Downregulation of MEIS1 mediated by ELFN1-AS1/EZH2/DNMT3a axis promotes tumorigenesis and oxaliplatin resistance in colorectal cancer. PMID: 35351858
The Historical Relationship Between Meis1 and Leukemia. PMID: 35304708
MEIS1 and its potential as a cancer therapeutic target (Review). PMID: 34318904
Loss of Super-Enhancer-Regulated circRNA Nfix Induces Cardiac Regeneration After Myocardial Infarction in Adult Mice. PMID: 30947518
IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia. PMID: 35534777
DOT1L O-GlcNAcylation promotes its protein stability and MLL-fusion leukemia cell proliferation. PMID: 34551297
A calcineurin-Hoxb13 axis regulates growth mode of mammalian cardiomyocytes. PMID: 32499640
Meis1 supports leukemogenesis through stimulation of ribosomal biogenesis and Myc. PMID: 35546301
MEIS1 and Restless Legs Syndrome: A Comprehensive Review. PMID: 31551905
The emerging role of MEIS1 in cell proliferation and differentiation. PMID: 33296285
Meis1 promotes poly (rC)-binding protein 2 expression and inhibits angiotensin II-induced cardiomyocyte hypertrophy. PMID: 26597775
Homeobox gene Meis1 modulates cardiovascular regeneration. PMID: 31623926
Synergistic targeting of FLT3 mutations in AML via combined menin-MLL and FLT3 inhibition. PMID: 32589720
Prep1 and Meis1 competition for Pbx1 binding regulates protein stability and tumorigenesis. PMID: 24578510
Emerging Roles of Meis1 in Cardiac Regeneration, Stem Cells and Cancer. PMID: 28745213
HOXA9/MEIS1 targets in leukemia: reinforced signaling networks and therapeutic opportunities. PMID: 36005566
The SQSTM1-NUP214 fusion protein interacts with Crm1, activates Hoxa and Meis1 genes, and drives leukemogenesis in mice. PMID: 32343715
Role of MEIS1 in restless legs syndrome: From GWAS to functional studies in mice. PMID: 31229170
Dangerous liaisons: cooperation between Pbx3, Meis1 and Hoxa9 in leukemia. PMID: 26130510
MEIS1 functions as a potential AR negative regulator. PMID: 25158280
In vivo genome-wide CRISPR screening in murine acute myeloid leukemia uncovers microenvironmental dependencies. PMID: 35793392
HOXB13 interaction with MEIS1 modifies proliferation and gene expression in prostate cancer. PMID: 30560549
PREP1, MEIS1 homolog protein, regulates PF4 gene expression. PMID: 12732210
MEIS1 inhibits clear cell renal cell carcinoma cells proliferation and in vitro invasion or migration. PMID: 28270206
Expression of VEGFR-2 and Meis1 in the early stage of kidney cancers and its clinical significance. PMID: 33051419
Study of the dynamic expression of Meis1 in mice. PMID: 24639739
Members of the meis1 and pbx homeodomain protein families cooperatively bind a cAMP-responsive sequence (CRS1) from bovine CYP17. PMID: 9525891
MEIS1 promotes expression of stem cell markers in esophageal squamous cell carcinoma. PMID: 32819319
Hoxa9/meis1-transgenic zebrafish develops acute myeloid leukaemia-like disease with rapid onset and high penetrance. PMID: 36285442
Probe the relationship between BTBD9 and MEIS1 in C. elegans and mouse. PMID: 34268480
Elucidating the importance and regulation of key enhancers for human MEIS1 expression. PMID: 35624144
Meis1 plays roles in cortical development through regulation of cellular proliferative capacity in the embryonic cerebrum. PMID: 35718449
A tale of TALE, PREP1, PBX1, and MEIS1: Interconnections and competition in cancer. PMID: 28322463
Predicting the molecular role of MEIS1 in esophageal squamous cell carcinoma. PMID: 26314854
MOZ is critical for the development of MOZ/MLL fusion-induced leukemia through regulation of Hoxa9/Meis1 expression. PMID: 35947126
Deregulation of the HOXA9/MEIS1 axis in acute leukemia. PMID: 27258906
HOXA9 modulates its oncogenic partner Meis1 to influence normal hematopoiesis. PMID: 19620287
MEIS1 knockdown may promote differentiation of esophageal squamous carcinoma cell line KYSE-30. PMID: 31090196
Transcription factor Meis1 act as a new regulator of ischemic arrhythmias in mice. PMID: 35777912
The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo. PMID: 15882575
Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation. PMID: 29317485
Meis1: effects on motor phenotypes and the sensorimotor system in mice. PMID: 28645892
