Depletion of TMEM65 leads to oxidative stress, apoptosis, induction of mitochondrial unfolded protein response, and upregulation of mitochondrial protein import receptor TOMM22. PMID: 33319071
In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy. PMID: 29165030
A mitophagy-related gene signature associated with prognosis and immune microenvironment in colorectal cancer. PMID: 36333388
The prognostic value and clinical significance of mitophagy-related genes in hepatocellular carcinoma. PMID: 35991574
Mitochondrial accumulation of amyloid β (Aβ) peptides requires TOMM22 as a main Aβ receptor in yeast. PMID: 29925587
Knockdown of TMEM160 leads to an increase in reactive oxygen species generation and the induction of the mitochondrial unfolded protein response. PMID: 36217717
The mitochondrial import gene tomm22 is specifically required for hepatocyte survival and provides a liver regeneration model. PMID: 20483998
tomm22 Knockdown-Mediated Hepatocyte Damages Elicit Both the Formation of Hybrid Hepatocytes and Biliary Conversion to Hepatocytes in Zebrafish Larvae. PMID: 28251883
Catalpol promotes mitochondrial biogenesis in chondrocytes. PMID: 32096418
The TOMM machinery is a molecular switch in PINK1 and PARK2/PARKIN-dependent mitochondrial clearance. PMID: 24149440
Presequence protease reverses mitochondria-specific amyloid-β-induced mitophagy to protect mitochondria. PMID: 37002885
Phoenixin 20 promotes neuronal mitochondrial biogenesis via CREB-PGC-1α pathway. PMID: 32236796
The role of miRNAs and EBV BARTs in NPC. PMID: 22178394
TIM29 is a subunit of the human carrier translocase required for protein transport. PMID: 27718247
Quantitative analysis of the human ovarian carcinoma mitochondrial phosphoproteome. PMID: 31442208
Epstein-Barr Virus EBER Transcripts Affect miRNA-Mediated Regulation of Specific Targets and Are Processed to Small RNA Species. PMID: 29861423
Construction and Validation of Prognostic Regulation Network Based on RNA-Binding Protein Genes in Lung Squamous Cell Carcinoma. PMID: 34931870
The pro-apoptotic BH3-only protein Bim interacts with components of the translocase of the outer mitochondrial membrane (TOM). PMID: 25875815
A Novel Mitochondrial Complex of Aldosterone Synthase, Steroidogenic Acute Regulatory Protein, and Tom22 Synthesizes Aldosterone in the Rat Heart. PMID: 33526603
Structural basis of Tom20 and Tom22 cytosolic domains as the human TOM complex receptors. PMID: 35733257
Multistep assembly of the protein import channel of the mitochondrial outer membrane. PMID: 11276259
Identification and functional analysis of human Tom22 for protein import into mitochondria. PMID: 10982837
Exploring the dermotoxicity of the mycotoxin deoxynivalenol: combined morphologic and proteomic profiling of human epidermal cells reveals alteration of lipid biosynthesis machinery and membrane structural integrity relevant for skin barrier function. PMID: 33890134
Identification of potential target genes and related regulatory transcription factors in spontaneous hairline fracture induced by hypervitaminosis A. PMID: 28511966
Expression of the Bcl-2 family genes and complexes involved in the mitochondrial transport in prostate cancer cells. PMID: 25177836
Systematic analysis of viral and cellular microRNA targets in cells latently infected with human gamma-herpesviruses by RISC immunoprecipitation assay. PMID: 20413099
The m.13051G>A mitochondrial DNA mutation results in variable neurology and activated mitophagy. PMID: 27164671
Functional analysis of human metaxin in mitochondrial protein import in cultured cells and its relationship with the Tom complex. PMID: 11027586
Human AP endonuclease/redox factor APE1/ref-1 modulates mitochondrial function after oxidative stress by regulating the transcriptional activity of NRF1. PMID: 22580151
Isolation of functionally active and highly purified neuronal mitochondria from human cortex. PMID: 26808294
Bax inserts into the mitochondrial outer membrane by different mechanisms. PMID: 18687331
Impaired Mitochondrial Fusion and Oxidative Phosphorylation Triggered by High Glucose Is Mediated by Tom22 in Endothelial Cells. PMID: 31236191
Analysis of individual mitochondria via fluorescent immunolabeling with Anti-TOM22 antibodies. PMID: 24481619
