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Anti-NNMT Polyclonal Antibody

Catalog #:   PHE26401 Specific References (18) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P40261
Overview

Catalog No.

PHE26401

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human NNMT (Met1-Arg258).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Nicotinamide N-methyltransferase, NNMT

Purification

Purified by antigen affinity column.

Accession

P40261

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with NNMT antibody (PHE26401) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 31 kDa
    Observed MW: 31 kDa
References

NAD+ metabolism enzyme NNMT in cancer-associated fibroblasts drives tumor progression and resistance to immunotherapy by modulating macrophages in urothelial bladder cancer., PMID:39067875

Alterations in Kynurenine and NAD+ Salvage Pathways during the Successful Treatment of Inflammatory Bowel Disease Suggest HCAR3 and NNMT as Potential Drug Targets., PMID:34948292

Patients with low nicotinamide N-methyltransferase expression benefit significantly from bevacizumab treatment in ovarian cancer., PMID:33446144

The Rheumatoid Arthritis-Associated Citrullinome., PMID:29628436

Antisense oligonucleotide and thyroid hormone conjugates for obesity treatment., PMID:28839185

Role of Nicotinamide N-Methyltransferase in Dorsal Striatum in Cocaine Place Preference., PMID:28726800

Identification of specific biomarkers for gastric adenocarcinoma by ITRAQ proteomic approach., PMID:27941907

Expression profile and prognostic value of NNMT in patients with pancreatic cancer., PMID:26942567

Kidney transplants with progressing chronic diseases express high levels of acute kidney injury transcripts., PMID:23356967

Nicotinamide N-methyltransferase induces cellular invasion through activating matrix metalloproteinase-2 expression in clear cell renal cell carcinoma cells., PMID:21045016

Nicotinamide N-methyltransferase protein expression in renal cell cancer., PMID:20104648

Serum levels of nicotinamide N-methyltransferase in patients with lung cancer., PMID:19242722

Optimization of diagnostic ELISA-based tests for the detection of auto-antibodies against tumor antigens in human serum., PMID:18816257

Overexpression of nicotinamide N-methyltransferase in gastric cancer tissues and its potential post-translational modification., PMID:17079861

Identification of nicotinamide N-methyltransferase as a novel serum tumor marker for colorectal cancer., PMID:16166432

Activation of nicotinamide N-methyltransferase gene promoter by hepatocyte nuclear factor-1beta in human papillary thyroid cancer cells., PMID:15486044

Expression of nicotinamide N-methyltransferase (E.C. 2.1.1.1) in the Parkinsonian brain., PMID:11853016

Nicotinamide-N-methyltransferase is higher in the lumbar cerebrospinal fluid of patients with Parkinson's disease., PMID:11154840

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-NNMT Polyclonal Antibody [PHE26401]
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