Catalog No.
YHK91301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met2-Ser65
Predicted molecular weight
35.35 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9GZP1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Neurensin-2, C20orf98, NRSN2
NRSN2 promotes osteosarcoma cell proliferation and growth through PI3K/Akt/MTOR and Wnt/β-catenin signaling. PMID: 28401012
E2F1-activated NRSN2 promotes esophageal squamous cell carcinoma progression through AKT/mTOR pathway. PMID: 35662041
Highly expressed NRSN2 is related to malignant phenotype in ovarian cancer. PMID: 27908706
NRSN2 promotes non-small cell lung cancer cell growth through PI3K/Akt/mTOR pathway. PMID: 26045763
NRSN2 promotes breast cancer metastasis by activating PI3K/AKT/mTOR and NF-κB signaling pathways. PMID: 31885716
Down-Regulated NRSN2 Promotes Cell Proliferation and Survival Through PI3K/Akt/mTOR Pathway in Hepatocellular Carcinoma. PMID: 26055238
Long non-coding RNA NRSN2-AS1, transcribed by SOX2, promotes progression of esophageal squamous cell carcinoma by regulating the ubiquitin-degradation of PGK1. PMID: 35715622
Neurensin-2 promotes proliferation, invasion and migration of colorectal cancer cells via interaction with SOX12. PMID: 33193849
NRSN2 is a prognostic biomarker in gastric cancer and facilitates the growth and migration of gastric cancer cells. PMID: 36918782
Decreased expression of Neurensin-2 correlates with poor prognosis in hepatocellular carcinoma. PMID: 19824122
SOX12 and NRSN2 are candidate genes for 20p13 subtelomeric deletions associated with developmental delay. PMID: 24019301
Bone Marrow Mesenchymal Stem Cells-Derived Extracellular Vesicles Promote Proliferation, Invasion and Migration of Osteosarcoma Cells via the lncRNA MALAT1/miR-143/NRSN2/Wnt/β-Catenin Axis. PMID: 33564242
Phenotypic features of a microdeletion in chromosome band 20p13: A case report and review of the literature. PMID: 31087544
Transcriptome analysis reveals the mechanism of stromal cell-derived factor-1 and exendin-4 synergistically promoted periodontal ligament stem cells osteogenic differentiation. PMID: 34532163
Microenvironmental Hypoxia Induces Dynamic Changes in Lung Cancer Synthesis and Secretion of Extracellular Vesicles. PMID: 33050615
Long non-coding RNA NRSN2-AS1 facilitates tumorigenesis and progression of ovarian cancer via miR-744-5p/PRKX axis. PMID: 34791059
Extracellular vesicles from bone mesenchymal stem cells transport microRNA-206 into osteosarcoma cells and target NRSN2 to block the ERK1/2-Bcl-xL signaling pathway. PMID: 35730574
The exosomal transfer of human bone marrow mesenchymal stem cell-derived miR-1913 inhibits osteosarcoma progression by targeting NRSN2. PMID: 34650689
Prognostic and immunological role of sulfatide-related lncRNAs in hepatocellular carcinoma. PMID: 36816914
Prenatal diagnosis of 20p13 microdeletion syndrome. PMID: 33678341
For research use only. Not for human or drug use.