The cytosolic domain of human Tom22 modulates human Bax mitochondrial translocation and conformation in yeast. PMID: 22198199
The mitochondrial BKCa channel cardiac interactome reveals BKCa association with the mitochondrial import receptor subunit Tom22, and the adenine nucleotide translocator. PMID: 27592226
Structural insights into proapoptotic signaling mediated by MTCH2, VDAC2, TOM40 and TOM22. PMID: 24269536
An Outer Mitochondrial Translocase, Tom22, Is Crucial for Inner Mitochondrial Steroidogenic Regulation in Adrenal and Gonadal Tissues. PMID: 26787839
Identification of mammalian TOM22 as a subunit of the preprotein translocase of the mitochondrial outer membrane. PMID: 10900208
Bcl-2 and porin follow different pathways of TOM-dependent insertion into the mitochondrial outer membrane. PMID: 12419260
Mitochondrial import receptors Tom20 and Tom22 have chaperone-like activity. PMID: 14699115
Mitochondrial targeting of cytochrome P450 proteins containing NH2-terminal chimeric signals involves an unusual TOM20/TOM22 bypass mechanism. PMID: 19401463
Biogenesis of the mitochondrial Tom40 channel in skeletal muscle from aged animals and its adaptability to chronic contractile activity. PMID: 20107041
Insertion and assembly of human tom7 into the preprotein translocase complex of the outer mitochondrial membrane. PMID: 12198123
An unusual TOM20/TOM22 bypass mechanism for the mitochondrial targeting of cytochrome P450 proteins containing N-terminal chimeric signals. PMID: 18480056
Targeting and assembly of rat mitochondrial translocase of outer membrane 22 (TOM22) into the TOM complex. PMID: 14985332
Conformation-sensitive gel electrophoresis as an ideal high-throughput strategy for accurate detection of sequence variations in DNA: screening hTomm and hTimm genes. PMID: 15475482
Metformin modulates the unfolded protein responses, altering lifespan and health-promoting effects in UPR-activated worms., PMID:40522955
Data independent acquisition reveals in-depth serum proteome changes in uremic pruritus., PMID:38577622
Mitochondrial Translocase TOMM22 Is Overexpressed in Pancreatic Cancer and Promotes Aggressive Growth by Modulating Mitochondrial Protein Import and Function., PMID:37878010
SARS-CoV-2 infection alters mitochondrial and cytoskeletal function in human respiratory epithelial cells mediated by expression of spike protein., PMID:37504520
TOMM40 and TOMM22 of the Translocase Outer Mitochondrial Membrane Complex rescue statin-impaired mitochondrial dynamics, morphology, and mitophagy in skeletal myotubes., PMID:37425714
Presequence protease reverses mitochondria-specific amyloid-β-induced mitophagy to protect mitochondria., PMID:37002885
A mitophagy-related gene signature associated with prognosis and immune microenvironment in colorectal cancer., PMID:36333388
Knockdown of TMEM160 leads to an increase in reactive oxygen species generation and the induction of the mitochondrial unfolded protein response., PMID:36217717
The prognostic value and clinical significance of mitophagy-related genes in hepatocellular carcinoma., PMID:35991574
Structural basis of Tom20 and Tom22 cytosolic domains as the human TOM complex receptors., PMID:35733257
Construction and Validation of Prognostic Regulation Network Based on RNA-Binding Protein Genes in Lung Squamous Cell Carcinoma., PMID:34931870
Exploring the dermotoxicity of the mycotoxin deoxynivalenol: combined morphologic and proteomic profiling of human epidermal cells reveals alteration of lipid biosynthesis machinery and membrane structural integrity relevant for skin barrier function., PMID:33890134
A Novel Mitochondrial Complex of Aldosterone Synthase, Steroidogenic Acute Regulatory Protein, and Tom22 Synthesizes Aldosterone in the Rat Heart., PMID:33526603
Depletion of TMEM65 leads to oxidative stress, apoptosis, induction of mitochondrial unfolded protein response, and upregulation of mitochondrial protein import receptor TOMM22., PMID:33319071
Phoenixin 20 promotes neuronal mitochondrial biogenesis via CREB-PGC-1α pathway., PMID:32236796
Catalpol promotes mitochondrial biogenesis in chondrocytes., PMID:32096418
Quantitative analysis of the human ovarian carcinoma mitochondrial phosphoproteome., PMID:31442208
