Catalog No.
YHK90101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg356-Gly420
Predicted molecular weight
36.15 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9P0W8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HSD3, Spermatogenesis-associated protein HSD3, SPATA7, Spermatogenesis-associated protein 7, HSD-3.1
The spermatogenesis-associated protein-7 (SPATA7) gene - an overview. PMID: 32799588
Nonsyndromic Retinitis Pigmentosa Overview. PMID: 20301590
Spata7 is required for maintenance of the retinal connecting cilium. PMID: 35368022
Spata7 is a retinal ciliopathy gene critical for correct RPGRIP1 localization and protein trafficking in the retina. PMID: 25398945
Conditional loss of Spata7 in photoreceptors causes progressive retinal degeneration in mice. PMID: 29100828
Spectrum, frequency, and genotype-phenotype of mutations in SPATA7. PMID: 31908400
Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies. PMID: 25965394
AAV8(Y733F)-mediated gene therapy in a Spata7 knockout mouse model of Leber congenital amaurosis and retinitis pigmentosa. PMID: 21310915
Screening of SPATA7 in patients with Leber congenital amaurosis and severe childhood-onset retinal dystrophy reveals disease-causing mutations. PMID: 29899041
SPATA7 maintains a novel photoreceptor-specific zone in the distal connecting cilium. PMID: 26854980
SPATA7: Evolving phenotype from cone-rod dystrophy to retinitis pigmentosa. PMID: 20104588
Spectrum of SPATA7 mutations in Leber congenital amaurosis and delineation of the associated phenotype. PMID: 29411205
Phenotypic expansion and progression of SPATA7-associated retinitis pigmentosa. PMID: 22219627
Lack of phenotypic effect of triallelic variation in SPATA7 in a family with Leber congenital amaurosis resulting from CRB1 mutations. PMID: 25814828
Novel homozygous large deletion including the 5' part of the SPATA7 gene in a consanguineous Israeli Muslim Arab family. PMID: 30285347
Leber Congenital Amaurosis / Early-Onset Severe Retinal Dystrophy Overview. PMID: 19268277
Mutations in SPATA7 cause Leber congenital amaurosis and juvenile retinitis pigmentosa. PMID: 33545363
Identification of Novel Serological Autoantibodies in Takayasu Arteritis Patients Using HuProt Arrays. PMID: 20301475
Leber Congenital Amaurosis – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY. PMID: 28966547
Diagnostic application of clinical exome sequencing in Leber congenital amaurosis. PMID: 37164434
SPATA7-Associated Juvenile Retinitis Pigmentosa in Two Brothers from a Consanguineous Iraqi Family in Switzerland. PMID: 32693775
Sub-fertility in crossbred bulls: deciphering testicular level transcriptomic alterations between zebu (Bos indicus) and crossbred (Bos taurus x Bos indicus) bulls. PMID: 28481129
Novel homozygous mutation in the SPATA7 gene causes autosomal recessive retinal degeneration in a consanguineous German family. PMID: 31406157
Targeted sequencing of linkage region in Dominican families implicates PRIMA1 and the SPATA7-PTPN21-ZC3H14-EML5-TTC8 locus in carotid-intima media thickness and atherosclerotic events. PMID: 22136677
Late onset retinitis pigmentosa. PMID: 36140798
Exome Sequencing Identified Molecular Determinants of Retinal Dystrophies in Nine Consanguineous Pakistani Families. PMID: 12736779
A novel gene, RSD-3/HSD-3.1, encodes a meiotic-related protein expressed in rat and human testis. PMID: 30647131
Deletion of both centrin 2 (CETN2) and CETN3 destabilizes the distal connecting cilium of mouse photoreceptors. PMID: 17823934
SRD5A2 and HSD3B2 polymorphisms are associated with prostate cancer risk and aggressiveness. PMID: 20056642
Genetic variation of genes involved in dihydrotestosterone metabolism and the risk of prostate cancer. PMID: 26147992
Homozygosity Mapping in Leber Congenital Amaurosis and Autosomal Recessive Retinitis Pigmentosa in South Indian Families. PMID: 18505908
For research use only. Not for human or drug use.
