Catalog No.
YHC98502
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln21-Val210
Predicted molecular weight
23.51 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P13591
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NCAM-1, NCAM1, CD56, N-CAM-1, NCAM, Neural cell adhesion molecule 1
NCAM1 (CD56) promotes leukemogenesis and confers drug resistance in AML. PMID: 30814062
Autoantibodies against NCAM1 from patients with schizophrenia cause schizophrenia-related behavior and changes in synapses in mice. PMID: 35492247
Schwann cells induce cancer cell dispersion and invasion. PMID: 26999607
NCAM1 Polysialylation: The Prion Protein's Elusive Reason for Being? PMID: 27879349
NCAM1 and GDF15 are biomarkers of Charcot-Marie-Tooth disease in patients and mice. PMID: 35148379
Natural Killer Cells Generated From Human Induced Pluripotent Stem Cells Mature to CD56brightCD16+NKp80+/-In-Vitro and Express KIR2DL2/DL3 and KIR3DL1. PMID: 34017328
The 140-kD isoform of CD56 (NCAM1) directs the molecular pathogenesis of ischemic cardiomyopathy. PMID: 23462508
Pro-Inflammatory S100A9 Protein Aggregation Promoted by NCAM1 Peptide Constructs. PMID: 31194501
NCAM1 is the Target of miRNA-572: Validation in the Human Oligodendroglial Cell Line. PMID: 28332001
Generation of highly proliferative, rejuvenated cytotoxic T cell clones through pluripotency reprogramming for adoptive immunotherapy. PMID: 34023508
The engineered peptide construct NCAM1-Aβ inhibits fibrillization of the human prion protein (PrP). PMID: 35143147
Human NK cells responses are enhanced by CD56 engagement. PMID: 35775327
Identification of a peptide targeting CD56. PMID: 32747027
Redefining CD56 as a Biomarker and Therapeutic Target in Multiple Myeloma. PMID: 35380709
Upregulation of Neural Cell Adhesion Molecule 1 (NCAM1) by hsa-miR-141-3p Suppresses Ameloblastoma Cell Migration. PMID: 32269209
Role of CD56 in Normal Kidney Development and Wilms Tumorigenesis. PMID: 27935326
Evaluation of CITED1, SIX1, and CD56 protein expression for identification of blastemal elements in Wilms tumor. PMID: 24838327
CD56 is Expressed in Uterine Smooth Muscle Tumors. PMID: 32897962
CD4(+)/CD56(+) hematodermic neoplasm. PMID: 21382786
Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo. PMID: 33548223
The association between NCAM1 levels and behavioral phenotypes in children with autism spectrum disorder. PMID: 30423390
TGF-β1 affects cell-cell adhesion in the heart in an NCAM1-dependent mechanism. PMID: 28870505
The Increased Ratio of Blood CD56bright NK to CD56dim NK Is a Distinguishing Feature of Primary Sjögren's Syndrome. PMID: 32695834
Prognostic significance of CD56 expression in patients with multiple myeloma: a meta-analysis. PMID: 35068378
A ZIP6-ZIP10 heteromer controls NCAM1 phosphorylation and integration into focal adhesion complexes during epithelial-to-mesenchymal transition. PMID: 28098160
Diagnostic value of CD56 immunohistochemistry in thyroid lesions. PMID: 29799356
Characterization of human natural killer cells for therapeutic use. PMID: 30910383
IL-17 production by NKG2D-expressing CD56+ T cells in type 2 diabetes. PMID: 30576948
siRNA-mediated NCAM1 gene silencing suppresses oxidative stress in pre-eclampsia by inhibiting the p38MAPK signaling pathway. PMID: 31353686
CD56 expression in benign and malignant thyroid lesions. PMID: 30173227
Expression of novel neuroendocrine marker insulinoma-associated protein 1 (INSM1) in genitourinary high-grade neuroendocrine carcinomas: An immunohistochemical study with specificity analysis and comparison to chromogranin, synaptophysin, and CD56. PMID: 32381384
Natural killer cells protect white matter integrity in bipolar disorder. PMID: 31254622
Peripheral lymphocyte subset alterations in COVID-19 patients. PMID: 32608572
A functional SNP rs895819 on pre-miR-27a is associated with bipolar disorder by targeting NCAM1. PMID: 35379867
Insulinoma-associated Protein 1 (INSM1) in Thoracic Tumors is Less Sensitive but More Specific Compared With Synaptophysin, Chromogranin A, and CD56. PMID: 30358615
Flow cytometric detection and quantification of CD56 (neural cell adhesion molecule, NCAM) expression in diffuse large B cell lymphomas and review of the literature. PMID: 22276608
NCAM1 supports therapy resistance and LSC function in AML. PMID: 31122937
EXT1 and NCAM1-associated membranous lupus nephritis in a cohort of patients undergoing repeat kidney biopsies. PMID: 35278072
CD56+ angioimmunoblastic T-cell lymphoma with evans syndrome : a case report and review of the literature. PMID: 23801132
CD56+ T cells inhibit HIV-1 infection of macrophages. PMID: 22591692
[Gangliocytic paragangliomas: a clinicopathologic study]. PMID: 30522176
NCAM1-TTC12-ANKK1-DRD2 variants and smoking motives as intermediate phenotypes for nicotine dependence. PMID: 25273375
Aberrant myelomonocytic CD56 expression in Down syndrome is frequent and not associated with leukemogenesis. PMID: 33890142
NCAM1 association study of bipolar disorder and schizophrenia: polymorphisms and alternatively spliced isoforms lead to similarities and differences. PMID: 17413444