MEIS1-mediated transactivation of synaptotagmin-like 1 promotes CXCL12/CXCR4 signaling and leukemogenesis. PMID: 27018596
MEIS1 regulates early erythroid and megakaryocytic cell fate. PMID: 25107888
Down-regulation of MEIS1 promotes the maturation of oxidative phosphorylation in perinatal cardiomyocytes. PMID: 30884246
Meis1 is specifically upregulated in kidney myofibroblasts during aging and injury but is not required for kidney homeostasis or fibrotic response. PMID: 29592525
Meis1 preserves hematopoietic stem cells in mice by limiting oxidative stress. PMID: 23091297
MEIS1 regulates an HLF-oxidative stress axis in MLL-fusion gene leukemia. PMID: 25740828
Animal models of RLS phenotypes. PMID: 27839945
Identification of a conserved family of Meis1-related homeobox genes. PMID: 9049632
Restless in the mouse cage-A new genetic model for restless legs syndrome: An Editorial Highlight for "Deficiency of Meis1, a transcriptional regulator, in mice and worms:Neurochemical and behavioral characterizations with implications in the restless legs syndrome" on page 522. PMID: 33011998
Meis1 regulates postnatal cardiomyocyte cell cycle arrest. PMID: 23594737
Platelets take the lead in lymphatic separation. PMID: 20395601
MEIS1 down-regulation by MYC mediates prostate cancer development through elevated HOXB13 expression and AR activity. PMID: 32681068
Differential transcriptional regulation of meis1 by Gfi1b and its co-factors LSD1 and CoREST. PMID: 23308270
MEIS1 regulated proliferation and migration of pulmonary artery smooth muscle cells in hypoxia-induced pulmonary hypertension. PMID: 32450174
Sleep disturbance by pramipexole is modified by Meis1 in mice. PMID: 28695622
The role of meis1 in primitive and definitive hematopoiesis during zebrafish development. PMID: 21048033
Meis1 Is Required for Adult Mouse Erythropoiesis, Megakaryopoiesis and Hematopoietic Stem Cell Expansion. PMID: 26986211
MEIS1 intronic risk haplotype associated with restless legs syndrome affects its mRNA and protein expression levels. PMID: 19126776
Deficiency of Meis1, a transcriptional regulator, in mice and worms: Neurochemical and behavioral characterizations with implications in the restless legs syndrome. PMID: 32910473
Restless legs syndrome-associated MEIS1 risk variant influences iron homeostasis. PMID: 21710629
HOXA10 co-factor MEIS1 is required for the decidualization in human endometrial stromal cell. PMID: 32197234
Meis1 regulates epidermal stem cells and is required for skin tumorigenesis. PMID: 25013928
c-Met inhibition in a HOXA9/Meis1 model of CN-AML. PMID: 24307265
Pbx3 and Meis1 cooperate through multiple mechanisms to support Hox-induced murine leukemia. PMID: 25911551
Meis1, Hi1α, and GATA1 are integrated into a hierarchical regulatory network to mediate primitive erythropoiesis. PMID: 34496088
The role of Trib1 in myeloid leukaemogenesis and differentiation. PMID: 26517931
[Function of MEIS1 and miR-425 to the Regulating of Chronic Myeloid Leukemia Cell Proliferation]. PMID: 32552939
Homeobox transcription factor Meis1 is crucial to Sertoli cell mediated regulation of male fertility. PMID: 33145986
Meis1 coordinates a network of genes implicated in eye development and microphthalmia. PMID: 26253404
MEIS1 Regulates Hemogenic Endothelial Generation, Megakaryopoiesis, and Thrombopoiesis in Human Pluripotent Stem Cells by Targeting TAL1 and FLI1. PMID: 29358086
Flt3 is dispensable to the Hoxa9/Meis1 leukemogenic cooperation. PMID: 17202314
C-terminal domain of MEIS1 converts PKNOX1 (PREP1) into a HOXA9-collaborating oncoprotein. PMID: 21900201
MEIS1 Is a Common Transcription Repressor of the miR-23a and NORHA Axis in Granulosa Cells. PMID: 36834999
HOXA10, Pbx2, and Meis1 protein expression in the human endometrium: formation of multimeric complexes on HOXA10 target genes. PMID: 15494461
Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia. PMID: 28399410
Meis1 is critical to the maintenance of human acute myeloid leukemia cells independent of MLL rearrangements. PMID: 28054140
Correlation Between Meis1 and Msi1 in Esophageal Squamous Cell Carcinoma. PMID: 27142513
Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex. PMID: 21741595
