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Recombinant Human C1QB Protein, N-His-SUMO

Catalog #:   YHC00302 Specific References (104) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P02746
Protein length: Thr119-Ala253
Overview

Catalog No.

YHC00302

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Thr119-Ala253

Predicted molecular weight

27.65 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P02746

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Complement C1q subcomponent subunit B, C1QB

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Human C1QB protein
References

Exploring the Pathogenesis of Psoriasis Complicated With Atherosclerosis via Microarray Data Analysis. PMID: 34122426

Molecular Subgroups of Intrahepatic Cholangiocarcinoma Discovered by Single-Cell RNA Sequencing-Assisted Multiomics Analysis. PMID: 35604302

Complement C1q (C1qA, C1qB, and C1qC) May Be a Potential Prognostic Factor and an Index of Tumor Microenvironment Remodeling in Osteosarcoma. PMID: 34079754

Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages. PMID: 33782087

Network pharmacology and experimental validation-based approach to understand the effect and mechanism of Taohong Siwu Decoction against ischemic stroke. PMID: 35525530

Single cell analysis of cribriform prostate cancer reveals cell intrinsic and tumor microenvironmental pathways of aggressive disease. PMID: 36229464

Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19. PMID: 33138195

Screening of the Key Genes and Signalling Pathways for Diabetic Nephropathy Using Bioinformatics Analysis. PMID: 35923621

A Novel Diagnostic Predictive Model for Idiopathic Short Stature in Children. PMID: 34603204

TREM2 triggers microglial density and age-related neuronal loss. PMID: 30548312

Identification of Molecular Signatures and Candidate Drugs in Vascular Dementia by Bioinformatics Analyses. PMID: 35221911

Detection of Complement C1q B Chain Overexpression and Its Latent Molecular Mechanisms in Cervical Cancer Tissues Using Multiple Methods. PMID: 36313902

M2 macrophage-related gene signature in chronic rhinosinusitis with nasal polyps. PMID: 36466903

Identification of Key Diagnostic Markers and Immune Infiltration in Osteoarthritis. PMID: 35473522

Prognostic and immune-related value of complement C1Q (C1QA, C1QB, and C1QC) in skin cutaneous melanoma. PMID: 36110204

Investigation of the Mechanism of Complement System in Diabetic Nephropathy via Bioinformatics Analysis. PMID: 34124269

C1QA, C1QB, and GZMB are novel prognostic biomarkers of skin cutaneous melanoma relating tumor microenvironment. PMID: 36443341

Association of C1QB gene polymorphism with schizophrenia in Armenian population. PMID: 21951915

Jun, Gal, Cd74, and C1qb as potential indicator for neuropathic pain. PMID: 29331040

Genetic screening of early-onset patients with systemic lupus erythematosus by a targeted next-generation sequencing gene panel. PMID: 35086391

Integrative analysis of DNA methylation and gene expression profiles to identify biomarkers of glioblastoma. PMID: 34773808

Activation of complement C1q and C3 in glomeruli might accelerate the progression of diabetic nephropathy: Evidence from transcriptomic data and renal histopathology. PMID: 34932275

Identification of Key Biomarkers and Pathways for Maintaining Cognitively Normal Brain Aging Based on Integrated Bioinformatics Analysis. PMID: 35356296

Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimer's disease. PMID: 36180898

Development and Validation of a Prognostic Gene Signature Correlated With M2 Macrophage Infiltration in Esophageal Squamous Cell Carcinoma. PMID: 34926275

Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina. PMID: 36517889

IRF4-activated TEX41 promotes the malignant behaviors of melanoma cells by targeting miR-103a-3p/C1QB axis. PMID: 34915882

Identification of TYROBP and C1QB as Two Novel Key Genes With Prognostic Value in Gastric Cancer by Network Analysis. PMID: 33014868

[Research advances in the Cap gene of circovirus and its encoding capsid protein]. PMID: 23895015

Complement C1qB and C4 mRNAs responses to lesioning in rat brain. PMID: 1426121

Heat Shock Protein Upregulation Supplemental to Complex mRNA Alterations in Autoimmune Glaucoma. PMID: 36291747

Novel protein biomarkers associated with coronary artery disease in statin-treated patients with familial hypercholesterolemia. PMID: 28434814

Dysfunctional network of hub genes in hypertrophic cardiomyopathy patients. PMID: 36628247

