ZHX2 promotes HIF1α oncogenic signaling in triple-negative breast cancer. PMID: 34779768
USP13 promotes deubiquitination of ZHX2 and tumorigenesis in kidney cancer. PMID: 36037364
Zhx2 Accelerates Sepsis by Promoting Macrophage Glycolysis via Pfkfb3. PMID: 32179636
VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma. PMID: 30026228
Transcription factor Zhx2 restricts NK cell maturation and suppresses their antitumor immunity. PMID: 34279541
ZHX2 in health and disease. PMID: 36465389
The transcription factor zinc fingers and homeoboxes 2 alleviates NASH by transcriptional activation of phosphatase and tensin homolog. PMID: 34545586
HNRNPD interacts with ZHX2 regulating the vasculogenic mimicry formation of glioma cells via linc00707/miR-651-3p/SP2 axis. PMID: 33542193
Zhx2 (zinc fingers and homeoboxes 2) regulates major urinary protein gene expression in the mouse liver. PMID: 28258223
ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14. PMID: 35151335
The zinc fingers and homeoboxes 2 protein ZHX2 and its interacting proteins regulate upstream pathways in podocyte diseases. PMID: 32059999
ZHX2 mediates proteasome inhibitor resistance via regulating nuclear translocation of NF-κB in multiple myeloma. PMID: 32780537
ZHX2 inhibits proliferation and promotes apoptosis of human lung cancer cells through targeting p38MAPK pathway. PMID: 31683461
ZHX2 inhibits SREBP1c-mediated de novo lipogenesis in hepatocellular carcinoma via miR-24-3p. PMID: 32770671
Tumor suppressor ZHX2 inhibits NAFLD-HCC progression via blocking LPL-mediated lipid uptake. PMID: 31740790
Low expression of ZHX1 and ZHX2 impacts on the prognosis of chronic lymphocytic leukemia. PMID: 33541423
Upregulation of ZHX2 predicts poor prognosis and is correlated with immune infiltration in gastric cancer. PMID: 33837660
Novel regulation of the transcription factor ZHX2 by N-terminal methylation. PMID: 35613330
HBV suppresses ZHX2 expression to promote proliferation of HCC through miR-155 activation. PMID: 29752719
ZHX2 restricts hepatocellular carcinoma by suppressing stem cell-like traits through KDM2A-mediated H3K36 demethylation. PMID: 32114388
Transcription Factor Zhx2 Deficiency Reduces Atherosclerosis and Promotes Macrophage Apoptosis in Mice. PMID: 30026271
ZHX2 is a repressor of alpha-fetoprotein expression in human hepatoma cell lines. PMID: 18194454
The role of Zhx2 transcription factor in bipolar cell differentiation during mouse retinal development. PMID: 30146259
ZHX2 drives cell growth and migration via activating MEK/ERK signal and induces Sunitinib resistance by regulating the autophagy in clear cell Renal Cell Carcinoma. PMID: 32382017
ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA. PMID: 25473899
Tumor suppressor ZHX2 restricts hepatitis B virus replication via epigenetic and non-epigenetic manners. PMID: 29580980
ZHX2 and ZHX3 repress cancer markers in normal hepatocytes. PMID: 19273305
LINC01431 Promotes Histone H4R3 Methylation to Impede HBV Covalently Closed Circular DNA Transcription by Stabilizing PRMT1. PMID: 35398991
Reduced nucleic ZHX2 involves in oncogenic activation of glypican 3 in human hepatocellular carcinoma. PMID: 25195714
Zinc fingers and homeoboxes 2 is required for diethylnitrosamine-induced liver tumor formation in C57BL/6 mice. PMID: 36194180
Zhx2 Is a Candidate Gene Underlying Oxymorphone Metabolite Brain Concentration Associated with State-Dependent Oxycodone Reward. PMID: 35688478
[Role of ZHX2 in regulating dorsal root ganglion μ-opioid receptor expression in mice with peripheral nerve injuryinduced pain hypersensitivity]. PMID: 31511211
Promoter hypermethylation of a novel gene, ZHX2, in hepatocellular carcinoma. PMID: 16707376
Cytokine storm-based mechanisms for extrapulmonary manifestations of SARS-CoV-2 infection. PMID: 37040185
Zinc Fingers and Homeoboxes 2 (Zhx2) Regulates Sexually Dimorphic Cyp Gene Expression in the Adult Mouse Liver. PMID: 27197076
[The methylation of ZHX2 gene promoter enhances AFP gene expression in hepatocellular carcinoma]. PMID: 23837980
Transcriptional deregulation of homeobox gene ZHX2 in Hodgkin lymphoma. PMID: 22078940
The mouse zinc-fingers and homeoboxes (ZHX) family; ZHX2 forms a heterodimer with ZHX3. PMID: 14659886
ZHX2 Interacts with Ephrin-B and regulates neural progenitor maintenance in the developing cerebral cortex. PMID: 19515908
