OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy. PMID: 36113464
Nuclear Gene-Encoded Leigh Syndrome Spectrum Overview. PMID: 26425749
COX10 codes for a protein homologous to the ORF1 product of Paracoccus denitrificans and is required for the synthesis of yeast cytochrome oxidase. PMID: 2167310
Adrenergic nerves activate an angio-metabolic switch in prostate cancer. PMID: 29051371
Coupled analysis of transcriptome and BCR mutations reveals role of OXPHOS in affinity maturation. PMID: 34031613
Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. PMID: 32080200
Knockdown of NCK1-AS1 inhibits the development of atherosclerosis by targeting miR-1197/COX10 axis. PMID: 34986861
COX10-AS1 Facilitates Cell Proliferation and Inhibits Cell Apoptosis in Glioblastoma Cells at Post-Transcription Level. PMID: 32770454
Reliance on Cox10 and oxidative metabolism for antigen-specific NK cell expansion. PMID: 34077722
Salidroside attenuates CoCl2-simulated hypoxia injury in PC12 cells partly by mitochondrial protection. PMID: 34748770
Long non coding RNA COX10-DT promotes the progression of breast cancer via the COX10-DT/miR-206/BDNF axis. PMID: 36463760
COX10 mutations resulting in complex multisystem mitochondrial disease that remains stable into adulthood. PMID: 24100867
A Novel COX10 Deletion Polymorphism as a Susceptibility Factor for Sudden Cardiac Death Risk in Chinese Populations. PMID: 33180568
Integrative Proteomics and Phosphoproteomics Profiling Reveals Dynamic Signaling Networks and Bioenergetics Pathways Underlying T Cell Activation. PMID: 28285833
RNA-sequencing reveals that STRN, ZNF484 and WNK1 add to the value of mitochondrial MT-COI and COX10 as markers of unstable coronary artery disease. PMID: 31821324
The role of Coa2 in hemylation of yeast Cox1 revealed by its genetic interaction with Cox10. PMID: 19841065
Oligomerization of heme o synthase in cytochrome oxidase biogenesis is mediated by cytochrome oxidase assembly factor Coa2. PMID: 22669974
Human mitochondrial protein complexes revealed by large-scale coevolution analysis and deep learning-based structure modeling. PMID: 35881696
Hypoxia Promotes Mitochondrial Complex I Abundance via HIF-1α in Complex III and Complex IV Eficient Cells. PMID: 33003371
Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 Axis. PMID: 33013423
The human COX10 gene is disrupted during homologous recombination between the 24 kb proximal and distal CMT1A-REPs. PMID: 9285799
Destabilizing COXIV in Müller Glia Increases Retinal Glycolysis and Alters Scotopic Electroretinogram. PMID: 36497016
Deficient mitochondrial respiration in astrocytes impairs trace fear conditioning and increases naloxone-precipitated aversion in morphine-dependent mice. PMID: 35275429
Mice lacking COX10 in skeletal muscle recapitulate the phenotype of progressive mitochondrial myopathies associated with cytochrome c oxidase deficiency. PMID: 16103131
Isolation of a human cDNA for heme A:farnesyltransferase by functional complementation of a yeast cox10 mutant. PMID: 8078902
Rhodiola crenulata attenuates apoptosis and mitochondrial energy metabolism disorder in rats with hypobaric hypoxia-induced brain injury by regulating the HIF-1α/microRNA 210/ISCU1/2(COX10) signaling pathway. PMID: 30878546
Mutations in COX10 result in a defect in mitochondrial heme A biosynthesis and account for multiple, early-onset clinical phenotypes associated with isolated COX deficiency. PMID: 12928484
Genomic structure and expression of the human heme A:farnesyltransferase (COX10) gene. PMID: 9177788
Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression. PMID: 20498629
Polygenetic Variants Related to Osteoarthritis Risk and Their Interactions with Energy, Protein, Fat, and Alcohol Intake in Adults in a Large Cohort. PMID: 35204431
[A case with cytochrome C oxidase deficiency caused by COX10 gene variation]. PMID: 34405646
[Expression of COX10 in human non-obstructive azoospermia testes]. PMID: 19694371
Mitochondrial dysfunction induces ALK5-SMAD2-mediated hypovascularization and arteriovenous malformations in mouse retinas. PMID: 36496409
Human cytochrome oxidase deficiency. PMID: 11044474
Screening and Characterization of a Non-cyp51A Mutation in an Aspergillus fumigatus cox10 Strain Conferring Azole Resistance. PMID: 27799210
Nuclear factors: roles related to mitochondrial deafness. PMID: 23510774