Impaired Mitochondrial Fusion and Oxidative Phosphorylation Triggered by High Glucose Is Mediated by Tom22 in Endothelial Cells., PMID:31236191
Mitochondrial accumulation of amyloid β (Aβ) peptides requires TOMM22 as a main Aβ receptor in yeast., PMID:29925587
In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy., PMID:29165030
Identification of potential target genes and related regulatory transcription factors in spontaneous hairline fracture induced by hypervitaminosis A., PMID:28511966
tomm22 Knockdown-Mediated Hepatocyte Damages Elicit Both the Formation of Hybrid Hepatocytes and Biliary Conversion to Hepatocytes in Zebrafish Larvae., PMID:28251883
TIM29 is a subunit of the human carrier translocase required for protein transport., PMID:27718247
The mitochondrial BKCa channel cardiac interactome reveals BKCa association with the mitochondrial import receptor subunit Tom22, and the adenine nucleotide translocator., PMID:27592226
The m.13051G>A mitochondrial DNA mutation results in variable neurology and activated mitophagy., PMID:27164671
Isolation of functionally active and highly purified neuronal mitochondria from human cortex., PMID:26808294
An Outer Mitochondrial Translocase, Tom22, Is Crucial for Inner Mitochondrial Steroidogenic Regulation in Adrenal and Gonadal Tissues., PMID:26787839
Epstein-Barr Virus EBER Transcripts Affect miRNA-Mediated Regulation of Specific Targets and Are Processed to Small RNA Species., PMID:29861423
The pro-apoptotic BH3-only protein Bim interacts with components of the translocase of the outer mitochondrial membrane (TOM)., PMID:25875815
Expression of the Bcl-2 family genes and complexes involved in the mitochondrial transport in prostate cancer cells., PMID:25177836
Analysis of individual mitochondria via fluorescent immunolabeling with Anti-TOM22 antibodies., PMID:24481619
Structural insights into proapoptotic signaling mediated by MTCH2, VDAC2, TOM40 and TOM22., PMID:24269536
The TOMM machinery is a molecular switch in PINK1 and PARK2/PARKIN-dependent mitochondrial clearance., PMID:24149440
Human AP endonuclease/redox factor APE1/ref-1 modulates mitochondrial function after oxidative stress by regulating the transcriptional activity of NRF1., PMID:22580151
The cytosolic domain of human Tom22 modulates human Bax mitochondrial translocation and conformation in yeast., PMID:22198199
The role of miRNAs and EBV BARTs in NPC., PMID:22178394
The mitochondrial import gene tomm22 is specifically required for hepatocyte survival and provides a liver regeneration model., PMID:20483998
Systematic analysis of viral and cellular microRNA targets in cells latently infected with human gamma-herpesviruses by RISC immunoprecipitation assay., PMID:20413099
Biogenesis of the mitochondrial Tom40 channel in skeletal muscle from aged animals and its adaptability to chronic contractile activity., PMID:20107041
Mitochondrial targeting of cytochrome P450 proteins containing NH2-terminal chimeric signals involves an unusual TOM20/TOM22 bypass mechanism., PMID:19401463
Bax inserts into the mitochondrial outer membrane by different mechanisms., PMID:18687331
An unusual TOM20/TOM22 bypass mechanism for the mitochondrial targeting of cytochrome P450 proteins containing N-terminal chimeric signals., PMID:18480056
Conformation-sensitive gel electrophoresis as an ideal high-throughput strategy for accurate detection of sequence variations in DNA: screening hTomm and hTimm genes., PMID:15475482
Targeting and assembly of rat mitochondrial translocase of outer membrane 22 (TOM22) into the TOM complex., PMID:14985332
Mitochondrial import receptors Tom20 and Tom22 have chaperone-like activity., PMID:14699115
Bcl-2 and porin follow different pathways of TOM-dependent insertion into the mitochondrial outer membrane., PMID:12419260
Insertion and assembly of human tom7 into the preprotein translocase complex of the outer mitochondrial membrane., PMID:12198123
Multistep assembly of the protein import channel of the mitochondrial outer membrane., PMID:11276259
Functional analysis of human metaxin in mitochondrial protein import in cultured cells and its relationship with the Tom complex., PMID:11027586
Identification and functional analysis of human Tom22 for protein import into mitochondria., PMID:10982837
For research use only. Not for human or drug use.
