Endoplasmic Reticulum Stress and Unfolded Protein Response in Neurodegenerative Diseases. PMID: 32854418
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. PMID: 11779464
Roles for ATF6 and the sarco/endoplasmic reticulum protein quality control system in the heart. PMID: 24140798
ATF6 aggravates acinar cell apoptosis and injury by regulating p53/AIFM2 transcription in Severe Acute Pancreatitis. PMID: 32724472
ATF6 Decreases Myocardial Ischemia/Reperfusion Damage and Links ER Stress and Oxidative Stress Signaling Pathways in the Heart. PMID: 27932512
ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells. PMID: 30241539
ATF6 Regulates Cardiac Hypertrophy by Transcriptional Induction of the mTORC1 Activator, Rheb. PMID: 30582446
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. PMID: 11163209
Mfn2 modulates the UPR and mitochondrial function via repression of PERK. PMID: 23921556
Alterations of EDEM1 functions enhance ATF6 pro-survival signaling. PMID: 30281916
Activating Transcription Factor 6 Mediates Inflammatory Signals in Intestinal Epithelial Cells Upon Endoplasmic Reticulum Stress. PMID: 32673694
The Ca2+ -binding protein sorcin stimulates transcriptional activity of the unfolded protein response mediator ATF6. PMID: 33960419
Gremlin-1 Promotes Colorectal Cancer Cell Metastasis by Activating ATF6 and Inhibiting ATF4 Pathways. PMID: 35883579
Going for the Golgi: small PDI protein helps ATF6 perform better under stress. PMID: 31328793
Ubiquitination of ATF6 by disease-associated RNF186 promotes the innate receptor-induced unfolded protein response. PMID: 34623328
Activation of the ATF6 branch of the unfolded protein response in neurons improves stroke outcome. PMID: 27217380
SUMOylation represses the transcriptional activity of the Unfolded Protein Response transducer ATF6. PMID: 29061306
Avian reovirus infection activate the cellular unfold protein response and induced apoptosis via ATF6-dependent mechanism. PMID: 33741393
The Epstein-Barr Virus Lytic Protein BMLF1 Induces Upregulation of GRP78 Expression through ATF6 Activation. PMID: 33919712
The 8ab protein of SARS-CoV is a luminal ER membrane-associated protein and induces the activation of ATF6. PMID: 19304306
ATF6 Activation Reduces Amyloidogenic Transthyretin Secretion through Increased Interactions with Endoplasmic Reticulum Proteostasis Factors. PMID: 35626697
ATF6 deficiency damages the development of spermatogenesis in male Atf6 knockout mice. PMID: 34904262
Quantitative Interactome Proteomics Reveals a Molecular Basis for ATF6-Dependent Regulation of a Destabilized Amyloidogenic Protein. PMID: 31105062
Non-Structural Protein 2B of Human Rhinovirus 16 Activates Both PERK and ATF6 Rather Than IRE1 to Trigger ER Stress. PMID: 30717233
Endoplasmic reticulum-stress and unfolded protein response-activation in immune-mediated necrotizing myopathy. PMID: 35703068
BMP2 protein regulates osteocalcin expression via Runx2-mediated Atf6 gene transcription. PMID: 22102412
SIRT1 protects the heart from ER stress-induced cell death through eIF2α deacetylation. PMID: 27911441
Designing Novel Therapies to Mend Broken Hearts: ATF6 and Cardiac Proteostasis. PMID: 32138230
Lipid-dependent regulation of the unfolded protein response. PMID: 25543896
Transcriptional factor ATF6 is involved in odontoblastic differentiation. PMID: 24570149
The unfolded protein response transducer ATF6 represents a novel transmembrane-type endoplasmic reticulum-associated degradation substrate requiring both mannose trimming and SEL1L protein. PMID: 24043630
Evolutionary Aspects of the Unfolded Protein Response. PMID: 35940910
Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress. PMID: 29851562
A review of the mammalian unfolded protein response. PMID: 21809331
Activating transcription factor-6 (ATF6) mediates apoptosis with reduction of myeloid cell leukemia sequence 1 (Mcl-1) protein via induction of WW domain binding protein 1. PMID: 21841196
Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation. PMID: 17686766
Divest yourself of a preconceived idea: transcription factor ATF6 is not a soluble protein! PMID: 20219975
A novel role of ER stress signal transducer ATF6 in regulating enterovirus A71 viral protein stability. PMID: 29386036
Molecular signal networks and regulating mechanisms of the unfolded protein response. PMID: 28070992
Trichostatin A increases BDNF protein expression by improving XBP-1s/ATF6/GRP78 axis in Schwann cells of diabetic peripheral neuropathy. PMID: 33378965