Regulation of gene expression by miR-144/451 during mouse erythropoiesis. PMID: 30971389
Cytochrome c oxidase deficiency. PMID: 11579424
Cytochrome c oxidase biogenesis in a patient with a mutation in COX10 gene. PMID: 15455402
On the functions of the yeast COX10 and COX11 gene products. PMID: 8118433
Energy deficit in parvalbumin neurons leads to circuit dysfunction, impaired sensory gating and social disability. PMID: 27105708
The Charcot-Marie-Tooth binary repeat contains a gene transcribed from the opposite strand of a partially duplicated region of the COX10 gene. PMID: 9403059
Nuclear expression of mitochondrial ND4 leads to the protein assembling in complex I and prevents optic atrophy and visual loss. PMID: 26029714
Sideroblastic anemia associated with multisystem mitochondrial disorders. PMID: 30588737
Cytochrome c oxidase subassemblies in fibroblast cultures from patients carrying mutations in COX10, SCO1, or SURF1. PMID: 14607829
Cytochrome oxidase assembly in yeast requires the product of COX11, a homolog of the P. denitrificans protein encoded by ORF3. PMID: 2167832
Genetic defects of cytochrome c oxidase assembly. PMID: 15119951
A defect in the mitochondrial complex III, but not complex IV, triggers early ROS-dependent damage in defined brain regions. PMID: 22914734
Mutations in respiratory chain complexes and human diseases. PMID: 15356960
Enhanced protein export in Saccharomyces cerevisiae nud1 mutants is an active process. PMID: 17072669
Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth. PMID: 32694534
Defects in mitochondrial respiratory complexes III and IV, and human pathologies. PMID: 12231008
A mutation in the human heme A:farnesyltransferase gene (COX10 ) causes cytochrome c oxidase deficiency. PMID: 10767350
Analysis of Leigh syndrome mutations in the yeast SURF1 homolog reveals a new member of the cytochrome oxidase assembly factor family. PMID: 20624914
Biosynthesis and functional role of haem O and haem A. PMID: 7885224
Enhanced glycolysis and GSK3 inactivation promote brain metabolic adaptations following neuronal mitochondrial stress. PMID: 34559217
Integrated Bioinformatics Analysis of the Hub Genes Involved in Irinotecan Resistance in Colorectal Cancer. PMID: 35885025
Suppression of mitochondrial electron transport chain function in the hypoxic human placenta: a role for miRNA-210 and protein synthesis inhibition. PMID: 23383105
Homeostasis and transitional activation of regulatory T cells require c-Myc. PMID: 31911938
AtCOX10, a protein involved in haem o synthesis during cytochrome c oxidase biogenesis, is essential for plant embryogenesis and modulates the progression of senescence. PMID: 26246612
[mRNA localization to the mitochondrial surface: a tool to treat retinal pathologies due to mitochondrial DNA mutations]. PMID: 17762826
Cytochrome c oxidase is required for the assembly/stability of respiratory complex I in mouse fibroblasts. PMID: 16782876
The Organization of Mitochondrial Supercomplexes is Modulated by Oxidative Stress In Vivo in Mouse Models of Mitochondrial Encephalopathy. PMID: 29861458
Defects in the biosynthesis of mitochondrial heme c and heme a in yeast and mammals. PMID: 15576047
Respiration-Deficient Astrocytes Survive As Glycolytic Cells In Vivo. PMID: 28314814
Long Range Endocrine Delivery of Circulating miR-210 to Endothelium Promotes Pulmonary Hypertension. PMID: 32493166
Loss of LRPPRC causes ATP synthase deficiency. PMID: 24399447
A CMC1-knockout reveals translation-independent control of human mitochondrial complex IV biogenesis. PMID: 28082314
Pbp1, the yeast ortholog of human Ataxin-2, functions in the cell growth on non-fermentable carbon sources. PMID: 33984024
Identification of acetic acid sensitive strains through biosensor-based screening of a Saccharomyces cerevisiae CRISPRi library. PMID: 36243715
Incorporating founder virus information in vaccine field trials. PMID: 25773491
Leigh Syndrome: Spectrum of Molecular Defects and Clinical Features in Russia. PMID: 36675121
Defective mitochondrial translation caused by a ribosomal protein (MRPS16) mutation. PMID: 15505824
Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity. PMID: 22622581
Regulation of the heme A biosynthetic pathway: differential regulation of heme A synthase and heme O synthase in Saccharomyces cerevisiae. PMID: 18953022
