Catalog No.
YHJ07702
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly71-Lys134
Predicted molecular weight
19.47 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6PUV4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Complexin II, Complexin-2, Synaphin-1, CPLX2, CPX II
Chronic mild stress-induced protein dysregulations correlated with susceptibility and resiliency to depression or anxiety revealed by quantitative proteomics of the rat prefrontal cortex. PMID: 33627638
Risk and protective effects of the complexin-2 gene and gene-environment interactions in schizophrenia. PMID: 25564026
CPLX2 Regulates Ferroptosis and Apoptosis Through NRF2 Pathway in Human Hepatocellular Carcinoma Cells. PMID: 36107387
Complexin 2 regulates secretion of immunoglobulin in antibody-secreting cells. PMID: 31691534
Complexin-2 (CPLX2) as a potential prognostic biomarker in human lung high grade neuroendocrine tumors. PMID: 23912489
Frontotemporal dysregulation of the SNARE protein interactome is associated with faster cognitive decline in old age. PMID: 29496544
Structural organization of the human complexin 2 gene (CPLX2) and aspects of its functional activity. PMID: 16162394
Clorgyline-mediated reversal of neurological deficits in a Complexin 2 knockout mouse. PMID: 20584925
Molecular evidence that cortical synaptic growth predominates during the first decade of life in humans. PMID: 20888897
[Effects of neonatal isolation stress on hyperlocomotion of complexin II knockout mouse]. PMID: 21861047
Association study of polymorphisms in synaptic vesicle-associated genes, SYN2 and CPLX2, with schizophrenia. PMID: 16131404
Expression of the synaptic exocytosis-regulating molecule complexin 2 in taste buds and its participation in peripheral taste transduction. PMID: 25692331
Modification of cognitive performance in schizophrenia by complexin 2 gene polymorphisms. PMID: 20819981
Complexin2 modulates working memory-related neural activity in patients with schizophrenia. PMID: 25297695
Identification of a minimal segment of complexin II essential for preferential distribution in axons. PMID: 19141077
Ginsenoside Rg1 Ameliorates Behavioral Abnormalities and Modulates the Hippocampal Proteomic Change in Triple Transgenic Mice of Alzheimer's Disease. PMID: 29204248
Establishment and validation of an aging-related risk signature associated with prognosis and tumor immune microenvironment in breast cancer. PMID: 36581948
A similar impairment in CA3 mossy fibre LTP in the R6/2 mouse model of Huntington's disease and in the complexin II knockout mouse. PMID: 16197510
Increased SNARE Protein-Protein Interactions in Orbitofrontal and Anterior Cingulate Cortices in Schizophrenia. PMID: 25662103
Complexin2 null mutation requires a 'second hit' for induction of phenotypic changes relevant to schizophrenia. PMID: 20412316
Orthosiphon stamineus Proteins Alleviate Pentylenetetrazol-Induced Seizures in Zebrafish. PMID: 32630817
No association of complexin1 and complexin2 genes with schizophrenia in a Japanese population. PMID: 16442780
An epigenome-wide DNA methylation study of patients with COVID-19. PMID: 34185889
Comprehensive analysis of gene mutation and expression profiles in neuroendocrine carcinomas of the stomach. PMID: 28239029
Whole transcriptome profiling of taste bud cells. PMID: 28790351
Insight into Glyproline Peptides' Activity through the Modulation of the Inflammatory and Neurosignaling Genetic Response Following Cerebral Ischemia-Reperfusion. PMID: 36553646
LCM-seq reveals unique transcriptional adaptation mechanisms of resistant neurons and identifies protective pathways in spinal muscular atrophy. PMID: 32820007
Age-dependent spatial memory loss can be partially restored by immune activation. PMID: 18803478
Identification of the common neurobiological process disturbed in genetic and non-genetic models for autism spectrum disorders. PMID: 36371739
Identification of potential candidate genes and regulatory pathways related to reproductive capacity in hypothalamus and pituitarium of male ducks (Anas platyrhynchos) by differential transcriptome analysis. PMID: 36315611
Effect of infliximab on gene expression profiling in Behcet's disease. PMID: 21862654
Effect of Fabomotizole on Brain Gene Expression in MR Rats in the Open Field Test. PMID: 31768849
Characterization of Different Subtypes of Immune Cell Infiltration in Glioblastoma to Aid Immunotherapy. PMID: 35799789
Case-control association study for 10 genes in patients with schizophrenia: influence of 5HTR1A variation rs10042486 on schizophrenia and response to antipsychotics. PMID: 22120873
Prognostic factor identification by analysis of the gene expression and DNA methylation data in glioma. PMID: 32987560
The orphan nuclear receptor TLX regulates hippocampal transcriptome changes induced by IL-1β. PMID: 29518529
Loganin substantially ameliorates molecular deficits, pathologies and cognitive impairment in a mouse model of Alzheimer's disease. PMID: 34689137
Candidate pathway association study in cocaine dependence: the control of neurotransmitter release. PMID: 21426264
Functional roles of complexin in neurotransmitter release at ribbon synapses of mouse retinal bipolar neurons. PMID: 25740533
Extenuation of in utero toxic effects of MeHg in the developing neurons by Fisetin via modulating the expression of synaptic transmission and plasticity regulators in hippocampus of the rat offspring. PMID: 30890323
The nuclear receptor coactivator AIB3 is a modulator of HOMA beta-cell function in nondiabetic children. PMID: 18462265
Co-Expression Analysis of Airway Epithelial Transcriptome in Asthma Patients with Eosinophilic vs. Non-Eosinophilic Airway Infiltration. PMID: 36835202
Rare copy number variation discovery and cross-disorder comparisons identify risk genes for ADHD. PMID: 21832240
[Structural and functional analyses of the Hfb1, Hmob3 and Hmob33 cDNAs as an example of human brain-specific gene studies]. PMID: 12723478
For research use only. Not for human or drug use.
