The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagy. PMID: 34130600
RNA-Binding Protein MEX3A Interacting with DVL3 Stabilizes Wnt/β-Catenin Signaling in Endometrial Carcinoma. PMID: 36614043
WNT/PCP signaling pathway and human cancer (review). PMID: 16273260
Autosomal Dominant Robinow Syndrome. PMID: 25577943
Role and mechanism of Dvl3 in the esophageal squamous cell carcinoma. PMID: 30536315
Exosomal Dvl3 promoted the aggressive phenotypic transformation of RA-FLS via wnt pathway. PMID: 35499309
Polymorphism and expression of the Dvl3 gene in the etiology of depressive disorder. PMID: 33038884
Dishevelled segment polarity protein 3 (DVL3): a novel and easily applicable recurrence predictor in localised prostate adenocarcinoma. PMID: 28107606
Expression Levels and Localizations of DVL3 and sFRP3 in Glioblastoma. PMID: 29200599
Circ_0101802 Facilitates Colorectal Cancer Progression Depending on the Regulation of miR-665/DVL3 Signaling. PMID: 35314912
Planar cell polarity protein Dishevelled 3 (Dvl3) regulates ectoplasmic specialization (ES) dynamics in the testis through changes in cytoskeletal organization. PMID: 30808893
Aberrant expression of SFRP1, SFRP3, DVL2 and DVL3 Wnt signaling pathway components in diffuse gastric carcinoma. PMID: 34691249
Silencing DVL3 defeats MTX resistance and attenuates stemness via Notch Signaling Pathway in colorectal cancer. PMID: 32414668
Dsh homolog DVL3 mediates resistance to IGFIR inhibition by regulating IGF-RAS signaling. PMID: 25168481
DVL1 and DVL3 require nuclear localisation to regulate proliferation in human myoblasts. PMID: 35589804
LncRNA BLACAT1 Promotes Proliferation, Migration and Invasion of Prostate Cancer Cells via Regulating miR-29a-3p/DVL3 Axis. PMID: 33641528
Different behaviour of DVL1, DVL2, DVL3 in astrocytoma malignancy grades and their association to TCF1 and LEF1 upregulation. PMID: 30468298
Autosomal dominant Robinow syndrome associated with a novel DVL3 splice mutation. PMID: 29575616
The Gender-Specific Interaction of DVL3 and GSK3β Polymorphisms on Major Depressive Disorder Susceptibility in a Chinese Han Population: A Case-Control Study. PMID: 35126809
LncRNA testis-specific transcript, Y-linked 15 (TTTY15) promotes proliferation, migration and invasion of colorectal cancer cells via regulating miR-29a-3p/DVL3 axis. PMID: 33016900
DVL3 Alleles Resulting in a -1 Frameshift of the Last Exon Mediate Autosomal-Dominant Robinow Syndrome. PMID: 26924530
AMPK activators suppress breast cancer cell growth by inhibiting DVL3-facilitated Wnt/β-catenin signaling pathway activity. PMID: 28035400
AMPK activators suppress cervical cancer cell growth through inhibition of DVL3 mediated Wnt/β-catenin signaling activity. PMID: 23301094
Chondrocyte Polarity During Endochondral Ossification Requires Protein-Protein Interactions Between Prickle1 and Dishevelled2/3. PMID: 34423861
[Wnt Signaling and Skeletal Dysplasias.]. PMID: 30814377
Dvl3 polymorphism interacts with life events and pro-inflammatory cytokines to influence major depressive disorder susceptibility. PMID: 30242173
Disheveled3 enhanced EMT and cancer stem-like cells properties via Wnt/β-catenin/c-Myc/SOX2 pathway in colorectal cancer. PMID: 37147666
TLR4 induced Wnt3a-Dvl3 restrains the intensity of inflammation and protects against endotoxin-driven organ failure through GSK3β/β-catenin signaling. PMID: 31884387
Dvl3 translocates IPMK to the cell membrane in response to Wnt. PMID: 22940627
ALFY-Controlled DVL3 Autophagy Regulates Wnt Signaling, Determining Human Brain Size. PMID: 27008544
Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs. PMID: 31870452
Dishevelled coordinates phosphoinositide kinases PI4KIIIα and PIP5KIγ for efficient PtdInsP2 synthesis. PMID: 34982154
PCP Protein Inversin Regulates Testis Function Through Changes in Cytoskeletal Organization of Actin and Microtubules. PMID: 35106541
Protein tyrosine kinase 7-knockdown inhibits oral squamous cell carcinoma cell viability, proliferation, migration and invasion via downregulating dishevelled segment polarity protein 3 expression. PMID: 34659518
Dishevelled: A masterful conductor of complex Wnt signals. PMID: 29559363
miR-204-5p promotes the adipogenic differentiation of human adipose-derived mesenchymal stem cells by modulating DVL3 expression and suppressing Wnt/β-catenin signaling. PMID: 25847080
Brain metastases from lung cancer show increased expression of DVL1, DVL3 and beta-catenin and down-regulation of E-cadherin. PMID: 24933634
Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma. PMID: 28455968
Dishevelled Paralogs in Vertebrate Development: Redundant or Distinct? PMID: 28603713
Gene expression in major depressive disorder. PMID: 26008736
RPGR protein complex regulates proteasome activity and mediates store-operated calcium entry. PMID: 29796181
DVL1 and DVL3 differentially localize to CYP19A1 promoters and regulate aromatase mRNA in breast cancer cells. PMID: 30479694
E2F1-activated LINC01224 drives esophageal squamous cell carcinoma cell malignant behaviors via targeting miR-6884-5p/DVL3 axis and activating Wnt/β-catenin signaling pathway. PMID: 35576835
Assembly of Dishevelled 3-based supermolecular complexes via phosphorylation and Axin. PMID: 22748080
Wnt-dependent assembly of supermolecular Dishevelled-3-based complexes. PMID: 20940260
Dishevelled family proteins in serous ovarian carcinomas: a clinicopathologic and molecular study. PMID: 31755579
Hsa-miR-143-3p inhibits Wnt-β-catenin and MAPK signaling in human corneal epithelial stem cells. PMID: 35794158
Dishevelled family proteins (DVL1-3) expression in intrauterine growth restriction (IUGR) placentas. PMID: 33485290
Construction and Validation of a Protein-associated Prognostic Model for Gastrointestinal Cancer. PMID: 35430986
Dishevelled C-terminus: prolyl and histidinyl motifs. PMID: 21535414
MSX1 induces the Wnt pathway antagonist genes DKK1, DKK2, DKK3, and SFRP1 in neuroblastoma cells, but does not block Wnt3 and Wnt5A signalling to DVL3. PMID: 19815336
Circadian gene CSNK1D promoted the progression of hepatocellular carcinoma by activating Wnt/β-catenin pathway via stabilizing Dishevelled Segment Polarity Protein 3. PMID: 36460966
A Proteomics Study of the Subacute Toxicity of Rat Brain after Long- Term Exposure of Gelsemium elegans. PMID: 34886788
Prickle-1 negatively regulates Wnt/beta-catenin pathway by promoting Dishevelled ubiquitination/degradation in liver cancer. PMID: 17030191
WNT5A: a motility-promoting factor in Hodgkin lymphoma. PMID: 27270428
Functional analysis of dishevelled-3 phosphorylation identifies distinct mechanisms driven by casein kinase 1ϵ and frizzled5. PMID: 24993822
Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3. PMID: 18093802
De novo variants of CSNK2B cause a new intellectual disability-craniodigital syndrome by disrupting the canonical Wnt signaling pathway. PMID: 35571680
Secreted Frizzled Related Protein 2 Modulates Epithelial-Mesenchymal Transition and Stemness via Wnt/β-Catenin Signaling in Choriocarcinoma. PMID: 30396168
