID: 22037868
Changes in the expression levels of CB1 and GLP-1R mRNAs and microRNAs 33a and 122 in the liver of type 2 diabetic rats treated with ghrelin. PMID: 31468622
Effects of omega-3 supplementation on components of the endocannabinoid system and metabolic and inflammatory responses in adipose and liver of peripartum dairy cows. PMID: 36183098
Measles virus N protein inhibits host translation by binding to eIF3-p40. PMID: 17686838
In vitro reconstitution of antimicrobial pathogen activity by expressed recombinant bovine lactoferrin N-terminal peptide in Escherichia coli. PMID: 17466115
SARS coronavirus nucleocapsid immunodominant T-cell epitope cluster is common to both exogenous recombinant and endogenous DNA-encoded immunogens. PMID: 16387339
Quantitative image cytometry of hepatocytes expressing gamma-glutamyl transpeptidase and glutathione S-transferase in diethylnitrosamine-initiated rats treated with phenobarbital and/or phthalate esters. PMID: 1352315
In-silico analysis of recombinant protein vaccines based on the spike protein of Indonesian SARS-CoV-2 through a reverse vaccinology approach. PMID: 35250426
Detection of severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in human serum using a localized surface plasmon coupled fluorescence fiber-optic biosensor. PMID: 19660929
Wheat germ cell-free expression system for protein production. PMID: 18429309
Trimodal GSTT1 and GSTM1 genotyping assay by real-time PCR. PMID: 16011037
[Preparation and identification of a monoclonal antibody against recombinant human L-type pyruvate kinase N]. PMID: 20848771
Modulation of ageing mice microglia functions during neuroinflammation using synthetic cannabinoids., PMID:40320115
Identification and verification of international neuroblastoma staging system (INSS) stage-related genes as potential biomarkers for neuroblastoma prognostic models., PMID:40302936
Identifying therapeutic target genes for diabetic retinopathy using systematic druggable genome-wide Mendelian randomization., PMID:40301928
Probiotic Bactolac alleviates depression-like behaviors by modulating BDNF, NLRP3 and MC4R levels, reducing neuroinflammation and promoting neural repair in rat model., PMID:40281288
Characterizing the Role of Endocannabinoid Receptor Cnr1 in Mouse Ovarian Granulosa Cells., PMID:40119741
CB1 and CB2 receptors differentially modulate the cognitive impact of maternal immune activation and perinatal cannabinoid exposure., PMID:40113177
CB1 cannabinoid receptor agonists induce acute respiratory depression in awake mice., PMID:40064359
Spinal dorsal horn neurons involved in the alleviating effects of cannabinoid receptor agonists on neuropathic allodynia-like behaviors in rats., PMID:40058945
Astrocytic cannabinoid receptor 1 promotes resilience by dampening stress-induced blood-brain barrier alterations., PMID:40016352
Knockdown of the type 1 cannabinoid receptor in the central amygdala increases both spontaneous and water deprivation-induced sodium intake in rats., PMID:39965157
Promising Antidepressant Potential: The Role of Lactobacillus rhamnosus GG in Mental Health and Stress Response., PMID:39962033
The Presence of the Endocannabinoid System in an In Vitro Model of Gorham-Stout Disease and Its Possible Role in the Pathogenesis., PMID:39940911
The endocannabinoid system's genetic polymorphisms in sickle cell anemia patients., PMID:39738165
GENETIC VARIANTS IN ANTIPSYCHOTIC METABOLISM: POLYMORPHISM PROFILES IN KAZAKH COHORT WITH PARANOID SCHIZOPHRENIA., PMID:39724888
Cannabis sativa alleviates experimentally acetic acid- induced ulcerative colitis in rats: targeting CB1/SIRT/MAPK signaling pathways., PMID:39721800
Cannabidiol induces autophagy via CB1 receptor and reduces α-synuclein cytosolic levels., PMID:39710053
Growth hormone secretagogue receptor and cannabinoid receptor type 1 intersection in the mouse brain., PMID:39702649
CB1R activates the epilepsy-associated protein Go to regulate neurotransmitter release and synaptic plasticity in the cerebellum., PMID:39602265
Impacts of maternal separation stress on ethanol intake and endocannabinoid system in adolescent mice., PMID:39579855
Temporal and spatial layout of endocannabinoid system components in the mouse suprachiasmatic nucleus., PMID:39571963
Nerve injury inhibits Oprd1 and Cnr1 transcription through REST in primary sensory neurons., PMID:39496614
