Catalog No.
PHE26401
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human NNMT (Met1-Arg258).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Nicotinamide N-methyltransferase, NNMT
Purification
Purified by antigen affinity column.
Accession
P40261
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
NAD+ metabolism enzyme NNMT in cancer-associated fibroblasts drives tumor progression and resistance to immunotherapy by modulating macrophages in urothelial bladder cancer., PMID:39067875
Alterations in Kynurenine and NAD+ Salvage Pathways during the Successful Treatment of Inflammatory Bowel Disease Suggest HCAR3 and NNMT as Potential Drug Targets., PMID:34948292
Patients with low nicotinamide N-methyltransferase expression benefit significantly from bevacizumab treatment in ovarian cancer., PMID:33446144
The Rheumatoid Arthritis-Associated Citrullinome., PMID:29628436
Antisense oligonucleotide and thyroid hormone conjugates for obesity treatment., PMID:28839185
Role of Nicotinamide N-Methyltransferase in Dorsal Striatum in Cocaine Place Preference., PMID:28726800
Identification of specific biomarkers for gastric adenocarcinoma by ITRAQ proteomic approach., PMID:27941907
Expression profile and prognostic value of NNMT in patients with pancreatic cancer., PMID:26942567
Kidney transplants with progressing chronic diseases express high levels of acute kidney injury transcripts., PMID:23356967
Nicotinamide N-methyltransferase induces cellular invasion through activating matrix metalloproteinase-2 expression in clear cell renal cell carcinoma cells., PMID:21045016
Nicotinamide N-methyltransferase protein expression in renal cell cancer., PMID:20104648
Serum levels of nicotinamide N-methyltransferase in patients with lung cancer., PMID:19242722
Optimization of diagnostic ELISA-based tests for the detection of auto-antibodies against tumor antigens in human serum., PMID:18816257
Overexpression of nicotinamide N-methyltransferase in gastric cancer tissues and its potential post-translational modification., PMID:17079861
Identification of nicotinamide N-methyltransferase as a novel serum tumor marker for colorectal cancer., PMID:16166432
Activation of nicotinamide N-methyltransferase gene promoter by hepatocyte nuclear factor-1beta in human papillary thyroid cancer cells., PMID:15486044
Expression of nicotinamide N-methyltransferase (E.C. 2.1.1.1) in the Parkinsonian brain., PMID:11853016
Nicotinamide-N-methyltransferase is higher in the lumbar cerebrospinal fluid of patients with Parkinson's disease., PMID:11154840