CD56 Is a Pathogen Recognition Receptor on Human Natural Killer Cells. PMID: 28733594
Poikilodermatous mycosis fungoides with a CD8+ CD56+ immunophenotype: a case report and literature review. PMID: 23241021
Antitumor activity of CD56-chimeric antigen receptor T cells in neuroblastoma and SCLC models. PMID: 29622795
Clinical Significance of CD200 and CD56 Expression in Patients with Acute Myeloid Leukemia. PMID: 32212802
CD56 positive diffuse large B-cell lymphoma: a case report and literature review. PMID: 24294395
Expression of CD56 in patients with adenomyosis and its correlation with dysmenorrhea. PMID: 26344352
[THE TECHNQUE OF FLOW CYTOMETRY IN EVALUATION OF NK-CELLS AND THEIR ACTIVITY]. PMID: 26999864
Rapid Turnover of Cortical NCAM1 Regulates Synaptic Reorganization after Peripheral Nerve Injury. PMID: 29346771
Application of INSM1 in Diagnosis and Grading of Laryngeal Neuroendocrine Carcinoma. PMID: 33847383
[Epithelial neuroendocrine tumors of the upper respiratory tract: New entities, new perspectives]. PMID: 25963713
CD56brightCD16- natural killer cells are shifted toward an IFN-γ-promoting phenotype with reduced regulatory capacity in osteoarthritis. PMID: 31326139
Primary Plasma Cell Leukaemia: Case report and review of the literature. PMID: 30607287
Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis. PMID: 33045259
Role of CD56-expressing immature biliary epithelial cells in biliary atresia. PMID: 26937142
Primary gastric small cell carcinoma. PMID: 28363459
Targeted therapy aimed at cancer stem cells: Wilms' tumor as an example. PMID: 23760992
Direct involvement of CD56 in cytokine-induced killer-mediated lysis of CD56+ hematopoietic target cells. PMID: 25201755
Interpreting CD56+ and CD163+ infiltrates in early versus late renal transplant biopsies. PMID: 26087825
Antibody-dependent CD56+ T cell responses are functionally impaired in long-term HIV-1 infection. PMID: 27814766
CD27 engagement by a soluble CD70 protein enhances non-cytolytic antiviral activity of CD56bright natural killer cells by IFN-γ secretion. PMID: 24211844
Expression of neuroendocrine markers in non-neuroendocrine endometrial carcinomas. PMID: 31040050
[Immunophenotypic Analysis of Patients with CD56⁺ Acute Myeloid Leukemia]. PMID: 26524014
No genetic association between NCAM1 gene polymorphisms and schizophrenia in the Chinese population. PMID: 18601968
Prognostic impact of CD200 and CD56 expression in adult acute lymphoblastic leukemia patients. PMID: 29161980
Specific phenotype and function of CD56-expressing innate immune cell subsets in human thymus. PMID: 27354408
Insulinoma-associated Protein 1 (INSM1) Is a Better Marker for the Diagnosis and Prognosis Estimation of Small Cell Lung Carcinoma Than Neuroendocrine Phenotype Markers Such as Chromogranin A, Synaptophysin, and CD56. PMID: 32118626
CD56 antibody: old-fashioned or still trendy in endocrine lung tumors. PMID: 25140506
Increased ILT2 expression contributes to dysfunction of CD56dimCD16+NK cells in chronic hepatitis B virus infection. PMID: 35917968
Upregulation of KLK8 contributes to CUMS-induced hippocampal neuronal apoptosis by cleaving NCAM1. PMID: 37076499
Proteome analysis of human CD56neg NK cells reveals a homogeneous phenotype surprisingly similar to CD56dim NK cells. PMID: 29999523
Reactivation of NCAM1 defines a subpopulation of human adult kidney epithelial cells with clonogenic and stem/progenitor properties. PMID: 24055371
Expression and functional analysis of genes deregulated in mouse placental overgrowth models: Car2 and Ncam1. PMID: 16247769
CD56-negative NK cells with impaired effector function expand in CMV and EBV co-infected healthy donors with age. PMID: 30686790
Periocular Rash in a Healthy Teenager. PMID: 27078620
Natural killer cell-triggered vascular transformation: maternal care before birth? PMID: 20711229
Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor. PMID: 32753727
CD56+ T cells are increased in kidney transplant patients following cytomegalovirus infection. PMID: 26039898
An esophageal collision tumor. PMID: 23962544
Proteome analysis of distinct developmental stages of human natural killer (NK) cells. PMID: 23315794
Ectopic thyroid in left parotid gland with an orthotopic thyroid gland: A rare case scenario. PMID: 34673603
High expression of CD56 may be associated with favorable overall survival in intermediate-risk acute myeloid leukemia. PMID: 33594945
CD56 (NCAM) expression in ameloblastomas and other odontogenic lesions. PMID: 20875069
CD56 Expression Is an Important Prognostic Factor in Multiple Myeloma Even with Bortezomib Induction. PMID: 29920491
The osteogenic commitment of CD271+CD56+ bone marrow stromal cells (BMSCs) in osteoarthritic femoral head bone. PMID: 32636407
Protein microarray analysis identifies key cytokines associated with malignant middle cerebral artery infarction. PMID: 28828208
CD8+ CD56+ mycosis fungoides with an indolent clinical behaviour: case report and literature review. PMID: 20814634
Evolutionary conserved role of neural cell adhesion molecule-1 in memory. PMID: 32632143
AbroGATAed human NK cell development. PMID: 23557967
For research use only. Not for human or drug use.