Prognostic Implications of the Complement Protein C1q in Gliomas. PMID: 31649675

C1qB and clusterin mRNA increase in association with neurodegeneration in sporadic amyotrophic lateral sclerosis. PMID: 10471215

Expression of complement C1qB and C4 mRNAs during rat brain development. PMID: 7955342

Cerebrospinal fluid biomarkers for assessing Huntington disease onset and severity. PMID: 36523269

Characterization of C1q in teleosts: insight into the molecular and functional evolution of C1q family and classical pathway. PMID: 20615881

Evidence that complement and coagulation proteins are mediating the clinical response to omega-3 fatty acids: A mass spectrometry-based investigation in subjects at clinical high-risk for psychosis. PMID: 36307392

The identification of a novel splicing mutation in C1qB in a Japanese family with C1q deficiency: a case report. PMID: 24160257

Detection of molecular signatures and pathways shared by Alzheimer's disease and type 2 diabetes. PMID: 34813915

Transcriptome profiling of whole blood cells identifies PLEK2 and C1QB in human melanoma. PMID: 21698244

Complement component C1q is produced by isolated articular chondrocytes. PMID: 31634584

Variation in complement protein C1q is not a major contributor to cognitive impairment in Parkinson's disease. PMID: 25817358

Prognostic Implications of the Complement Protein C1Q and Its Correlation with Immune Infiltrates in Osteosarcoma. PMID: 33707956

In silico and in vitro studies on the protein-protein interactions between Brugia malayi immunomodulatory protein calreticulin and human C1q. PMID: 25184227

Induction of the complement component C1qB in brain of transgenic mice with neuronal overexpression of human cyclooxygenase-2. PMID: 11810182

Identification of a novel non-coding mutation in C1qB in a Dutch child with C1q deficiency associated with recurrent infections. PMID: 25454803

Anti-C1q autoantibodies specific against the globular domain of the C1qB-chain from patient with lupus nephritis inhibit C1q binding to IgG and CRP. PMID: 22209113

[Bioinformatics analysis identifies aging/senescence-induced genes in calcified plaques]. PMID: 36594382

Alteration of Serum Proteome in Levo-Thyroxine-Euthyroid Thyroidectomized Patients. PMID: 35330001

Selective expression of clusterin (SGP-2) and complement C1qB and C4 during responses to neurotoxins in vivo and in vitro. PMID: 7870303

Dysfunctional Network and Mutation Genes of Hypertrophic Cardiomyopathy. PMID: 35126952

Complement C1q expression in Erythema nodosum leprosum. PMID: 29499046

Molecular mechanisms for synchronized transcription of three complement C1q subunit genes in dendritic cells and macrophages. PMID: 21862594

Functional recombinant human complement C1q with different affinity tags. PMID: 33621564

Delayed inflammatory mRNA and protein expression after spinal cord injury. PMID: 21975064

GENETIC DELETION OF TRANSLOCATOR PROTEIN EXACERBATES POST-SEPSIS SYNDROME WITH ACTIVATION OF THE C1Q PATHWAY IN SEPTIC MOUSE MODEL. PMID: 36703279

Transcriptomic Analysis Reveals Genetic Cross-Talk between Periodontitis and Hypothyroidism. PMID: 35450027

Identification of key pathways and core genes involved in atherosclerotic plaque progression. PMID: 33708894

Comprehensive Genetic Analysis of Tuberculosis and Identification of Candidate Biomarkers. PMID: 35345666

Transforming growth factor-beta1 induces transforming growth factor-beta1 and transforming growth factor-beta receptor messenger RNAs and reduces complement C1qB messenger RNA in rat brain microglia. PMID: 11074155

[Screening and preliminary validation of biomarkers in sputum-negative pulmonary tuberculosis based on positron emission tomography/computed tomography and transcriptomics]. PMID: 35658381

Proteomics Analysis of Plasma-Derived Exosomes Unveils the Aberrant Complement and Coagulation Cascades in Dermatomyositis/Polymyositis. PMID: 36507906

Complement factors in adult peripheral nerve: a potential role in energy metabolism. PMID: 15145549

Identification of Genes with Altered Methylation in Osteoclast Differentiation and Its Roles in Osteoporosis. PMID: 35699379

Microarray-based analysis of renal complement components reveals a therapeutic target for lupus nephritis. PMID: 34433493

Bovine neonate is deficient in innate immunity at birth. PMID: 33640760

Exploring the pathogenesis of diabetic kidney disease by microarray data analysis. PMID: 36059966

