Catalog No.
YHB56301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser361-Ser428
Predicted molecular weight
19.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95196
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CALEB, NGC, Neuroglycan C, Chondroitin sulfate proteoglycan 5, Acidic leucine-rich EGF-like domain-containing brain protein, CSPG5
Retinal pigment epithelium protein of 65 kDA gene-linked retinal degeneration is not modulated by chicken acidic leucine-rich epidermal growth factor-like domain containing brain protein/Neuroglycan C/ chondroitin sulfate proteoglycan 5. PMID: 24265546
The X-linked intellectual disability protein PHF6 associates with the PAF1 complex and regulates neuronal migration in the mammalian brain. PMID: 23791194
Immunogenomic Landscape Analysis of Prognostic Immune-Related Genes in Hepatocellular Carcinoma. PMID: 34745496
Exploration of prognostic index based on immune-related genes in patients with liver hepatocellular carcinoma. PMID: 32579175
Investigation of the effects of downregulation of jumping translocation breakpoint (JTB) protein expression in MCF7 cells for potential use as a biomarker in breast cancer. PMID: 36225631
Comparative mapping of seven genes in mouse, rat and Chinese hamster chromosomes by fluorescence in situ hybridization. PMID: 10965124
Impaired presynaptic function and elimination of synapses at premature stages during postnatal development of the cerebellum in the absence of CALEB (CSPG5/neuroglycan C). PMID: 23889129
Expression and identification of a new splice variant of neuroglycan C, a transmembrane chondroitin sulfate proteoglycan, in the human brain. PMID: 16299773
Identification of a duplication within the GDF9 gene and novel candidate genes for primary ovarian insufficiency (POI) by a customized high-resolution array comparative genomic hybridization platform. PMID: 24939957
Neuroglycan C, a brain-specific part-time proteoglycan, with a particular multidomain structure. PMID: 15467399
Host genetic predictors of the kynurenine pathway of tryptophan catabolism among treated HIV-infected Ugandans. PMID: 27088321
A prognostic model based on seven immune-related genes predicts the overall survival of patients with hepatocellular carcinoma. PMID: 33962640
Genome-wide association study of cognitive function in diverse Hispanics/Latinos: results from the Hispanic Community Health Study/Study of Latinos. PMID: 32699239
Chondroitin sulfate proteoglycan-5 forms perisynaptic matrix assemblies in the adult rat cortex. PMID: 32653642
Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population. PMID: 19367581
Identification of neurite outgrowth-promoting domains of neuroglycan C, a brain-specific chondroitin sulfate proteoglycan, and involvement of phosphatidylinositol 3-kinase and protein kinase C signaling pathways in neuritogenesis. PMID: 16803884
[Development and regeneration of the central nervous system and neural chondroitin sulfate proteoglycans]. PMID: 15552984
[Function of neuroglycan C (NGC), a brain-specific chondroitin sulfate proteoglycan]. PMID: 17511258
Differential neuroglycan C expression during retinal degeneration in Rpe65-/- mice. PMID: 19050768
Neuroglycan C, a brain-specific chondroitin sulfate proteoglycan, interacts with pleiotrophin, a heparin-binding growth factor. PMID: 20369290
Different roles of the small GTPases Rac1, Cdc42, and RhoG in CALEB/NGC-induced dendritic tree complexity. PMID: 27412363
Behavioral abnormalities of fetal growth retardation model rats with reduced amounts of brain proteoglycans. PMID: 19393646
The neural EGF family member CALEB/NGC mediates dendritic tree and spine complexity. PMID: 17431398
Glycosylation site for chondroitin sulfate on the neural part-time proteoglycan, neuroglycan C. PMID: 15331613
Genomic organization and expression pattern of mouse neuroglycan C in the cerebellar development. PMID: 10617623
Ectodomain shedding of neuroglycan C, a brain-specific chondroitin sulfate proteoglycan, by TIMP-2- and TIMP-3-sensitive proteolysis. PMID: 17532789
Changes in the amounts of chondroitin sulfate proteoglycans in rat brain after neonatal hypoxia-ischemia. PMID: 16041802
cDNA and genomic cloning of lacritin, a novel secretion enhancing factor from the human lacrimal gland. PMID: 11419941
Neuroglycan C, a neural tissue-specific transmembrane chondroitin sulfate proteoglycan, in retinal neural network formation. PMID: 11095636
Phosphorylation of neuroglycan C, a brain-specific transmembrane chondroitin sulfate proteoglycan, and its localization in the lipid rafts. PMID: 11929867
Repeated cocaine administration alters the expression of genes in corticolimbic circuitry after a 3-week withdrawal: a DNA macroarray study. PMID: 12358776
Effects of single and repeated administration of methamphetamine or morphine on neuroglycan C gene expression in the rat brain. PMID: 16146580
Developmental changes in the biochemical and immunological characters of the carbohydrate moiety of neuroglycan C, a brain-specific chondroitin sulfate proteoglycan. PMID: 15115911
Transient expression of juvenile-type neurocan by reactive astrocytes in adult rat brains injured by kainate-induced seizures as well as surgical incision. PMID: 12088737
For research use only. Not for human or drug use.
