Catalog No.
YHC86903
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly131-Ile248
Predicted molecular weight
25.30 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P11226
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
COLEC1, Mannose-binding protein C, MBL2, Mannan-binding protein, MBP1, Mannose-binding lectin, MBL, Collectin-1, MBP-C
Mannose-Binding Lectin 2 (MBL2) combined genotypes deficiency is associated with susceptibility for Oral Lichen Planus. PMID: 30794720
Lectin-carbohydrate interactions: fine specificity difference between two mannose-binding proteins. PMID: 10589993
Characterization of two mannose-binding protein cDNAs from rhesus monkey (Macaca mulatta): structure and evolutionary implications. PMID: 8877375
cDNAs and deduced amino acid sequences of subunits in the binding component of mouse bactericidal factor, Ra-reactive factor: similarity to mannose-binding proteins. PMID: 1637828
A Meta-analysis of MBL2 Polymorphisms and Tuberculosis Risk. PMID: 27876780
MBL2, FCN1, FCN2 and FCN3-The genes behind the initiation of the lectin pathway of complement. PMID: 19501910
Association of MBL2 exon1 polymorphisms with high-risk human papillomavirus infection and cervical cancers: a meta-analysis. PMID: 27619685
If there is an evolutionary selection pressure for the high frequency of MBL2 polymorphisms, what is it? PMID: 24255984
Genetic polymorphisms of MBL2 and tuberculosis susceptibility: a meta-analysis of 22 case-control studies. PMID: 30393476
MBL2 gene polymorphisms and its relation to infection in Brazilian systemic lupus erythematosus patients: A 10-years follow-up study. PMID: 35104178
MBL2 gene variants and susceptibility to meningitis in Egyptian patients. PMID: 37121343
Association of MBL2 Exon 1 Polymorphisms With Multibacillary Leprosy. PMID: 33013845
MBL2 polymorphism may be a protective factor of autoimmune thyroid disease susceptibility. PMID: 36318338
MBL2 gene polymorphisms related to HIV-1 infection susceptibility and treatment response. PMID: 36257838
Genetic susceptibility to invasive meningococcal disease: MBL2 structural polymorphisms revisited in a large case-control study and a systematic review. PMID: 22296677
Investigation of MBL2 and NOS3 functional gene variants in suspected COVID-19 PCR (-) patients. PMID: 34570692
Complement protein levels and MBL2 polymorphisms are associated with dengue and disease severity. PMID: 32913345
MBL2 polymorphisms and the risk of asthma: A meta-analysis. PMID: 27590640
MBL2 variations and malaria susceptibility in Indian populations. PMID: 24126531
MBL2 genetic polymorphisms and HIV-1 mother-to-child transmission in Zambia. PMID: 26740328
IFNL4, ACE1, PKR, IFNG, MBL2 genetic polymorphisms and severe COVID-19: A protocol for systematic review and meta-analysis. PMID: 35623072
Influence of MBL2 and NOS3 polymorphisms on spontaneous preterm birth in North East Brazil: genetics and preterm birth. PMID: 29886784
Association of MIF and MBL2 gene polymorphisms with attempted suicide in patients diagnosed with schizophrenia or bipolar disorder. PMID: 32279906
Genetic Variation in the MBL2 Gene Is Associated with Chlamydia trachomatis Infection and Host Humoral Response to Chlamydia trachomatis Infection. PMID: 36012556
Mannose-binding lectin levels and MBL2 gene polymorphisms are associated with dengue infection in Brazilian children at the early ages. PMID: 35150914
MBL2 gene polymorphisms in HHV-8 infection in people living with HIV/AIDS. PMID: 30482213
MBL2 deficiency is associated with higher genomic bacterial loads during meningococcemia in young children. PMID: 24977653
MBL2 rs7095891 G > A polymorphism was associated with an increased risk of tuberculosis in the Chinese Uygur population. PMID: 30515260
MBL2 polymorphisms - manifestations in Bulgarian patients with adult dermatomyositis and systemic lupus erythematosus. PMID: 24103065
MBL2 polymorphisms in women with atypical squamous cells of undetermined significance. PMID: 25693844
MBL2 gene polymorphisms and susceptibility to tuberculosis in a northeastern Brazilian population. PMID: 23524205
MBL2 gene polymorphism rs1800450 and rheumatic fever with and without rheumatic heart disease: an Egyptian pilot study. PMID: 29653582
Association Study of MBL2 Gene Polymorphisms and Risk of Tuberculosis in Southeast of Iran. PMID: 33270011
MBL2 gene variation affecting serum MBL is associated with prosthetic joint infection in Czech patients after total joint arthroplasty. PMID: 22994203
MBL2 and fever during neutropenia in children with acute lymphoblastic leukaemia. PMID: 22050689
Polymorphisms in the MBL2 gene are associated with the plasma levels of MBL and the cytokines IL-6 and TNF-α in severe COVID-19. PMID: 37138871
MBL2 gene polymorphisms are correlated with high-risk human papillomavirus infection but not with human papillomavirus-related cervical cancer. PMID: 19275921
MBL2, MASP2, AMELX, and ENAM gene polymorphisms and dental caries in Polish children. PMID: 22221294
Role of MIF-173G/C and Mbl2 Codon 54A/B Variants in the Risk of Multiple Myeloma: An Association Study. PMID: 32811420
MBL2 and FCN2 gene polymorphisms in a cohort of Italian children with rheumatic fever: A case-control study. PMID: 28576308