Proteomic analysis of small extracellular vesicles from the plasma of patients with hepatocellular carcinoma. PMID: 36471393

Insomnia and depressive behavior of MyD88-deficient mice: Relationships with altered microglial functions. PMID: 34971898

Whole Exome Sequencing in Early-onset Systemic Lupus Erythematosus. PMID: 30008451

Subunits of C1Q Are Associated With the Progression of Intermittent Claudication to Chronic Limb-Threatening Ischemia. PMID: 35433866

Identification of plasma proteins associated with oesophageal cancer chemotherapeutic treatment outcomes using SWATH-MS. PMID: 35842220

Bioinformatics analysis of gene expression profiles of Inclusion body myositis. PMID: 32259312

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans. PMID: 19029902

Data-independent acquisition of the proteomics of spleens from chickens infected by avian leukosis virus. PMID: 31475084

Identification of Molecular Correlations Between DHRS4 and Progressive Neurodegeneration in Amyotrophic Lateral Sclerosis By Gene Co-Expression Network Analysis. PMID: 35479082

Genetic Profiles Related to Pathogenesis in Sporadic Intracranial Aneurysm Patients. PMID: 31238169

DNA methylation-based diagnostic and prognostic biomarkers of nasopharyngeal carcinoma patients. PMID: 32541515

Identification of an Alveolar Macrophage-Related Core Gene Set in Acute Respiratory Distress Syndrome. PMID: 34103966

Transcriptome analysis of human dorsal striatum implicates attenuated canonical WNT signaling in neuroinflammation and in age-related impairment of striatal neurogenesis and synaptic plasticity. PMID: 34275915

Analysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease. PMID: 26950848

Gene expression profile changes in rat dorsal horn after sciatic nerve injury. PMID: 28033741

[Biomarkers screening for viral myocarditis through proteomics analysis of plasma exosomes]. PMID: 30772974

Trajectory of change in brain complement factors from neonatal to young adult humans. PMID: 33190236

Identifying putative candidate genes and pathways involved in immune responses to porcine reproductive and respiratory syndrome virus (PRRSV) infection. PMID: 22486506

Identification of Reduced Host Transcriptomic Signatures for Tuberculosis Disease and Digital PCR-Based Validation and Quantification. PMID: 33763081

Identification of key genes and miRNAs related to polycystic ovary syndrome by comprehensive analysis of microarray. PMID: 36544152

C1q regulatory region polymorphism down-regulating murine c1q protein levels with linkage to lupus nephritis. PMID: 12133956

Increased complement C1q level marks active disease in human tuberculosis. PMID: 24647646

Identification of the Hub Genes Related to Nerve Injury-Induced Neuropathic Pain. PMID: 32508579

Reduced expression of innate immunity-related genes in lymph node metastases of luminal breast cancer patients. PMID: 33658651

Biosynthetic homeostasis and resilience of the complement system in health and infectious disease. PMID: 31262714

Extracellular vesicle proteomics and phosphoproteomics identify pathways for increased risk in patients hospitalized with COVID-19 and type 2 diabetes mellitus. PMID: 36736734

Bioinformatics Analysis of Potential Candidates for Therapy of TDRD7 Deficiency-Induced Congenital Cataract. PMID: 25997407

Histopathological comparison of the onset of peri-implantitis and periodontitis in rats. PMID: 26804139

Association of brain immune genes with social behavior of inbred mouse strains. PMID: 25895500

Red-Fleshed Apples Rich in Anthocyanins and White-Fleshed Apples Modulate the Aorta and Heart Proteome in Hypercholesterolaemic Rats: The AppleCOR Study. PMID: 35268023

Identification of novel gene and pathway targets for human epilepsy treatment. PMID: 26742644

Identification of dysregulated pathways underlying HTLV-1-associated myelopathy/tropical spastic paraparesis through co-expression network analysis. PMID: 33405203

Quantitative In-Depth Transcriptome Analysis Implicates Peritoneal Macrophages as Important Players in the Complement and Coagulation Systems. PMID: 35163105

Neuroinflammation in the pathogenesis of axonal Charcot-Marie-Tooth disease caused by lack of GDAP1. PMID: 31271761

The production and secretion of complement component C1q by human mast cells. PMID: 27648858

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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Recombinant Human C1QB Protein, N-His-SUMO [YHC00302]
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