Transcription Factor ELF1 Activates MEIS1 Transcription and Then Regulates the GFI1/FBW7 Axis to Promote the Development of Glioma. PMID: 33473327
An unexpected switch: regulation of cardiomyocyte proliferation by the homeobox gene meis1. PMID: 23868827
Pbx1, Meis1, and Runx1 Expression Is Decreased in the Diaphragmatic and Pulmonary Mesenchyme of Rats with Nitrofen-Induced Congenital Diaphragmatic Hernia. PMID: 32862424
Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells. PMID: 22995899
A role for MEIS1 in MLL-fusion gene leukemia. PMID: 19109563
Crosstalk between MEIS1 and markers of different cell signaling pathways in esophageal squamous cell carcinoma. PMID: 32372171
3D Chromatin Organization Involving MEIS1 Factor in the cis-Regulatory Landscape of GJB2. PMID: 35805969
Dynamic expression of MEIS1 homeoprotein in E14.5 forebrain and differentiated forebrain-derived neural stem cells. PMID: 23756022
meis1 regulates the development of endothelial cells in zebrafish. PMID: 18656453
The pancreatic and duodenal homeobox protein PDX-1 regulates the ductal specific keratin 19 through the degradation of MEIS1 and DNA binding. PMID: 20808819
Role of MAML1 and MEIS1 in Esophageal Squamous Cell Carcinoma Depth of Invasion. PMID: 28462489
Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice. PMID: 7565694
A knock-in mouse strain facilitates dynamic tracking and enrichment of MEIS1. PMID: 29296870
The homeobox gene MEIS1 is methylated in BRAF (p.V600E) mutated colon tumors. PMID: 24244575
MEIS1 variant as a determinant of autonomic imbalance in Restless Legs Syndrome. PMID: 28425489
Endothelin receptor emerges as a potential target of Hoxa9-mediated leukemogenesis. PMID: 30401485
Role of Retinoic Acid Signaling, FGF Signaling and Meis Genes in Control of Limb Development. PMID: 33435477
The human HOXA9 protein uses paralog-specific residues of the homeodomain to interact with TALE-class cofactors. PMID: 30952900
Regulation of MEIS1 by distal enhancer elements in acute leukemia. PMID: 24022755
A conserved tissue-specific homeodomain-less isoform of MEIS1 is downregulated in colorectal cancer. PMID: 21858198
Sox9-Meis1 Inactivation Is Required for Adipogenesis, Advancing Pref-1+ to PDGFRα+ Cells. PMID: 30355480
MicroRNAs mark in the MLL-rearranged leukemia. PMID: 23728610
Delineating MEIS1 cis-regulatory elements active in hematopoietic cells. PMID: 24097337
Menin inhibitors from monotherapies to combination therapies: clinical trial updates from 2024 ASH annual meeting., PMID:40528227
A locally aggressive pelvic MEIS1::NCOA1 fusion sarcoma in a young adult female: a case report and review of the literature., PMID:40420135
MEIS1: From functional versatility to post-transcriptional/translational regulation., PMID:40339957
MEIS1 knockdown upregulates WNT signaling pathway genes in esophageal squamous cell carcinoma., PMID:40211274
Inflammatory signaling pathways play a role in SYK inhibitor resistant AML., PMID:40188268
MEIS1::NCOA1 Primitive Spindle Cell Sarcoma of the Kidney : Report of 7 Cases of a Distinctive Clinicopathologic Entity., PMID:40160183
Pelvic spindle cell sarcomas harboring MEIS1::NCOA2 fusion and novel gene amplifications in 10q23-26 region: a potential predictor for tumor progression., PMID:40111447
Ubiquitous MEIS transcription factors actuate lineage-specific transcription to establish cell fate., PMID:40021842
Comparative analysis of the Mexico City Prospective Study and the UK Biobank identifies ancestry-specific effects on clonal hematopoiesis., PMID:39948438
MEIS1-mediated Apoptosis via TNFR1 in Endometriosis., PMID:39934615
Interaction Between Malat1 and miR-499-5p Regulates Meis1 Expression and Function with a Net Impact on Cell Proliferation., PMID:39851553
Integrated analysis of ATAC-seq and RNA-seq reveals the chromatin accessibility and transcriptional landscape of immunoglobulin a nephropathy., PMID:39848509
Oncogenic role of RARG rearrangements in acute myeloid leukemia resembling acute promyelocytic leukemia., PMID:39805831
MLL1 promotes placental trophoblast ferroptosis and aggravates preeclampsia symptoms through epigenetic regulation of RBM15/TRIM72/ADAM9 axis., PMID:39709463
Bleximenib, the novel menin-KMT2A inhibitor JNJ-75276617, impairs long-term proliferation and immune evasion in acute myeloid leukemia., PMID:39704147
