Catalog No.
YHE95101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly30-Val165
Predicted molecular weight
28.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P52797
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EPLG3, EPH-related receptor tyrosine kinase ligand 3, EFL2, LERK-3, EFNA3, Ephrin-A3, LERK3, EFL-2, EHK1-L, EHK1 ligand
Ephrin-A3/EphA2 axis regulates cellular metabolic plasticity to enhance cancer stemness in hypoxic hepatocellular carcinoma. PMID: 35227773
Small extracellular vesicles derived from hypoxic mesenchymal stem cells promote vascularized bone regeneration through the miR-210-3p/EFNA3/PI3K pathway. PMID: 35850484
EFNA3 as a predictor of clinical prognosis and immune checkpoint therapy efficacy in patients with lung adenocarcinoma. PMID: 34645436
EFNA3 long noncoding RNAs induced by hypoxia promote metastatic dissemination. PMID: 25023702
The 1q21.3 region driver gene EFNA3 promotes disease progression via inhibition of lung adenocarcinoma cell apoptosis. PMID: 35706812
A novel necroptosis-related gene index for predicting prognosis and a cold tumor immune microenvironment in stomach adenocarcinoma. PMID: 36389725
Deletion of long noncoding RNA EFNA3 aggravates hypoxia-induced injury in PC-12 cells by upregulation of miR-101a. PMID: 30125989
LncRNA LINC01270 aggravates the progression of gastric cancer through modulation of miR-326/EFNA3 axis. PMID: 35345980
MicroRNA-210 promotes proliferation and invasion of peripheral nerve sheath tumor cells targeting EFNA3. PMID: 24512729
The Pan-Cancer Crosstalk Between the EFNA Family and Tumor Microenvironment for Prognosis and Immunotherapy of Gastric Cancer. PMID: 35309935
Dissecting the roles of Ephrin-A3 in malignant peripheral nerve sheath tumor by TALENs. PMID: 25955218
Hsa_circ_0007478 aggravates NLRP3 inflammasome activation and lipid metabolism imbalance in ox-LDL-stimulated macrophage via miR-765/EFNA3 axis. PMID: 36191606
Loss of the Spinocerebellar Ataxia type 3 disease protein ATXN3 alters transcription of multiple signal transduction pathways. PMID: 30231063
MicroRNA-210 promotes sensory axon regeneration of adult mice in vivo and in vitro. PMID: 27102143
OSCC Exosomes Regulate miR-210-3p Targeting EFNA3 to Promote Oral Cancer Angiogenesis through the PI3K/AKT Pathway. PMID: 32695810
Expression Pattern and Prognostic Value of EPHA/EFNA in Breast Cancer by Bioinformatics Analysis: Revealing Its Importance in Chemotherapy. PMID: 33977106
Differentially expressed miRNA-210 during follicular-luteal transition regulates pre-ovulatory granulosa cell function targeting HRas and EFNA3. PMID: 29131373
EGCG ameliorates the hypoxia-induced apoptosis and osteogenic differentiation reduction of mesenchymal stem cells via upregulating miR-210. PMID: 26780211
Expression analysis of the Epha1 receptor tyrosine kinase and its high-affinity ligands Efna1 and Efna3 during early mouse development. PMID: 16466970
MiR-210-3p-EphrinA3-PI3K/AKT axis regulates the progression of oral cancer. PMID: 32180353
Transcriptional Signatures That Define Ulcerative Colitis in Remission. PMID: 32322884
Inverse Expression Levels of EphrinA3 and EphrinA5 Contribute to Dopaminergic Differentiation of Human SH-SY5Y Cells. PMID: 27217159
Specific and shared targets of ephrin A signaling in epidermal keratinocytes. PMID: 21193391
Differential effects of Th1 versus Th2 cytokines in combination with hypoxia on HIFs and angiogenesis in RA. PMID: 22866899
Comparative integromics on Ephrin family. PMID: 16596216
EphA4/ephrinA3 reverse signaling mediated downregulation of glutamate transporter GLAST in Müller cells in an experimental glaucoma model. PMID: 36416239
Multiplexed targeting of miRNA-210 in stem cell-derived extracellular vesicles promotes selective regeneration in ischemic hearts. PMID: 33879860
Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality. PMID: 33893375
EphrinB1 expression is dysregulated and promotes oncogenic signaling in medulloblastoma. PMID: 25258252
Identification of a Tumor Cell Associated Type I IFN Resistance Gene Expression Signature of Human Melanoma, the Components of Which Have a Predictive Potential for Immunotherapy. PMID: 35269844
Immune response profiling identifies autoantibodies specific to Moyamoya patients. PMID: 23518061
miR-210 Enhances the Therapeutic Potential of Bone-Marrow-Derived Circulating Proangiogenic Cells in the Setting of Limb Ischemia. PMID: 29908843
Optimization of miRNA delivery by using a polymeric conjugate based on deoxycholic acid-modified polyethylenimine. PMID: 31085260
Regulation of granulosa cell functions through NRP-1 mediated internalization of follicular fluid non-exosomal miR-210. PMID: 34599690
Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport. PMID: 19734893
Screening and Validation of the Hypoxia-Related Signature of Evaluating Tumor Immune Microenvironment and Predicting Prognosis in Gastric Cancer. PMID: 34249015
Prediction of blood-based biomarkers and subsequent design of bisulfite PCR-LDR-qPCR assay for breast cancer detection. PMID: 32005108
Leptin induces tube formation in first-trimester extravillous trophoblast cells. PMID: 22717511
Gene Expression Profiling of Muscle Stem Cells Identifies Novel Regulators of Postnatal Myogenesis. PMID: 27446912
Induction, modulation and potential targets of miR-210 in pancreatic cancer cells. PMID: 22672828
Molecular profiling of angiogenesis in hypericin mediated photodynamic therapy. PMID: 18549507
MicroRNA-210 as a novel therapy for treatment of ischemic heart disease. PMID: 20837903
Impact of breast cancer surgery on angiogenesis circulating biomarkers: a prospective longitudinal study. PMID: 23981902
Axon growth and guidance genes identify nascent, immature, and mature olfactory sensory neurons. PMID: 20882566
Oxycodone Self-Administration Induces Alterations in Expression of Integrin, Semaphorin and Ephrin Genes in the Mouse Striatum. PMID: 29946272
Expression analysis of angiogenesis-related genes in Bulgarian patients with early-stage non-small cell lung cancer. PMID: 21528670
Targeted Gene Resequencing (Astrochip) to Explore the Tripartite Synapse in Autism-Epilepsy Phenotype with Macrocephaly. PMID: 26537360
Identification of the angiogenic gene signature induced by EGF and hypoxia in colorectal cancer. PMID: 24180698
Nanoceria inhibit expression of genes associated with inflammation and angiogenesis in the retina of Vldlr null mice. PMID: 23978600
Expression profiling of the ephrin (EFN) and Eph receptor (EPH) family of genes in atherosclerosis-related human cells. PMID: 21672356
Detection of cadherin-17 in human colon cancer LIM1215 cell secretome and tumour xenograft-derived interstitial fluid and plasma. PMID: 23557862
Comparative transcriptome analysis of the swimbladder reveals expression signatures in response to low oxygen stress in channel catfish, Ictalurus punctatus. PMID: 29799804
EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties. PMID: 24488013
A novel 1.4 Mb de novo microdeletion of chromosome 1q21.3 in a child with microcephaly, dysmorphic features and mental retardation. PMID: 19772933
In-depth characterization of the secretome of colorectal cancer metastatic cells identifies key proteins in cell adhesion, migration, and invasion. PMID: 23443137
A Multi-Trait Association Analysis of Brain Disorders and Platelet Traits Identifies Novel Susceptibility Loci for Major Depression, Alzheimer's and Parkinson's Disease. PMID: 36672180
For research use only. Not for human or drug use.