Targeting genes and signaling pathways of transcriptional suppressor ZHX2 in hepatocellular carcinoma: a Chromatin Immunoprecipitation-sequencing (ChIP-seq) investigation. PMID: 30784286
Expression of zinc-fingers and homeoboxes 2 in hepatocellular carcinogenesis: a tissue microarray and clinicopathological analysis. PMID: 17447851
Zhx2 and Zbtb20: novel regulators of postnatal alpha-fetoprotein repression and their potential role in gene reactivation during liver cancer. PMID: 21216289
Zinc fingers and homeoboxes 2 inhibits hepatocellular carcinoma cell proliferation and represses expression of Cyclins A and E. PMID: 22406477
Liver size and lipid content differences between BALB/c and BALB/cJ mice on a high-fat diet are due, in part, to Zhx2. PMID: 31321500
Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor. PMID: 12741956
Hepatitis B virus X protein promotes CREB-mediated activation of miR-3188 and Notch signaling in hepatocellular carcinoma. PMID: 28574502
t(4;8)(q27;q24) in Hodgkin lymphoma cells targets phosphodiesterase PDE5A and homeobox gene ZHX2. PMID: 21987443
Quantitative trait locus mapping and identification of Zhx2 as a novel regulator of plasma lipid metabolism. PMID: 20160197
Zinc fingers and homeoboxes 2 inhibition could suppress the proliferation of ovarian cancer cells by apoptosis pathway. PMID: 36746874
Zinc Fingers and Homeobox Family in Cancer: A Double-Edged Sword. PMID: 36232466
Regulation of cell differentiation by Eph receptor and ephrin signaling. PMID: 25482623
Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains. PMID: 20509910
Hereditary persistence of alpha-fetoprotein and H19 expression in liver of BALB/cJ mice is due to a retrovirus insertion in the Zhx2 gene. PMID: 15626755
Key emerging issues in progressive supranuclear palsy and corticobasal degeneration. PMID: 25701010
Proliferation and osteo/odontogenic differentiation of stem cells from apical papilla regulated by Zinc fingers and homeoboxes 2: An in vitro study. PMID: 26679602
Low expression of ZHX2, but not RCBTB2 or RAN, is associated with poor outcome in multiple myeloma. PMID: 18353163
Cystathionine β-synthase gene inactivation dysregulates major urinary protein biogenesis and impairs sexual signaling in mice. PMID: 36098436
Attenuated ZHX3 expression serves as a potential biomarker that predicts poor clinical outcomes in breast cancer patients. PMID: 30787639
Transcriptional control in the mammalian liver: liver development, perinatal repression, and zonal gene regulation. PMID: 17041810
Development and validation of novel prognostic models for zinc finger proteins-related genes in soft tissue sarcoma. PMID: 37100454
Evolutionary Analysis of the Zinc Finger and Homeoboxes Family of Proteins Identifies Multiple Conserved Domains and a Common Early Chordate Ancestor. PMID: 32125369
Lack of association of G779A ZHX-2 gene variant with HbF levels in β-thalassemia major. PMID: 21443521
Bioinformatic analysis linking genomic defects to chemosensitivity and mechanism of action. PMID: 33909629
Microarray Genotyping Identifies New Loci Associated with Dementia in Parkinson's Disease. PMID: 34946922
The oncofetal gene glypican 3 is regulated in the postnatal liver by zinc fingers and homeoboxes 2 and in the regenerating liver by alpha-fetoprotein regulator 2. PMID: 17668883
Deregulated FOX genes in Hodgkin lymphoma. PMID: 25043849
Allele-specific expression in the human heart and its application to postoperative atrial fibrillation and myocardial ischemia. PMID: 27923400
LncRNA PART1 Promotes Proliferation and Migration, Is Associated with Cancer Stem Cells, and Alters the miRNA Landscape in Triple-Negative Breast Cancer. PMID: 34072264
Prognostic value and therapeutic implications of ZHX family member expression in human gastric cancer. PMID: 32774706
ZBTB20 is involved in liver regeneration after partial hepatectomy in mouse. PMID: 24463079
Expression and prognostic significance of zinc fingers and homeoboxes family members in renal cell carcinoma. PMID: 28152006
Expression of new red cell-related genes in erythroid differentiation. PMID: 19941055
Chromatin structure regulates cancer-specific alternative splicing events in primary HPV-related oropharyngeal squamous cell carcinoma. PMID: 32164487
Genome-wide association study of antibody response to smallpox vaccine. PMID: 22542470