Selective blockade of cannabinoid receptors influences motoneuron survival and glial responses after neonatal axotomy., PMID:39481830
The endocannabinoid system in bovine tissues: characterization of transcript abundance in the growing Holstein steer., PMID:39438841
Exploring the material basis and molecular targets of Changma Xifeng tablet in treating Tourette syndrome: an integrative approach of network pharmacology and miRNA analysis., PMID:39436634
Pharmacological inhibition of the CB1 cannabinoid receptor restores abnormal brain mitochondrial CB1 receptor expression and rescues bioenergetic and cognitive defects in a female mouse model of Rett syndrome., PMID:39300547
Investigating the Role of Cannabinoid Type 1 Receptors in Vascular Function and Remodeling in a Hypercholesterolemic Mouse Model with Low-Density Lipoprotein-Cannabinoid Type 1 Receptor Double Knockout Animals., PMID:39273484
Alcohol activates cannabinoid receptor 1 and 2 in a model of pathogen induced pulmonary inflammation., PMID:39251147
CB1 Promotes Osteogenic Differentiation Potential of Periodontal Ligament Stem Cells by Enhancing Mitochondrial Transfer of Bone Marrow Mesenchymal Stem Cells., PMID:39221983
Anti-inflammatory effects of phytocannabinoids and terpenes on inflamed Tregs and Th17 cells in vitro., PMID:39208564
Region-Specific Gene Expression Changes Associated with Oleoylethanolamide-Induced Attenuation of Alcohol Self-Administration., PMID:39201687
DNA methylation at cannabinoid type 1 and dopamine D2 receptor genes in saliva samples of psychotic subjects: Is there an effect of Cannabis use?, PMID:39127265
Endocannabinoids and their receptors modulate endometriosis pathogenesis and immune response., PMID:39120997
Assessment of the molecular mechanism in fish using eugenol as anesthesia based on network pharmacology., PMID:39042183
Cytological and Transcriptome Analyses Provide Insights into Persimmon Fruit Size Formation (Diospyros kaki Thunb.)., PMID:39000347
Genetic Evidence of Endocannabinoid System on Perceived Stress and Restricted Food Intake: The Role of Variants rs324420 in FAAH Gene and rs1049353 in CNR1 Gene., PMID:38968406
Characterization of the effects of cannabinoid receptor deletion on energy metabolism in female C57BL mice., PMID:38962676
Additive antinociceptive action of intrathecal anandamide reuptake inhibitor and morphine in the management of post-incisional pain in rats., PMID:38943991
Cannabinoid receptor 1 positive allosteric modulator ZCZ011 shows differential effects on behavior and the endocannabinoid system in HIV-1 Tat transgenic female and male mice., PMID:38913661
Transcriptome Study of rd1Mouse Brain and Association with Parkinson's Disease., PMID:38911794
Pharmaceutical targeting of the cannabinoid type 1 receptor impacts the crosstalk between immune cells and islets to reduce insulitis in humans., PMID:38864887
SGIP1 binding to the α-helical H9 domain of cannabinoid receptor 1 promotes axonal surface expression., PMID:38864427
GPCR Function in Autophagy Control: A Systematic Approach of Chemical Intervention., PMID:38848865
Myeloid cannabinoid CB1 receptor deletion confers atheroprotection in male mice by reducing macrophage proliferation in a sex-dependent manner., PMID:38838211
Gut Microbiota-Mediated Alterations of Hippocampal CB1R Regulating the Diurnal Variation of Cognitive Impairment Induced by Hepatic Ischemia-Reperfusion Injury in Mice., PMID:38824460
Peripherally restricted cannabinoid and mu-opioid receptor agonists synergistically attenuate neuropathic mechanical hypersensitivity in mice., PMID:38815196
Correlations of the CNR1 Gene with Personality Traits in Women with Alcohol Use Disorder., PMID:38791212
Maternal supplementation with n-3 fatty acids affects placental lipid metabolism, inflammation, oxidative stress, the endocannabinoid system, and the neonate cytokine concentrations in dairy cows., PMID:38769527
Cannabinoid receptors as new targets for HTLV-1 associated myelopathy (HAM/TSP) treatment., PMID:38704874
Cannabidiol attenuates seizure susceptibility and behavioural deficits in adult CDKL5R59X knock-in mice., PMID:38654472
Cannabinoid receptor type 1 activation causes a water diuresis by inducing an acute central diabetes insipidus in mice., PMID:38634131
For research use only. Not for human or drug use.