Mouse models of oxidative phosphorylation dysfunction and disease. PMID: 18848991
Intersection of Race/Ethnicity and Socioeconomic Status in Mortality After Breast Cancer. PMID: 26072260
Photobiomodulation enhancement of cell proliferation at 660 nm does not require cytochrome c oxidase. PMID: 30927704
Effect of bezafibrate treatment on late-onset mitochondrial myopathy in mice. PMID: 22012983
Identification of B cells participated in the mechanism of postmenopausal women osteoporosis using microarray analysis. PMID: 25785089
Genetic association of the cytochrome c oxidase-related genes with Alzheimer's disease in Han Chinese. PMID: 30054583
Sustained AMPK activation improves muscle function in a mitochondrial myopathy mouse model by promoting muscle fiber regeneration. PMID: 27288451
BcRISP1, isolated from non-heading Chinese cabbage, decreases the seed set of transgenic Arabidopsis. PMID: 26504557
Deletion of the Mitochondrial Complex-IV Cofactor Heme A:Farnesyltransferase Causes Focal Segmental Glomerulosclerosis and Interferon Response. PMID: 30268775
Screening and characterization of long noncoding RNAs involved in the albinism of Ananas comosus var. bracteatus leaves. PMID: 31756232
Endurance exercise is protective for mice with mitochondrial myopathy. PMID: 19286571
Analysis of Oligomerization Properties of Heme a Synthase Provides Insights into Its Function in Eukaryotes. PMID: 26940873
Pathophysiology and fate of hepatocytes in a mouse model of mitochondrial hepatopathies. PMID: 17951359
Expression of the alternative oxidase complements cytochrome c oxidase deficiency in human cells. PMID: 20049701
Genetic determinants of mitochondrial response to arsenic in yeast Saccharomyces cerevisiae. PMID: 17942904
Regulation of the heme A biosynthetic pathway in Saccharomyces cerevisiae. PMID: 11959116
A Targeted Mutation Disrupting Mitochondrial Complex IV Function in Primary Afferent Neurons Leads to Pain Hypersensitivity Through P2Y1 Receptor Activation. PMID: 30689196
Heme A synthesis and CcO activity are essential for Trypanosoma cruzi infectivity and replication. PMID: 28588043
RETRACTED: Bezafibrate improves mitochondrial function in the CNS of a mouse model of mitochondrial encephalopathy. PMID: 23261681
A new old yellow enzyme of Saccharomyces cerevisiae. PMID: 7836424
Comparative Genomics and Characterisation of the Role of Saccharomyces cerevisiae Respiration in the Fermentation of Chinese Steamed Bread., PMID:39997408
Integrated TWAS, GWAS, and RNAseq results identify candidate genes associated with reproductive traits in cows., PMID:39809816
Tissue-specific adaptations to cytochrome c oxidase deficiency shape physiological outcomes., PMID:39613003
Identifying Hub Genes and Metabolic Pathways in Collagen VI-Related Dystrophies: A Roadmap to Therapeutic Intervention., PMID:39595553
Restoration of defective oxidative phosphorylation to a subset of neurons prevents mitochondrial encephalopathy., PMID:39169163
Phenotypic assessment of Cox10 variants and their implications for Leigh Syndrome., PMID:39152498
Opa1 processing is dispensable in mouse development but is protective in mitochondrial cardiomyopathy., PMID:39093974
Translatomics reveals the role of dietary calcium addition in regulating muscle fat deposition in pigs., PMID:38811812
Mild therapeutic hypothermia upregulates the O-GlcNAcylation level of COX10 to alleviate mitochondrial damage induced by myocardial ischemia-reperfusion injury., PMID:38778315
Long Non-coding RNA COX10-AS1 Promotes Glioma Progression by Competitively Binding miR-1-3p to Regulate ORC6 Expression., PMID:38244670
Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes., PMID:38123683
Role of mitochondrial farnesyltransferase gene in the prevention of the food spoilage fungi Aspergillus flavus by the antimicrobial natural preservative perillaldehyde., PMID:38049276
Leigh Syndrome: Spectrum of Molecular Defects and Clinical Features in Russia., PMID:36675121
Destabilizing COXIV in Müller Glia Increases Retinal Glycolysis and Alters Scotopic Electroretinogram., PMID:36497016
Mitochondrial dysfunction induces ALK5-SMAD2-mediated hypovascularization and arteriovenous malformations in mouse retinas., PMID:36496409
Long non coding RNA COX10-DT promotes the progression of breast cancer via the COX10-DT/miR-206/BDNF axis., PMID:36463760