Prevalence of chromosomal rearrangements involving non-ETS genes in prostate cancer. PMID: 25625310
Aberrantly Expressed OTX Homeobox Genes Deregulate B-Cell Differentiation in Hodgkin Lymphoma. PMID: 26406991
Expression patterns of homeobox genes in the mouse vomeronasal organ at postnatal stages. PMID: 27521061
Increased DNA Methylation and Reduced Expression of Transcription Factors in Human Osteoarthritis Cartilage. PMID: 26881698
Loss of liver-specific and sexually dimorphic gene expression by aryl hydrocarbon receptor activation in C57BL/6 mice. PMID: 28922406
ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome. PMID: 17056598
A missense mutation in podocin leads to early and severe renal disease in mice. PMID: 18288100
Anti-TROVE2 Antibody Determined by Immune-Related Array May Serve as a Predictive Marker for Adalimumab Immunogenicity and Effectiveness in RA. PMID: 33763493
Hypermethylation of EBF3 and IRX1 genes in synovial fibroblasts of patients with rheumatoid arthritis. PMID: 23456299
Construction of a recombinant eukaryotic human ZHX1 gene expression plasmid and the role of ZHX1 in hepatocellular carcinoma. PMID: 24064680
Investigating the genetic profile of familial atypical cystic fibrosis patients (DeltaF508-CFTR) with neonatal biliary atresia. PMID: 36205856
Early changes in gene expression that influence the course of primary glomerular disease. PMID: 17457373
PreImplantation factor (PIF*) promotes embryotrophic and neuroprotective decidual genes: effect negated by epidermal growth factor. PMID: 26085845
Characterization of early stages of human B cell development by gene expression profiling. PMID: 17785802
Analysis of adult cerebral cortex and hippocampus transcriptomes reveals unique molecular changes in the Ts1Cje mouse model of down syndrome. PMID: 24916381
Genetic association and gene-smoking interaction study of carotid intima-media thickness at five GWAS-indicated genes: the Bogalusa Heart Study. PMID: 25746325
The tandem zinc-finger region of human ZHX adopts a novel C2H2 zinc finger structure with a C-terminal extension. PMID: 19348505
Expression of RAN, ZHX-2, and CHC1L genes in multiple myeloma patients and in myeloma cell lines treated with HDAC and Dnmts inhibitors. PMID: 20568903
Identification of novel candidate genes for globin regulation in erythroid cells containing large deletions of the human beta-globin gene cluster. PMID: 16952470
Prenatal diagnosis and array comparative genomic hybridization characterization of interstitial deletions of 8q23.3-q24.11 and 8q24.13 associated with Langer-Giedion syndrome, Cornelia de Lange syndrome and haploinsufficiency of TRPS1, RAD21 and EXT1. PMID: 26522117
Hypoxia-specific transcriptional condensates drive metastasis., PMID:40379526
Validation studies and multiomics analysis of Zhx2 as a candidate quantitative trait gene underlying brain oxycodone metabolite (oxymorphone) levels and behavior., PMID:40215834
Aquaporin 9 downregulation in KRASG12V colorectal cancer and associated with increased proliferation and decreased apoptosis in cancer cells., PMID:40210882
Hypoxia-induced phase separation of ZHX2 alters chromatin looping to drive cancer metastasis., PMID:40185097
The Hippo pathway effector YAP inhibits NF-κB signaling and ccRCC growth by opposing ZHX2., PMID:40120683
ZHX2 inhibits diabetes-induced liver injury and ferroptosis by epigenetic silence of YTHDF2., PMID:39987125
Sex-specific DNA methylation marks associated with sex-biased risk of recurrence in unprovoked venous thromboembolism., PMID:39848545
Identification of methylation-sensitive human transcription factors using meSMiLE-seq., PMID:39605503
METTL3 and IGF2BP1-Mediated m6A Modification of ZHX2 Promotes Tumor Property of Renal Cell Carcinoma., PMID:39159608
Editorial: Transcription factors in immunological disease and haematological malignancies., PMID:38881890
Transcriptional Landscape of CUT-Class Homeobox Genes in Blastic Plasmacytoid Dendritic Cell Neoplasm., PMID:38474011
ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury., PMID:37980429
Elongation of very long chain fatty acids-3 (Elovl3) is activated by ZHX2 and is a regulator of cell cycle progression., PMID:37847682
"Idiopathic" minimal change nephrotic syndrome: a podocyte mystery nears the end., PMID:37795536
