Please ensure Javascript is enabled for purposes of website accessibility
Home / Products / Recombinant Protein / Other Proteins

Recombinant Human FOXA3 Protein, N-His-SUMO

Catalog #:   YHF12602 Specific References (107) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P55318
Protein length: Ser121-Glu202
Overview

Catalog No.

YHF12602

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Ser121-Glu202

Predicted molecular weight

21.95 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P55318

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

TCF-3G, TCF3G, Fork head-related protein FKH H3, HNF-3-gamma, HNF-3G, HNF3G, FOXA3, Hepatocyte nuclear factor 3-gamma, Forkhead box protein A3, Transcription factor 3G

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Human FOXA3 protein
References

FOXA3 induction under endoplasmic reticulum stress contributes to non-alcoholic fatty liver disease. PMID: 33548387

Genomic analyses identify molecular subtypes of pancreatic cancer. PMID: 26909576

Human FOX gene family (Review). PMID: 15492844

Hypoxia-induced LncRNA DACT3-AS1 upregulates PKM2 to promote metastasis in hepatocellular carcinoma through the HDAC2/FOXA3 pathway. PMID: 35764883

FOXA3 Is Expressed in Multiple Cell Lineages in the Mouse Testis and Regulates Pdgfra Expression in Leydig Cells. PMID: 28379539

Foxa3 induces goblet cell metaplasia and inhibits innate antiviral immunity. PMID: 24392884

Transcription factor FOXA3 promotes the development of Hepatoblastoma via regulating HNF1A, AFP, and ZFHX3 expression. PMID: 33368532

PAR2 promotes impaired glucose uptake and insulin resistance in NAFLD through GLUT2 and Akt interference. PMID: 35603482

Reprogramming the spleen into a functioning 'liver' in vivo. PMID: 34996824

FOXA3, a Negative Regulator of Nur77 Expression and Activity in Testicular Steroidogenesis. PMID: 33763129

Direct reprogramming of human fibroblasts to functional and expandable hepatocytes. PMID: 24582927

Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines. PMID: 32170132

Opposing Roles of FoxA1 and FoxA3 in Intrahepatic Cholangiocarcinoma Progression. PMID: 32151057

m6A RNA methylation-mediated HNF3γ reduction renders hepatocellular carcinoma dedifferentiation and sorafenib resistance. PMID: 33361765

Impact of Fetal Exposure to Endocrine Disrupting Chemical Mixtures on FOXA3 Gene and Protein Expression in Adult Rat Testes. PMID: 36674726

Hepatic Forkhead Box Protein A3 Regulates ApoA-I (Apolipoprotein A-I) Expression, Cholesterol Efflux, and Atherogenesis. PMID: 31291759

Distinct roles of FOXA2 and FOXA3 in allergic airway disease and asthma. PMID: 19628779

Glucose restriction delays senescence and promotes proliferation of HUVECs via the AMPK/SIRT1-FOXA3-Beclin1 pathway. PMID: 32768436

Role of forkhead box protein A3 in age-associated metabolic decline. PMID: 25225406

Forkhead box A3 mediates glucocorticoid receptor function in adipose tissue. PMID: 26957608

Regulation of testicular steroidogenesis by Foxa3 via transcriptional modulation of ERα signaling in type 2 diabetes mellitus (T2DM). PMID: 28645613

Foxa3 (HNF-3gamma) binds to and activates the rat proglucagon gene promoter but is not essential for proglucagon gene expression. PMID: 12000309

Calorie hoarding and thrifting: Foxa3 finds a way. PMID: 26451291

Foxa3 (hepatocyte nuclear factor 3gamma ) is required for the regulation of hepatic GLUT2 expression and the maintenance of glucose homeostasis during a prolonged fast. PMID: 11546810

Impaired male fertility and atrophy of seminiferous tubules caused by haploinsufficiency for Foxa3. PMID: 17488644

FOXA3 Polymorphisms Are Associated with Metabolic Parameters in Individuals with Subclinical Atherosclerosis and Healthy Controls-The GEA Mexican Study. PMID: 35625529

Analysis of variants and mutations in the human winged helix FOXA3 gene and associations with metabolic traits. PMID: 25672906

Winged helix proteins. PMID: 10679470

Forced expression of Hnf1b/Foxa3 promotes hepatic fate of embryonic stem cells. PMID: 27107701

A genetic screen reveals Foxa3 and TNFR1 as key regulators of liver repopulation. PMID: 25934503

Protein or amino acid deprivation differentially regulates the hepatic forkhead box protein A (FOXA) genes through an activating transcription factor-4-independent pathway. PMID: 19415718

Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq. PMID: 19919681

The winged helix transcription factor Foxa3 regulates adipocyte differentiation and depot-selective fat tissue expansion. PMID: 23798556

Conversion of Fibroblasts to Hepatocytes In Vitro. PMID: 30536093

FoxA3 and goosecoid promote anterior neural fate through inhibition of Wnt8a activity before the onset of gastrulation. PMID: 16364286

Whole-exome sequencing identifies FOXL2, FOXA2 and FOXA3 as candidate genes for monogenic congenital anomalies of the kidneys and urinary tract. PMID: 34473308

Transcriptional activators in hepatocytes. PMID: 2078499

Direct conversion of human fibroblasts into hepatocyte-like cells by ATF5, PROX1, FOXA2, FOXA3, and HNF4A transduction. PMID: 29192290

Induction of Functional Hepatocyte-Like Cells by Overexpression of FOXA3 and HNF4α in Rat Bone Marrow Mesenchymal Stem Cells. PMID: 25896100

Autophagy and protein turnover signaling in slow-twitch muscle during exercise. PMID: 24389528

Inhibition of the liver enriched protein FOXA2 recovers HNF6 activity in human colon carcinoma and liver hepatoma cells. PMID: 20967225

Winged-helix transcription factors and pancreatic development. PMID: 15631623

Conversion of Fibroblasts to Hepatocyte-Like Cells In Vivo. PMID: 30536094

The Dynamics of Transcriptional Activation by Hepatic Reprogramming Factors. PMID: 32755593

Genetic resistance to DEHP-induced transgenerational endocrine disruption. PMID: 31181066

Persistence of LPS-induced lung inflammation in surfactant protein-C-deficient mice. PMID: 23795648

Forkhead box A3 attenuated the progression of fibrosis in a rat model of biliary atresia. PMID: 28358366

Generation of functional hepatocytes by forward programming with nuclear receptors. PMID: 35959725

The Foxa family of transcription factors in development and metabolism. PMID: 16909212

Negative regulation of hepatitis B virus replication by forkhead box protein A in human hepatoma cells. PMID: 25836733

Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology. PMID: 35347136

Conversion of hepatoma cells to hepatocyte-like cells by defined hepatocyte nuclear factors. PMID: 30560924

Toxic effects of isofenphos-methyl on zebrafish embryonic development. PMID: 36871354

Immature rat testis sustained long-term development using an integrative model. PMID: 36195947

Nonintegrating Direct Conversion Using mRNA into Hepatocyte-Like Cells. PMID: 30327781

The hepatocyte nuclear factor-3/forkhead transcription regulatory family in development, inflammation, and neoplasia. PMID: 7576194

Direct Conversion of Mouse Fibroblasts into Cholangiocyte Progenitor Cells. PMID: 29606616

Transcriptional regulation of neuronal genes and its effect on neural functions: NAD-dependent histone deacetylase SIRT1 (Sir2alpha). PMID: 16006743

Somatic MIWI2 Hinders Direct Lineage Reprogramming From Fibroblast to Hepatocyte. PMID: 30805989

Converting intestine into esophagus: anterior-posterior patterning of the vertebrate gut requires Cdx2. PMID: 20107317

Lineage conversion of mouse fibroblasts to pancreatic α-cells. PMID: 28665920

Hepatoprotective effect of Qushihuayu formula on non-alcoholic steatohepatitis induced by MCD diet in rat. PMID: 33726778

Collapse of the hepatic gene regulatory network in the absence of FoxA factors. PMID: 32561546

Hepatocytic transcriptional signatures predict comparative drug interaction potential of rifamycin antibiotics. PMID: 32724080

DNMT1/PKR double knockdowned HepG2 (HepG2-DP) cells have high hepatic function and differentiation ability. PMID: 36476676

Evaluation of Innate Immune Mediators Related to Respiratory Viruses in the Lung of Stable COPD Patients. PMID: 32531971

Functional screen identifies regulators of murine hematopoietic stem cell repopulation. PMID: 26880577

Simple Maturation of Direct-Converted Hepatocytes Derived from Fibroblasts. PMID: 30603511

miR-221 confers lapatinib resistance by negatively regulating p27kip1 in HER2-positive breast cancer. PMID: 34382727

Neutrophil Elastase and Interleukin 17 Expressed in the Pig Colon during Brachyspira hyodysenteriae Infection Synergistically with the Pathogen Induce Increased Mucus Transport Speed and Production via Mitogen-Activated Protein Kinase 3. PMID: 28559407

Three-Dimensional Bioprinting of Hepatic Structures with Directly Converted Hepatocyte-Like Cells. PMID: 28726547