Association of MBL2 gene polymorphisms with pulmonary tuberculosis susceptibility: trial sequence meta-analysis as evidence. PMID: 30666135
MBL2 genotypes and their associations with MBL levels and NICU morbidity in a cohort of Greek neonates. PMID: 25879044
Fetal MBL2 haplotypes combined with viral exposure are associated with adverse pregnancy outcomes. PMID: 21171930
MBL2 and hepatitis C virus infection among injection drug users. PMID: 18452612
Association of mannose-binding lectin 2 (MBL2) and suppressor of cytokine signaling-1 (SOCS1) gene variants in children with febrile neutropenia. PMID: 35115241
MBL2 Genetic Variants in HCV Infection Susceptibility, Spontaneous Viral Clearance and Pegylated Interferon Plus Ribavirin Treatment Response. PMID: 27136459
Platelet thrombus formation in eHUS is prevented by anti-MBL2. PMID: 31881024
MBL2 genetic polymorphisms in Italian children with adenotonsillar hypertrophy. PMID: 17482281
MBL2 gene polymorphisms protect against development of thrombocytopenia associated with severe dengue phenotype. PMID: 18361938
Functional Single-Nucleotide Polymorphisms in the MBL2 and TLR3 Genes Influence Disease Severity in Influenza A (H1N1)pdm09 Virus-Infected Patients from Maharashtra, India. PMID: 35196173
MBL2 and MASP2 gene polymorphisms in patients with hepatocellular carcinoma. PMID: 18221301
MBL2 gene polymorphisms increase the risk of adverse neurological outcome in preterm infants: a preliminary prospective study. PMID: 25119337
Does MBL2 codon 54 polymorphism play a role in the pathogenesis of psoriasis? PMID: 23113841
The MBL2 'LYQA secretor' haplotype is an independent predictor of postoperative myocardial infarction in whites undergoing coronary artery bypass graft surgery. PMID: 17846289
Exploring association between MBL2 gene polymorphisms and the occurrence of clinical blackwater fever through a case-control study in Congolese children. PMID: 31941497
The role of MBL2 gene polymorphism in sepsis incidence. PMID: 26823854
MBL2 genetic screening in patients with recurrent vaginal infections. PMID: 18211540
MBL2 polymorphisms screening in a regional Italian CF Center. PMID: 16046196
MBL2 single nucleotide polymorphism diversity among four ethnic groups as revealed by a bead-based liquid array profiling. PMID: 18952132
Identification of genetic polymorphism of the MBL2 gene and its association with clinical mastitis in Murrah buffaloes. PMID: 36823683
Variant MBL2 genotypes producing low mannose-binding lectin may increase risk of Bacillus Calmette-Guerin osteitis in vaccinated newborns. PMID: 23865867
Association of Single-Nucleotide Polymorphisms of the MBL2 with Atopic Dermatitis in Korean Patients. PMID: 28966513
Haplotype specific-sequencing reveals MBL2 association with asymptomatic Plasmodium falciparum infection. PMID: 19432958
Mannose-binding lectin gene (MBL2) polymorphisms related to the mannose-binding lectin low levels are associated to dengue disease severity. PMID: 27180198
MBL2 gene variants coding for mannose-binding lectin deficiency are associated with increased risk of nephritis in Danish patients with systemic lupus erythematosus. PMID: 24850777
Correlation between MBL2/CD14/TNF-α gene polymorphisms and susceptibility to spinal tuberculosis in Chinese population. PMID: 29298876
Apoe, Mbl2, and Psp plasma protein levels correlate with diabetic phenotype in NZO mice--an optimized rapid workflow for SRM-based quantification. PMID: 23350727
MBL2 functional allelic variants and increased risk for the development of atopic dermatitis in Brazilian children. PMID: 18347304
Gene-environment interaction between MBL2 genotype and smoking, and the risk of gram-positive bacteraemia. PMID: 18782274
Functional variations in MBL2 gene are associated with cutaneous leishmaniasis in the Amazonas state of Brazil. PMID: 25764115
The association of HLA-DRB1 alleles and MBL2 gene variant in pediatric acute lymphoblastic leukemia patients. PMID: 37117150
Association of MBL2 Gene Polymorphism with Dental Caries in Saudi Children. PMID: 27894112
MBL2 polymorphism and risk of severe infections in multiple myeloma patients receiving high-dose melphalan and autologous stem cell transplantation. PMID: 16953214
Effects of MBL2 polymorphisms in patients with diisocyanate-induced occupational asthma. PMID: 25857450
Genetic association study between mbl2 and asthma phenotypes in Chinese children. PMID: 17014624
A variant in the promoter of MBL2 is associated with protection against visceral leishmaniasis in Morocco. PMID: 22995279
Association between MBL2 haplotypes and dengue severity in children from Rio de Janeiro, Brazil. PMID: 31141020
Genetic variants of the MBL2 gene are associated with mortality in pneumococcal sepsis. PMID: 22578937
MBL2 variants in relation to common childhood infections and atopy-related phenotypes in a large German birth cohort. PMID: 17651383
Association of MBL2 polymorphism with asthma after bronchiolitis in infancy. PMID: 22512728
Mannose-binding lectin (MBL2) polymorphisms and inflammation in hypertensive patients. PMID: 21895981
A Rare Genetic Defect of MBL2 Increased the Risk for Progression of IgA Nephropathy. PMID: 30967869
[Complement-activating lectin, RaRF]. PMID: 10502947
For research use only. Not for human or drug use.