Meis transcription factors regulate cardiac conduction system development and adult function., PMID:39691060
Integration of multi-omics layers empowers precision diagnosis through unveiling pathogenic mechanisms on maple syrup urine disease., PMID:39659154
TIFAB modulates metabolic pathways in KMT2A::MLLT3-induced AML through HNF4A., PMID:39626355
Targeting chromatin modifying complexes in acute myeloid leukemia., PMID:39607901
RLS-associated MEIS transcription factors control distinct processes in human neural stem cells., PMID:39578497
The regenerative effect of exosomes isolated from mouse embryonic fibroblasts in mice created as a sciatic nerve crush injury model., PMID:39388029
Epigenomic and Transcriptomic Profiling of Solitary Fibrous Tumors Identifies Site-Specific Patterns and Candidate Genes Regulated by DNA Methylation., PMID:39357799
Unraveling MLL1-fusion leukemia: Epigenetic revelations from an iPS cell point mutation., PMID:39342993
Identification of FDA-approved drugs that induce heart regeneration in mammals., PMID:39183959
Menin inhibitors in pediatric acute leukemia: a comprehensive review and recommendations to accelerate progress in collaboration with adult leukemia and the international community., PMID:39179671
Meis1 Targets Protein Tyrosine Phosphatase Receptor J in Fibroblast to Retard Chronic Kidney Disease Progression., PMID:39162106
Molecular basis of facilitated target search and sequence discrimination of TALE homeodomain transcription factor Meis1., PMID:39143123
The E3 ubiquitin ligase Herc1 modulates the response to nucleoside analogs in acute myeloid leukemia., PMID:39093953
Transcription factor Meis1b regulates craniofacial morphogenesis in zebrafish., PMID:39087648
Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A- and NPM1-altered leukemias., PMID:38905635
Disparity of gene expression in coronary artery disease: insights from MEIS1, HIRA, and Myocardin., PMID:38824221
A Comprehensive Analysis of HOXB13 Expression in Hepatocellular Carcinoma., PMID:38792899
Development of stemness-related signature to optimize prognosis prediction and identify XMD8-85 as a novel therapeutic compound for glioma., PMID:38768760
The Menin story in acute myeloid leukaemia-The road to success., PMID:38710595
Low-grade undifferentiated sarcoma with MEIS1::NCOA2-rearrangement primary to the lung: a case report., PMID:38678288
ERN1 knockdown modifies the hypoxic regulation of homeobox gene expression in U87MG glioblastoma cells., PMID:38563293
Potential drug targets for gastroesophageal reflux disease and Barrett's esophagus identified through Mendelian randomization analysis., PMID:38429412
MBNL1 Regulates Programmed Postnatal Switching Between Regenerative and Differentiated Cardiac States., PMID:38426339
Discovery of novel pyrrolo[2,3-d]pyrimidines as potent menin-mixed lineage leukemia interaction inhibitors., PMID:38367493
A patient-enriched MEIS1 coding variant causes a restless legs syndrome-like phenotype in mice., PMID:38314840
Therapeutic targeting in pediatric acute myeloid leukemia with aberrant HOX/MEIS1 expression., PMID:38174649
A mouse model of MEIS1-associated restless legs syndrome: insights and challenges., PMID:38150482
Methylation and transcriptomic expression profiles of HUVEC in the oxygen and glucose deprivation model and its clinical implications in AMI patients., PMID:38145212
Molecular mechanisms of pelvic organ prolapse influenced by FBLN5 via FOSL1/miR-222/MEIS1/COL3A1 axis., PMID:38056607
Transcriptional control of leukemogenesis by the chromatin reader SGF29., PMID:38048593
Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L., PMID:37958457
MEIS inhibitors reduce the viability of primary leukemia cells and Stem cells by inducing apoptosis., PMID:37902585
Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors., PMID:37890156
Differential transcriptional control of hematopoiesis in congenital and cyclic neutropenia patients harboring ELANE mutations., PMID:37855057
The effect Of vascular related CeRNA genes and corresponding imaging biomarkers on survival in lower grade glioma., PMID:37801268
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