Abnormal WNT5A Signaling Causes Mandibular Hypoplasia in Robinow Syndrome. PMID: 28662348
Nuclear Dishevelled targets gene regulatory regions and promotes tumor growth. PMID: 33860601
The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer. PMID: 31831834
Structural Elucidation of Peptide Binding to KLHL-12, a Substrate Specific Adapter Protein in a Cul3-Ring E3 Ligase Complex. PMID: 32032490
Dishevelled stability is positively regulated by PKCζ-mediated phosphorylation induced by Wnt agonists. PMID: 28366812
Systematic mapping of WNT-FZD protein interactions reveals functional selectivity by distinct WNT-FZD pairs. PMID: 25605717
Let-7c inhibits cholangiocarcinoma growth but promotes tumor cell invasion and growth at extrahepatic sites. PMID: 29445149
Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells. PMID: 10806215
Beta-Catenin mediates the anti-adipogenic effect of baicalin. PMID: 20627088
Cripto-1 contributes to stemness in hepatocellular carcinoma by stabilizing Dishevelled-3 and activating Wnt/β-catenin pathway. PMID: 29445127
Roles of individual human Dishevelled paralogs in the Wnt signalling pathways. PMID: 34082011
Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development. PMID: 19008950
Signaling crosstalk between TGFβ and Dishevelled/Par1b. PMID: 22576663
Immunological classification of hepatitis B virus-positive hepatocellular carcinoma by transcriptome analysis. PMID: 36618328
Differential Expression of Wnt Pathway Genes in Sporadic Hepatocellular Carcinomas Infected With Hepatitis B Virus Identified With OligoGE Arrays. PMID: 23483081
Helicobacter pylori-induced activation of beta-catenin involves low density lipoprotein receptor-related protein 6 and Dishevelled. PMID: 20137080
HECT (Homologous to the E6-AP Carboxyl Terminus)-Type Ubiquitin E3 Ligase ITCH Attenuates Cardiac Hypertrophy by Suppressing the Wnt/β-Catenin Signaling Pathway. PMID: 33131309
Clinical and molecular characterization of four patients with Robinow syndrome from different families. PMID: 33496066
CELSR1 Is a Positive Regulator of Endothelial Cell Migration and Angiogenesis. PMID: 27301287
Delicate analysis of post-translational modifications on Dishevelled 3. PMID: 22612246
Canine DVL2 variant contributes to brachycephalic phenotype and caudal vertebral anomalies. PMID: 33599851
A multi-mode Wnt- and stemness-regulatory module dictated by FOXM1 and ASPM isoform I in gastric cancer. PMID: 33515163
Ethanol affects differentiation-related pathways and suppresses Wnt signaling protein expression in human neural stem cells. PMID: 22150777
Novel pathogenic genomic variants leading to autosomal dominant and recessive Robinow syndrome. PMID: 33048444
Cigarette smoke induces promoter methylation of single-stranded DNA-binding protein 2 in human esophageal squamous cell carcinoma. PMID: 20658532
Targeting methyltransferase PRMT5 eliminates leukemia stem cells in chronic myelogenous leukemia. PMID: 27643437
Integrative genomics analysis identifies candidate drivers at 3q26-29 amplicon in squamous cell carcinoma of the lung. PMID: 23908357
The origins of rimmed vacuoles and granulovacuolar degeneration bodies are associated with the Wnt signaling pathway. PMID: 27939356
SOX2 promotes tumor metastasis by stimulating epithelial-to-mesenchymal transition via regulation of WNT/β-catenin signal network. PMID: 23545177
Personalised Medicine for Colorectal Cancer Using Mechanism-Based Machine Learning Models. PMID: 34576133
Expression of dishevelled gene in Hirschsprung's disease. PMID: 24040443
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