Catalog No.
YHD45702
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn311-Ser366
Predicted molecular weight
18.75 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P21452
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NK-2 receptor, NKNAR, Neurokinin A receptor, SKR, Tachykinin receptor 2, TACR2, TAC2R, Substance-K receptor, NK2R, NK-2R
DNA methylation of the Tacr2 gene in a CUMS model of depression. PMID: 30711443
TACR2 is associated with the immune microenvironment and inhibits migration and proliferation via the Wnt/β-catenin signaling pathway in prostate cancer. PMID: 34364377
Ablation of Tacr2 in mice leads to gastric emptying disturbance. PMID: 28585346
Congenital ablation of Tacr2 reveals overlapping and redundant roles of NK2R signaling in the control of reproductive axis. PMID: 33427049
No association of Tachykinin receptor 2 (TACR2) polymorphisms with Alzheimer's disease. PMID: 19375820
The expression of tachykinin receptors in the human lower esophageal sphincter. PMID: 26852958
Occurrence and pharmacological characterization of four human tachykinin NK2 receptor variants. PMID: 18601911
Prognostic Implications of Novel Gene Signatures in Gastric Cancer Microenvironment. PMID: 32740646
Expression of the tachykinin receptor mRNAs in healthy human colon. PMID: 18835556
Association of genetic variants in tachykinins pathway genes with colorectal cancer risk. PMID: 22733436
Altered expression of the tachykinins substance P/neurokinin A/hemokinin-1 and their preferred neurokinin 1/neurokinin 2 receptors in uterine leiomyomata. PMID: 27456549
Female Infertility Is Associated with an Altered Expression Profile of Different Members of the Tachykinin Family in Human Granulosa Cells. PMID: 35739351
The role of neurokinin A and its receptor in the regulation of prolactin secretion by the anterior pituitary of cyclic pigs. PMID: 32086962
The integrated hypothalamic tachykinin-kisspeptin system as a central coordinator for reproduction. PMID: 25422875
Ovarian steroids regulate tachykinin and tachykinin receptor gene expression in the mouse uterus. PMID: 19627578
A role for tachykinins in the regulation of human sperm motility. PMID: 17437961
LOC134466 methylation promotes oncogenesis of endometrial carcinoma through LOC134466/hsa-miR-196a-5p/TAC1 axis. PMID: 30485833
RNA-seq identifies differentially expressed genes involved in csal1 overexpression in granulosa cells of prehierarchical follicles in Chinese Dagu hens. PMID: 36442307
Distinct differences in tachykinin gene expression in ulcerative colitis, Crohn's disease and diverticular disease: a role for hemokinin-1? PMID: 21342363
Characterization of the Role of NKA in the Control of Puberty Onset and Gonadotropin Release in the Female Mouse. PMID: 31504389
Transcriptomic Profiles of Brain Provide Insights into Molecular Mechanism of Feed Conversion Efficiency in Crucian Carp (Carassius auratus). PMID: 29538345
Functional and molecular characterization of tachykinins and tachykinin receptors in the mouse uterus. PMID: 15647454
Induction of the neurokinin 1 receptor by TNFα in endometriotic tissue provides the potential for neurogenic control over endometriotic lesion growth. PMID: 23553861
Tracing the pathways and mechanisms involved in the anti-breast cancer activity of glycyrrhizin using bioinformatics tools and computational methods. PMID: 37042955
Application of HapMap data to the evaluation of 8 candidate genes for pediatric slow transit constipation. PMID: 17448763
Discovery, Synthesis, Pharmacological Profiling, and Biological Characterization of Brintonamides A-E, Novel Dual Protease and GPCR Modulators from a Marine Cyanobacterium. PMID: 30015488
For research use only. Not for human or drug use.
