Anti-HNRNPA2B1 Polyclonal Antibody

Catalog No.

PHD53101

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human HNRNPA2B1 (Arg21-Gly103).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Heterogeneous nuclear ribonucleoproteins A2/B1, HNRPA2B1, hnRNP A2/B1, HNRNPA2B1

Purification

Purified by antigen affinity column.

Accession

P22626

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

UBE2I regulates the nuclear translocation of hnRNPA2B1 by contributing to SUMO modification in osteoarthritis., PMID:38955308

Galectin-3 does not interact with RNA directly., PMID:37815932

m6A methylation regulators as predictors for treatment of advanced urothelial carcinoma with anti-PDL1 agent., PMID:36189296

Preclinical Evaluation of hnRNPA2B1 Antibody in Human Triple-Negative Breast Cancer MDA-MB-231 Cells via PET Imaging., PMID:36015303

Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m6A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression., PMID:35279145

The Long Linker Region of Telomere-Binding Protein TRF2 Is Responsible for Interactions with Lamins., PMID:33804854

Monoclonal antibody against H1N1 influenza virus hemagglutinin cross reacts with hnRNPA1 and hnRNPA2/B1., PMID:32901845

Bacterial citrullinated epitopes generated by Porphyromonas gingivalis infection-a missing link for ACPA production., PMID:32532752

Neuronal BC RNA Transport Impairments Caused by Systemic Lupus Erythematosus Autoantibodies., PMID:31405929

Increased Expression of Exosomal AGAP2-AS1 (AGAP2 Antisense RNA 1) In Breast Cancer Cells Inhibits Trastuzumab-Induced Cell Cytotoxicity., PMID:30910994

Identification of RNA-binding proteins in exosomes capable of interacting with different types of RNA: RBP-facilitated transport of RNAs into exosomes., PMID:29689087

Cilostazol inhibits the expression of hnRNP A2/B1 and cytokines in human dermal microvascular endothelial cells., PMID:28850024

Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System., PMID:27773581

[Immunological markers of rheumatoid arthritis]., PMID:27117100

Antibodies to native and citrullinated RA33 (hnRNP A2/B1) challenge citrullination as the inciting principle underlying loss of tolerance in rheumatoid arthritis., PMID:26865600

Analysis of Characteristics Similar to Autoimmune Disease in Keloid Patients., PMID:26296635

Nanoparticle-conjugated aptamer targeting hnRNP A2/B1 can recognize multiple tumor cells and inhibit their proliferation., PMID:26107993

Inhibition of Inflammation and Bone Erosion by RNA Interference-Mediated Silencing of Heterogeneous Nuclear RNP A2/B1 in Two Experimental Models of Rheumatoid Arthritis., PMID:26017221

Heterogeneous Nuclear Ribonucleoprotein A2/B1 as a Target Antigen in Han Chinese for BD Patients., PMID:25925770

Anti-hnRNP B1 (RA33) autoantibodies are associated with the clinical phenotype in Russian patients with rheumatoid arthritis and systemic sclerosis., PMID:24883333

Abnormal distribution of heterogeneous nuclear ribonucleoproteins in sporadic inclusion body myositis., PMID:24857366

SPRi-based strategy to identify specific biomarkers in systemic lupus erythematosus, rheumatoid arthritis and autoimmune hepatitis., PMID:24376828

The HILDA complex coordinates a conditional switch in the 3'-untranslated region of the VEGFA mRNA., PMID:23976881

Translatome analysis of CHO cells to identify key growth genes., PMID:23876478

Both the sera of patients with Behçet's disease and Streptococcus sanguis stimulate membrane expression of hnRNP A2/B1 in endothelial cells., PMID:23445441

Serum IgA reactivity against GroEL of Streptococcus sanguinis and human heterogeneous nuclear ribonucleoprotein A2/B1 in patients with Behçet disease., PMID:23137016

Closing the serological gap: promising novel biomarkers for the early diagnosis of rheumatoid arthritis., PMID:22664776

The lectin Helix pomatia agglutinin recognizes O-GlcNAc containing glycoproteins in human breast cancer., PMID:22322011

Identification of HnRNP-A2/B1 as a target antigen of anti-endothelial cell IgA antibody in Behçet's disease., PMID:22205302

Up-regulation and subcellular localization of hnRNP A2/B1 in the development of hepatocellular carcinoma., PMID:20604928

Differential subcellular distributions and trafficking functions of hnRNP A2/B1 spliceoforms., PMID:20406423

Immunodominant T-cell epitopes of hnRNP-A2 associated with disease activity in patients with rheumatoid arthritis., PMID:20232340

Role of multi-hnRNP nuclear complex in regulation of tumor suppressor ANXA7 in prostate cancer cells., PMID:20190808

Identification of melanoma antigens using a Serological Proteome Approach (SERPA)., PMID:20181627

Mass spectrometric and peptide chip epitope mapping of rheumatoid arthritis autoantigen RA33., PMID:19940341

Immmunopathogenesis of rheumatoid arthritis; induction of arthritogenic autoimmune responses by proinflammatory stimuli., PMID:19758178

Comparison of osteopontin, beta-catenin and hnRNP B1 expression in lung carcinomas., PMID:19609729

Anti-hnRNP and other autoantibodies in systemic sclerosis with joint involvement., PMID:19483090

[Screening and Identification of Non-Small-Cell Lung Cancer Associated Antigen with SEREX.]., PMID:20719113

Proteomic analysis of methylarginine-containing proteins in HeLa cells by two-dimensional gel electrophoresis and immunoblotting with a methylarginine-specific antibody., PMID:19365714

B cell epitopes of the heterogeneous nuclear ribonucleoprotein A2: identification of a new specific antibody marker for active lupus disease., PMID:18495733

Significantly increased antibody response to heterogeneous nuclear ribonucleoproteins in cerebrospinal fluid of multiple sclerosis patients but not in patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis., PMID:18444084

Multiplexed dendritic targeting of alpha calcium calmodulin-dependent protein kinase II, neurogranin, and activity-regulated cytoskeleton-associated protein RNAs by the A2 pathway., PMID:18305102

Identification of hepatocellular-carcinoma-associated antigens and autoantibodies by serological proteome analysis combined with protein microarray., PMID:18161940

The rheumatoid arthritis-associated autoantigen hnRNP-A2 (RA33) is a major stimulator of autoimmunity in rats with pristane-induced arthritis., PMID:18025202

Cyclophilin A is required for CXCR4-mediated nuclear export of heterogeneous nuclear ribonucleoprotein A2, activation and nuclear translocation of ERK1/2, and chemotactic cell migration., PMID:17991743

Importance of spliceosomal RNP1 motif for intermolecular T-B cell spreading and tolerance restoration in lupus., PMID:17963484

[Experimental study for the targeting therapy of mouse lung carcinoma treated by anti-hnRNPB1 monoclonal antibody with 131I]., PMID:17953353

Prognostic and diagnostic relevance of hnRNP A2/B1, hnRNP B1 and S100 A2 in non-small cell lung cancer., PMID:17067748

[Expression and value of hnRNP B1 in sputum of patients with lung cancer by immunohistochemistry method]., PMID:21176464

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