Transcription factor Zhx2 is a checkpoint that programs macrophage polarization and antitumor response., PMID:37582865
ZHX2 deficiency enriches hybrid MET cells through regulating E-cadherin expression., PMID:37460540
Zhx2 maintains islet β-cell mass and function by transcriptionally regulating Pax6., PMID:37275527
Development and validation of novel prognostic models for zinc finger proteins-related genes in soft tissue sarcoma., PMID:37100454
Cytokine storm-based mechanisms for extrapulmonary manifestations of SARS-CoV-2 infection., PMID:37040185
Zinc fingers and homeoboxes 2 inhibition could suppress the proliferation of ovarian cancer cells by apoptosis pathway., PMID:36746874
ZHX2 in health and disease., PMID:36465389
Zinc Fingers and Homeobox Family in Cancer: A Double-Edged Sword., PMID:36232466
Investigating the genetic profile of familial atypical cystic fibrosis patients (DeltaF508-CFTR) with neonatal biliary atresia., PMID:36205856
Zinc fingers and homeoboxes 2 is required for diethylnitrosamine-induced liver tumor formation in C57BL/6 mice., PMID:36194180
Cystathionine β-synthase gene inactivation dysregulates major urinary protein biogenesis and impairs sexual signaling in mice., PMID:36098436
USP13 promotes deubiquitination of ZHX2 and tumorigenesis in kidney cancer., PMID:36037364
Zhx2 Is a Candidate Gene Underlying Oxymorphone Metabolite Brain Concentration Associated with State-Dependent Oxycodone Reward., PMID:35688478
Novel regulation of the transcription factor ZHX2 by N-terminal methylation., PMID:35613330
LINC01431 Promotes Histone H4R3 Methylation to Impede HBV Covalently Closed Circular DNA Transcription by Stabilizing PRMT1., PMID:35398991
ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14., PMID:35151335
Microarray Genotyping Identifies New Loci Associated with Dementia in Parkinson's Disease., PMID:34946922
ZHX2 promotes HIF1α oncogenic signaling in triple-negative breast cancer., PMID:34779768
The transcription factor zinc fingers and homeoboxes 2 alleviates NASH by transcriptional activation of phosphatase and tensin homolog., PMID:34545586
Transcription factor Zhx2 restricts NK cell maturation and suppresses their antitumor immunity., PMID:34279541
LncRNA PART1 Promotes Proliferation and Migration, Is Associated with Cancer Stem Cells, and Alters the miRNA Landscape in Triple-Negative Breast Cancer., PMID:34072264
Bioinformatic analysis linking genomic defects to chemosensitivity and mechanism of action., PMID:33909629
Upregulation of ZHX2 predicts poor prognosis and is correlated with immune infiltration in gastric cancer., PMID:33837660
Anti-TROVE2 Antibody Determined by Immune-Related Array May Serve as a Predictive Marker for Adalimumab Immunogenicity and Effectiveness in RA., PMID:33763493
HNRNPD interacts with ZHX2 regulating the vasculogenic mimicry formation of glioma cells via linc00707/miR-651-3p/SP2 axis., PMID:33542193
Low expression of ZHX1 and ZHX2 impacts on the prognosis of chronic lymphocytic leukemia., PMID:33541423
ZHX2 mediates proteasome inhibitor resistance via regulating nuclear translocation of NF-κB in multiple myeloma., PMID:32780537
Prognostic value and therapeutic implications of ZHX family member expression in human gastric cancer., PMID:32774706
ZHX2 inhibits SREBP1c-mediated de novo lipogenesis in hepatocellular carcinoma via miR-24-3p., PMID:32770671
ZHX2 drives cell growth and migration via activating MEK/ERK signal and induces Sunitinib resistance by regulating the autophagy in clear cell Renal Cell Carcinoma., PMID:32382017
Zhx2 Accelerates Sepsis by Promoting Macrophage Glycolysis via Pfkfb3., PMID:32179636
Chromatin structure regulates cancer-specific alternative splicing events in primary HPV-related oropharyngeal squamous cell carcinoma., PMID:32164487
Evolutionary Analysis of the Zinc Finger and Homeoboxes Family of Proteins Identifies Multiple Conserved Domains and a Common Early Chordate Ancestor., PMID:32125369
ZHX2 restricts hepatocellular carcinoma by suppressing stem cell-like traits through KDM2A-mediated H3K36 demethylation., PMID:32114388
The zinc fingers and homeoboxes 2 protein ZHX2 and its interacting proteins regulate upstream pathways in podocyte diseases., PMID:32059999
Tumor suppressor ZHX2 inhibits NAFLD-HCC progression via blocking LPL-mediated lipid uptake., PMID:31740790
For research use only. Not for human or drug use.
