Catalog No.
PHC13201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CYP11A1 (Met1-Gly300).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Cholesterol side-chain cleavage enzyme, mitochondrial, CYPXIA1, CYP11A, Cholesterol desmolase, Cytochrome P450 11A1, CYP11A1, Cytochrome P450(scc)
Purification
Purified by antigen affinity column.
Accession
P05108
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Advances in Targeted Therapy for Metastatic Prostate Cancer., PMID:40299225
Bimodal genomic approach predicting Semaphorin 7A (SEMA7A) as prognostic biomarker in adrenocortical carcinoma., PMID:40291702
The proteomic landscape of trophoblasts unravels calcium-dependent syncytialization processes and beta-chorionic gonadotropin (ß-hCG) production., PMID:40038668
Dihydroberberine alleviates Th17/Treg imbalance in premature ovarian insufficiency mice via inhibiting Rheb/mTOR signaling., PMID:39472803
Diagnostic Value of Autoantibodies against Steroidogenic Enzymes and Hormones in Infertile Women with Premature Ovarian Insufficiency., PMID:38928251
Microbiota modulates the steroid response to acute immune stress in male mice., PMID:38361932
Association of CYP11A1 Polymorphisms with Recurrent Pregnancy Loss in the Female Population of Punjab., PMID:38045509
P450 Side-Chain Cleavage Enzyme (P450-SCC) Is an Ovarian Autoantigen in a Mouse Model for Autoimmune Oophoritis., PMID:35585293
Cyp11a2 Is Essential for Oocyte Development and Spermatogonial Stem Cell Differentiation in Zebrafish., PMID:34932120
Synergistic Regulatory Effect of Inhibin and Anti-Müllerian Hormone on Fertility of Mice., PMID:34820437
20S-Hydroxyvitamin D3, a Secosteroid Produced in Humans, Is Anti-Inflammatory and Inhibits Murine Autoimmune Arthritis., PMID:34276665
Impairment of testes development in Yangzhou ganders by augmentation of leptin receptor signaling., PMID:34051590
The Gut Microbiota Affects Corticosterone Production in the Murine Small Intestine., PMID:33921780
Primary Ovarian Insufficiency in Women With Addison's Disease., PMID:33686417
Neurotrophin-3 stimulates stem Leydig cell proliferation during regeneration in rats., PMID:33090725
Noncalcemic Vitamin D Hydroxyderivatives Inhibit Human Oral Squamous Cell Carcinoma and Down-regulate Hedgehog and WNT/β-Catenin Pathways., PMID:32366390
Analysis of Corticosterone and Testosterone Synthesis in Rat Salivary Gland Homogenates., PMID:31379745
Icariin inhibits inflammation via immunomodulation of the cutaneous hypothalamus-pituitary-adrenal axis in vitro., PMID:30155911
A longitudinal study of autoantibodies against cytochrome P450 side-chain cleavage enzyme in dogs (Canis lupus familiaris) affected with hypoadrenocorticism (Addison's disease)., PMID:30078597
Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions., PMID:27422263
Autoantibodies against Cytochrome P450 Side-Chain Cleavage Enzyme in Dogs (Canis lupus familiaris) Affected with Hypoadrenocorticism (Addison's Disease)., PMID:26618927
Initiation of active immunization against testosterone during early puberty alters negative feedback regulation of the hypothalamic-pituitary-testicular axis in rabbits., PMID:24906938
Overexpression of a DENND1A isoform produces a polycystic ovary syndrome theca phenotype., PMID:24706793
Conductometric monitoring of protein-protein interactions., PMID:24106799
Testosterone implants modify the steroid hormone balance and the gonadal physiology of gilthead seabream (Sparus aurata L.) males., PMID:23743364
The increased number of Leydig cells by di(2-ethylhexyl) phthalate comes from the differentiation of stem cells into Leydig cell lineage in the adult rat testis., PMID:23391632
Research on the steroidogenesis of proliferated Leydig cells in vitro., PMID:23322215
Restart of steroidogenesis in dogs during recrudescence of testicular function following downregulation with a GnRH-agonist implant., PMID:23053053
Insulin-like growth factor 3 regulates expression of genes encoding steroidogenic enzymes and key transcription factors in the Nile tilapia gonad., PMID:22337331
Effects of kisspeptin-10 on progesterone secretion in cultured chicken ovarian granulosa cells from preovulatory (F1-F3) follicles., PMID:21924307
CREB coactivator CRTC2/TORC2 and its regulator calcineurin crucially mediate follicle-stimulating hormone and transforming growth factor β1 upregulation of steroidogenesis., PMID:21826657
Effect of brominated flame retardant BDE-47 on androgen production of adult rat Leydig cells., PMID:21704137
Premature ovarian failure in patients with autoimmune Addison's disease: clinical, genetic, and immunological evaluation., PMID:21677034
Development of steroid signaling pathways during primordial follicle formation in the human fetal ovary., PMID:21430025
Nuclear factor NF45 interacts with viral proteins of infectious bursal disease virus and inhibits viral replication., PMID:20702628
Autoantibody responses in autoimmune ovarian insufficiency and in Addison's disease are IgG1 dominated and suggest a predominant, but not exclusive, Th1 type of response., PMID:20498138
Congenital lipoid adrenal hyperplasia: functional characterization of three novel mutations in the STAR gene., PMID:20080861
Fetal testis dysgenesis and compromised Leydig cell function in Tgfbr3 (beta glycan) knockout mice., PMID:19696014
Neurosteroids and epileptogenesis in the pilocarpine model: evidence for a relationship between P450scc induction and length of the latent period., PMID:19125849
Identification of ERK and JNK as signaling mediators on protein kinase C activation in cultured granulosa cells., PMID:18694803
Inhibitory effects of cholesterol sulfate on progesterone production in human granulosa-like tumor cell line, KGN., PMID:18490834
Generation and utilization of P450 cholesterol side-chain cleavage enzyme and 3beta-hydroxysteroid dehydrogenase antibodies for universal detection., PMID:18360810
Immunolocalization of cholesterol side chain cleavage enzyme (P450scc) in Mytilus galloprovincialis and its induction by nutritional levels., PMID:18340451
Immunohistochemical identification of cells expressing steroidogenic enzymes cytochrome P450scc and P450 aromatase in taste buds of rat circumvallate papillae., PMID:18296822
Steroidogenic acute regulatory protein expression and pregnenolone synthesis in rat astrocyte cultures., PMID:17927664
Differentiation of adult stem cells derived from bone marrow stroma into Leydig or adrenocortical cells., PMID:16728492
Analysis of trophoblast giant cell steroidogenesis in primary cultures., PMID:16511989
Stimulatory effect of LH, PGE2 and progesterone on StAR protein, cytochrome P450 cholesterol side chain cleavage and 3beta hydroxysteroid dehydrogenase gene expression in bovine luteal cells., PMID:16303614
Changes in localization of cytochrome P450 cholesterol side-chain cleavage (P450scc) in Japanese eel testis and ovary during gonadal development., PMID:16168415
Tributyltin disturbs bovine adrenal steroidogenesis by two modes of action., PMID:16038956
For research use only. Not for human or drug use.
