Catalog No.
YHF86802
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu30-Glu175
Predicted molecular weight
28.73 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q01449
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MYLC2A, Myosin regulatory light chain 7, MLC-2a, Myosin light chain 2a, MYL7, MYL2A, MLC2a, Myosin regulatory light chain 2, atrial isoform
Vasorin deficiency leads to cardiac hypertrophy by targeting MYL7 in young mice. PMID: 34854218
Development of Tg(UAS:SEC-Hsa.ANXA5-YFP,myl7:RFP); Casper(roy-/-,nacre-/-) Transparent Transgenic In Vivo Zebrafish Model to Study the Cardiomyocyte Function. PMID: 34440732
Early calcium and cardiac contraction defects in a model of phospholamban R9C mutation in zebrafish. PMID: 36273660
l-selenomethionine induces zebrafish embryo cardiovascular defects via down-regulating expression of lrp2b. PMID: 34933029
Cardiotoxicity of Zebrafish Induced by 6-Benzylaminopurine Exposure and Its Mechanism. PMID: 35955574
HiPS-Endothelial Cells Acquire Cardiac Endothelial Phenotype in Co-culture With hiPS-Cardiomyocytes. PMID: 34422835
Fluorescent Gene Tagging of Transcriptionally Silent Genes in hiPSCs. PMID: 30956114
Antithrombin, PC (Protein C), and PS (Protein S): Genome and Transcriptome-Wide Association Studies Identify 7 Novel Loci Regulating Plasma Levels. PMID: 37128921
Optimized Aequorin Reconstitution Protocol to Visualize Calcium Ion Transients in the Heart of Transgenic Zebrafish Embryos In Vivo. PMID: 35821478
Heat-shock-induced tyrosinase gene ablation with CRISPR in zebrafish. PMID: 32367255
Zebrafish ambra1a and ambra1b Silencing Affect Heart Development. PMID: 32320344
Proteomic analysis of human fetal atria and ventricle. PMID: 25323733
Fenbuconazole exposure impacts the development of zebrafish embryos. PMID: 29715634
Bioinformatics Analysis of Genes and Mechanisms in Postherpetic Neuralgia. PMID: 33029266
The role of cldnh during the early retinal development in zebrafish. PMID: 32866532
Gene Expression Profiles at Different Time Points after Acute Myocardial Infarction in Mice. PMID: 36221828
Titin-truncating mutations associated with dilated cardiomyopathy alter length-dependent activation and its modulation via phosphorylation. PMID: 33135063
[Joint regulation of Wnt and bone morphogenetic protein signaling pathways to promote differentiation of human induced pluripotent stem cells into cardiomyocytes]. PMID: 33063499
Increased circulating uric acid aggravates heart failure via impaired fatty acid metabolism. PMID: 36927819
sox9b is required in cardiomyocytes for cardiac morphogenesis and function. PMID: 30224706
Cardiotoxicity of forchlorfenuron (CPPU) in zebrafish (Danio rerio) and H9c2 cardiomyocytes. PMID: 31255755
Encapsulation of rat cardiomyoblasts with alginate-gelatin microspheres preserves stemness feature in vitro. PMID: 30399575
Evaluation of the increase of the thymoquinone permeability formulated in polymeric micelles: In vitro test and in vivo toxicity assessment in Zebrafish embryos. PMID: 34864170
The effects of kisspeptin-10 on serum metabolism and myocardium in rats. PMID: 28692647
Sensitivity to dioxin decreases as zebrafish mature. PMID: 22403156
[Generation of tnnt2a knock-out zebrafish via CRISPR/Cas9 and phenotypic analysis]. PMID: 28638918
Cardiovascular toxicity and anxiety-like behavior induced by deltamethrin in zebrafish (Danio rerio) larvae. PMID: 30537588
Mitigation of arsenic induced developmental cardiotoxicity by ferulic acid in zebrafish. PMID: 33631344
Developmental toxicity of Clerodendrum cyrtophyllum turcz ethanol extract in zebrafish embryo. PMID: 33144170
Smad4 is required for the development of cardiac and skeletal muscle in zebrafish. PMID: 27477184
Myocardium and BMP signaling are required for endocardial differentiation. PMID: 26092845
Exposure to acrylamide induces cardiac developmental toxicity in zebrafish during cardiogenesis. PMID: 29223822
Genomic and physiological analyses of the zebrafish atrioventricular canal reveal molecular building blocks of the secondary pacemaker region. PMID: 34557935
NADPH oxidase 4 induces cardiac arrhythmic phenotype in zebrafish. PMID: 24962575
Multiplexing physical stimulation on single human induced pluripotent stem cell-derived cardiomyocytes for phenotype modulation. PMID: 33710972
RNA sequencing-based transcriptome profiling of cardiac tissue implicates novel putative disease mechanisms in FLNC-associated arrhythmogenic cardiomyopathy. PMID: 31843279
Low-level embryonic crude oil exposure disrupts ventricular ballooning and subsequent trabeculation in Pacific herring. PMID: 33823483
[Construction and assessment of heart-specific green fluorescence zebrafish line]. PMID: 23659942
Exploring the toxicity of a bismuth-asparagine coordination polymer on the early development of zebrafish embryos. PMID: 23260032
Human Cardiomyocytes Prior to Birth by Integration-Free Reprogramming of Amniotic Fluid Cells. PMID: 27465073
Pbx acts with Hand2 in early myocardial differentiation. PMID: 19607825
Combined treatment of melatonin and sodium tanshinone IIA sulfonate reduced the neurological and cardiovascular toxicity induced by deltamethrin in zebrafish. PMID: 31765895
Toxicity assessment of combined fluoroquinolone and tetracycline exposure in zebrafish (Danio rerio). PMID: 25504783
Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues. PMID: 31801634
Genetic interactions between chromosomes 11 and 18 contribute to airway hyperresponsiveness in mice. PMID: 22253740
Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway. PMID: 24648383
Depletion of zebrafish essential and regulatory myosin light chains reduces cardiac function through distinct mechanisms. PMID: 18343897
Mef2cb regulates late myocardial cell addition from a second heart field-like population of progenitors in zebrafish. PMID: 21466801
Promotion of cardiac differentiation of brown adipose derived stem cells by chitosan hydrogel for repair after myocardial infarction. PMID: 24508080
Generation of cardiomyocytes from human-induced pluripotent stem cells resembling atrial cells with ability to respond to adrenoceptor agonists. PMID: 37122218
Restricted expression of cardiac myosin genes reveals regulated aspects of heart tube assembly in zebrafish. PMID: 10491254
Methylation of MYLK3 gene promoter region: a biomarker to stratify surgical care in ovarian cancer in a multicentre study. PMID: 28350786
Analysis of altered gene expression specific to embryotoxic chemical treatment during embryonic stem cell differentiation into myocardiac and neural cells. PMID: 22008533