Identification of acetic acid sensitive strains through biosensor-based screening of a Saccharomyces cerevisiae CRISPRi library., PMID:36243715
OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy., PMID:36113464
Integrated Bioinformatics Analysis of the Hub Genes Involved in Irinotecan Resistance in Colorectal Cancer., PMID:35885025
Human mitochondrial protein complexes revealed by large-scale coevolution analysis and deep learning-based structure modeling., PMID:35881696
Protective Effect of Brassica rapa Polysaccharide against Acute High-Altitude Hypoxia-Induced Brain Injury and Its Metabolomics., PMID:39282147
Deficient mitochondrial respiration in astrocytes impairs trace fear conditioning and increases naloxone-precipitated aversion in morphine-dependent mice., PMID:35275429
Polygenetic Variants Related to Osteoarthritis Risk and Their Interactions with Energy, Protein, Fat, and Alcohol Intake in Adults in a Large Cohort., PMID:35204431
Knockdown of NCK1-AS1 inhibits the development of atherosclerosis by targeting miR-1197/COX10 axis., PMID:34986861
Salidroside attenuates CoCl2-simulated hypoxia injury in PC12 cells partly by mitochondrial protection., PMID:34748770
Enhanced glycolysis and GSK3 inactivation promote brain metabolic adaptations following neuronal mitochondrial stress., PMID:34559217
[A case with cytochrome C oxidase deficiency caused by COX10 gene variation]., PMID:34405646
Reliance on Cox10 and oxidative metabolism for antigen-specific NK cell expansion., PMID:34077722
Coupled analysis of transcriptome and BCR mutations reveals role of OXPHOS in affinity maturation., PMID:34031613
Pbp1, the yeast ortholog of human Ataxin-2, functions in the cell growth on non-fermentable carbon sources., PMID:33984024
A Novel COX10 Deletion Polymorphism as a Susceptibility Factor for Sudden Cardiac Death Risk in Chinese Populations., PMID:33180568
Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 Axis., PMID:33013423
Hypoxia Promotes Mitochondrial Complex I Abundance via HIF-1α in Complex III and Complex IV Eficient Cells., PMID:33003371
COX10-AS1 Facilitates Cell Proliferation and Inhibits Cell Apoptosis in Glioblastoma Cells at Post-Transcription Level., PMID:32770454
Age-dependent assessment of genes involved in cellular senescence, telomere and mitochondrial pathways in human lung tissue of smokers, COPD and IPF: Associations with SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 axis., PMID:32702724
Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth., PMID:32694534
Age-dependent assessment of genes involved in cellular senescence, telomere and mitochondrial pathways in human lung tissue of smokers, COPD and IPF: Associations with SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 axis., PMID:32587985
Long Range Endocrine Delivery of Circulating miR-210 to Endothelium Promotes Pulmonary Hypertension., PMID:32493166
Identification of Long Noncoding RNAs as Predictors of Survival in Triple-Negative Breast Cancer Based on Network Analysis., PMID:32190687
Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency., PMID:32080200
Homeostasis and transitional activation of regulatory T cells require c-Myc., PMID:31911938
RNA-sequencing reveals that STRN, ZNF484 and WNK1 add to the value of mitochondrial MT-COI and COX10 as markers of unstable coronary artery disease., PMID:31821324
Screening and characterization of long noncoding RNAs involved in the albinism of Ananas comosus var. bracteatus leaves., PMID:31756232
Regulation of gene expression by miR-144/451 during mouse erythropoiesis., PMID:30971389
Photobiomodulation enhancement of cell proliferation at 660 nm does not require cytochrome c oxidase., PMID:30927704
Congenital cochlear deafness in mitochondrial diseases related to RRM2B and SERAC1 gene defects. A study of the mitochondrial patients of the CMHI hospital in Warsaw, Poland., PMID:30909120
Rhodiola crenulata attenuates apoptosis and mitochondrial energy metabolism disorder in rats with hypobaric hypoxia-induced brain injury by regulating the HIF-1α/microRNA 210/ISCU1/2(COX10) signaling pathway., PMID:30878546
A Targeted Mutation Disrupting Mitochondrial Complex IV Function in Primary Afferent Neurons Leads to Pain Hypersensitivity Through P2Y1 Receptor Activation., PMID:30689196
Sideroblastic anemia associated with multisystem mitochondrial disorders., PMID:30588737
For research use only. Not for human or drug use.