Iristectorigenin A exerts novel protective properties against airway inflammation and mucus hypersecretion in OVA-induced asthmatic mice: Iristectorigenin A ameliorates asthma phenotype. PMID: 35752075

Generation of integration-free induced hepatocyte-like cells from mouse fibroblasts. PMID: 26503743

Transcription Factors and Medium Suitable for Initiating the Differentiation of Human-Induced Pluripotent Stem Cells to the Hepatocyte Lineage. PMID: 26773721

[Identification of master regulators for induction of hepatocyte differentiation]. PMID: 23012878

Liver-enriched transcription factors and hepatocyte differentiation. PMID: 8641560

Direct conversion of human fibroblast to hepatocytes using a single inducible polycistronic vector. PMID: 31685034

Enhanced direct conversion of fibroblasts into hepatocyte-like cells by Kdm2b. PMID: 27103435

Expansion of Transdifferentiated Human Hepatocytes in a Serum-Free Microcarrier Culture System. PMID: 31722057

Direct Conversion of Human Endothelial Cells Into Liver Cancer-Forming Cells Using Nonintegrative Episomal Vectors. PMID: 35220676

Direct reprogramming of human umbilical vein- and peripheral blood-derived endothelial cells into hepatic progenitor cells. PMID: 33087715

Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells. PMID: 27776277

Tissue adaptation of regulatory and intraepithelial CD4⁺ T cells controls gut inflammation. PMID: 27256884

NOTCH3 contributes to rhinovirus-induced goblet cell hyperplasia in COPD airway epithelial cells. PMID: 29991510

Preferential Generation of 15-HETE-PE Induced by IL-13 Regulates Goblet Cell Differentiation in Human Airway Epithelial Cells. PMID: 28723225

Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes In Vivo Attenuates Liver Fibrosis. PMID: 26923201

Tiotropium attenuates IL-13-induced goblet cell metaplasia of human airway epithelial cells. PMID: 25995156

Generation of Mouse and Human Organoid-Forming Intestinal Progenitor Cells by Direct Lineage Reprogramming. PMID: 28943029

Baf60b-mediated ATM-p53 activation blocks cell identity conversion by sensing chromatin opening. PMID: 28303890

Krüppel-like factor 9 promotes hepatic cytochrome P450 2D6 expression during pregnancy in CYP2D6-humanized mice. PMID: 25217496

Notch2 is required for inflammatory cytokine-driven goblet cell metaplasia in the lung. PMID: 25558064

3D scaffold-free microlivers with drug metabolic function generated by lineage-reprogrammed hepatocytes from human fibroblasts. PMID: 33461059

Chemical cocktails enable hepatic reprogramming of human urine-derived cells with a single transcription factor. PMID: 30315254

Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site. PMID: 28644006

Expression and prognosis analyses of forkhead box A (FOXA) family in human lung cancer. PMID: 30415009

A Multiple-Cell Microenvironment in a 3-Dimensional System Enhances Direct Cellular Reprogramming Into Hepatic Organoids. PMID: 30401413

Bee Venom Phospholipase A2 Induces Regulatory T Cell Populations by Suppressing Apoptotic Signaling Pathway. PMID: 32235689

Hepatocyte nuclear factor-3 (HNF-3) binds to the insulin response sequence in the IGF binding protein-1 (IGFBP-1) promoter and enhances promoter function. PMID: 7524494

Chemical Cocktails Enable Hepatic Reprogramming of Mouse Fibroblasts with a Single Transcription Factor. PMID: 28757167

Temporal and spatial expression of the Fox gene family in the Leech Helobdella austinensis. PMID: 30280505

Zymolytic grain extract facilitates the conversion of liver tumor cells to hepatocyte-like cells through hepatocyte nuclear factors. PMID: 36436492

Novel insights into Dhh signaling in antler chondrocyte proliferation and differentiation: Involvement of Foxa. PMID: 31960430

Pbx1 is essential for growth of zebrafish swim bladder. PMID: 20108353

Cloning of an Atlantic salmon transcription factor. PMID: 8674586

PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. PMID: 17476212

Reprogramming fibroblasts into bipotential hepatic stem cells by defined factors. PMID: 23871605

Transcriptomic characterization of hepatocellular carcinoma with CTNNB1 mutation. PMID: 24798046

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

Need help with your order?

Find out more about placing an order here

Recombinant Human FOXA3 Protein, N-His-SUMO [YHF12602]
Terms of sale Website terms of use Cookie policy Privacy
Copyright © 2025 AntibodySystem SAS. All Rights Reserved.            All Products are for Research Use Only