Peste des Petits Ruminants Virus Upregulates STING to Activate ATF6-Mediated Autophagy. PMID: 36197111
Unfolding the unfolded protein response: unique insights into brain ischemia. PMID: 25830481
Endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) in plants. PMID: 26060134
Profile of the unfolded protein response in rat cerebellar cortical development. PMID: 31132146
Identification and functional characterization of unfolded protein response transcription factor ATF6 gene in kuruma shrimp Marsupenaeus japonicus. PMID: 29427718
The unfolded protein response and Alzheimer's disease. PMID: 11406343
Underglycosylation of ATF6 as a novel sensing mechanism for activation of the unfolded protein response. PMID: 14699159
Modulation of Unfolded Protein Response by Methylmercury. PMID: 28867746
ATF6 modulates SREBP2-mediated lipogenesis. PMID: 14765107
The unfolded protein response. PMID: 12692187
Unfolded protein response activation in cataracts. PMID: 25263040
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. PMID: 10564271
LncRNA H19 inhibits ER stress induced apoptosis and improves diabetic cardiomyopathy by regulating PI3K/AKT/mTOR axis. PMID: 36044268
Hepatitis C virus core protein activates autophagy through EIF2AK3 and ATF6 UPR pathway-mediated MAP1LC3B and ATG12 expression. PMID: 24589849
Coordination of ATF6-mediated transcription and ATF6 degradation by a domain that is shared with the viral transcription factor, VP16. PMID: 11909875
[Unfolded protein response: its role in physiology and physiopathology]. PMID: 17349291
Targeting the IRE1α/XBP1 and ATF6 arms of the unfolded protein response enhances VEGF blockade to prevent retinal and choroidal neovascularization. PMID: 23395094
Endoplasmic reticulum stress sensing in the unfolded protein response. PMID: 23388626
PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response. PMID: 26674075
Role of the unfolded protein response in cell death. PMID: 16374548
The role of ORMDL3/ATF6 in compensated beta cell proliferation during early diabetes. PMID: 31061237
Expressions of ATF6, XBP1, and GRP78 in normal tissue, atypical adenomatous hyperplasia, and adenocarcinoma of the lung. PMID: 30121368
Redox signaling loops in the unfolded protein response. PMID: 22481091
Hepatitis B virus X protein (HBx) activates ATF6 and IRE1-XBP1 pathways of unfolded protein response. PMID: 17092596
Explore on the effect of ATF6 on cell growth and apoptosis in cartilage development. PMID: 24934104
Transcriptional induction of the human asparagine synthetase gene during the unfolded protein response does not require the ATF6 and IRE1/XBP1 arms of the pathway. PMID: 18840095
Modulation of the unfolded protein response by GRP78 in prostate cancer. PMID: 21266234
The UPR Activator ATF6 Responds to Proteotoxic and Lipotoxic Stress by Distinct Mechanisms. PMID: 30086303
Selective activation of the transcription factor ATF6 mediates endoplasmic reticulum proliferation triggered by a membrane protein. PMID: 21521793
ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1. PMID: 10866666
The effects of IRE1, ATF6, and PERK signaling on adRP-linked rhodopsins. PMID: 24664756
Physiological unfolded protein response regulated by OASIS family members, transmembrane bZIP transcription factors. PMID: 21438114
Selective activation of ATF6 and PERK endoplasmic reticulum stress signaling pathways prevent mutant rhodopsin accumulation. PMID: 22956602
Luminal domain of ATF6 alone is sufficient for sensing endoplasmic reticulum stress and subsequent transport to the Golgi apparatus. PMID: 21150130
Proteome and Glycoproteome Analyses Reveal the Protein N-Linked Glycosylation Specificity of STT3A and STT3B. PMID: 36139350
Sensing endoplasmic reticulum stress. PMID: 22399379
The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress. PMID: 22268789
Stress-sensing mechanisms in the unfolded protein response: similarities and differences between yeast and mammals. PMID: 19942680
Differences in Unfolded Protein Response Pathway Activation in the Lenses of Three Types of Cataracts. PMID: 26091066
Activation of the Akt-NF-kappaB pathway by subtilase cytotoxin through the ATF6 branch of the unfolded protein response. PMID: 19561103
High-content screening identifies inhibitors of the nuclear translocation of ATF6. PMID: 26707144
Cerebral ischemia and the unfolded protein response. PMID: 15379881
Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs. PMID: 34186245
Lipid bilayer stress and proteotoxic stress-induced unfolded protein response deploy divergent transcriptional and non-transcriptional programmes. PMID: 31028913
In vitro reconstitution of ER-stress induced ATF6 transport in COPII vesicles. PMID: 19822759
BiP binding keeps ATF6 at bay. PMID: 12110159
ATF6 activation reduces the secretion and extracellular aggregation of destabilized variants of an amyloidogenic protein. PMID: 25444553
Activated ATF6 Induces Intestinal Dysbiosis and Innate Immune Response to Promote Colorectal Tumorigenesis. PMID: 30063920
Quantitative Proteomic Analysis Reveals Unfolded-Protein Response Involved in Severe Fever with Thrombocytopenia Syndrome Virus Infection. PMID: 30842332
Roles of Grp78 in Female Mammalian Reproduction. PMID: 28389754
The UPR signaling molecule ATF6 is a poor prognostic marker in gastric cancer. PMID: 35835674
[Pathogenic Mechanism of Diabetes Development Due to Dysfunction of Unfolded Protein Response]. PMID: 27252061
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. PMID: 11850408
Downregulation of RIP3 Improves the Protective Effect of ATF6 in an Acute Liver Injury Model. PMID: 34778458
The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels. PMID: 19667116
Gene regulatory network of unfolded protein response genes in endoplasmic reticulum stress. PMID: 22802018
Arsenic trioxide induces unfolded protein response in vascular endothelial cells. PMID: 23892647
Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response. PMID: 12014989
The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout. PMID: 25009220
Repression of viral gene expression and replication by the unfolded protein response effector XBP1u. PMID: 32065579
Apelin-13 Alleviates Early Brain Injury after Subarachnoid Hemorrhage via Suppression of Endoplasmic Reticulum Stress-mediated Apoptosis and Blood-Brain Barrier Disruption: Possible Involvement of ATF6/CHOP Pathway. PMID: 30036660
[Regulation of osteogenesis and chondrogenesis by unfolded protein respone]. PMID: 22416468
Quinocetone triggered ER stress-induced autophagy via ATF6/DAPK1-modulated mAtg9a trafficking. PMID: 27085326
ATF6 upregulates XBP1S and inhibits ER stress-mediated apoptosis in osteoarthritis cartilage. PMID: 24269637
Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response. PMID: 10856300
Activation of the Unfolded Protein Response in Sporadic Inclusion-Body Myositis but Not in Hereditary GNE Inclusion-Body Myopathy. PMID: 25978849
An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1. PMID: 30504459
Interaction of ATF6 and serum response factor. PMID: 9271374
Activation of the unfolded protein response in human acute myeloid leukemia. PMID: 21266233
ER stress-related ATF6 upregulates CIP2A and contributes to poor prognosis of colon cancer. PMID: 30063110
Grass carp (Ctenopharyngodon idella) ATF6 (activating transcription factor 6) modulates the transcriptional level of GRP78 and GRP94 in CIK cells. PMID: 26988288
An IFN-γ-stimulated ATF6-C/EBP-β-signaling pathway critical for the expression of Death Associated Protein Kinase 1 and induction of autophagy. PMID: 22699507
Activation of the unfolded protein response by Listeria monocytogenes. PMID: 22321539
Endoplasmic Reticulum-Associated Biomarkers for Molecular Phenotyping of Rare Kidney Disease. PMID: 33671535
Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response. PMID: 11256944
Regulation of microRNA expression in the heart by the ATF6 branch of the ER stress response. PMID: 22326432
Hepatitis C virus NS2 protein triggers endoplasmic reticulum stress and suppresses its own viral replication. PMID: 20801537
p38 Mitogen-activated protein kinase mediates the transcriptional induction of the atrial natriuretic factor gene through a serum response element. A potential role for the transcription factor ATF6. PMID: 9685422
Transmembrane bZIP transcription factors in ER stress signaling and the unfolded protein response. PMID: 17887918
High expression of active ATF6 aggravates endoplasmic reticulum stress‑induced vascular endothelial cell apoptosis through the mitochondrial apoptotic pathway. PMID: 29512699
[Activating transcription factor 6-C/EBP homologous protein pathway mediates advanced glycated albumin-induced macrophage apoptosis]. PMID: 29270592
The endoplasmic reticulum stress response: A link with tuberculosis? PMID: 26980496
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